Enhancing airway function and resolving mucus plugs: a case study on dupilumab treatment

Diego Bagnasco , Riccardo Picasso , Benedetta Bondi , Veronica Capuano , Elisa Testino , Carlo Martinoli , Fulvio Braido

Exploration of Asthma & Allergy ›› 2025, Vol. 3 ›› Issue (1) : 100980

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Exploration of Asthma & Allergy ›› 2025, Vol. 3 ›› Issue (1) :100980 DOI: 10.37349/eaa.2025.100980
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Enhancing airway function and resolving mucus plugs: a case study on dupilumab treatment
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Abstract

In the context of severe asthma, one of the causes of poor disease control has been identified in mucus plugs, which are real obstacles to the physiological flow of air in the bronchi. This clinical case will present the efficacy of dupilumab, as measured by respiratory function and chest computed tomography (CT) imaging, in reducing mucus plugs with consequent improvement in symptoms and function.

Keywords

Mucus plug / severe asthma / dupilumab / anti IL-4R / remodeling / epithelium

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Diego Bagnasco, Riccardo Picasso, Benedetta Bondi, Veronica Capuano, Elisa Testino, Carlo Martinoli, Fulvio Braido. Enhancing airway function and resolving mucus plugs: a case study on dupilumab treatment. Exploration of Asthma & Allergy, 2025, 3 (1) : 100980 DOI:10.37349/eaa.2025.100980

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