Left Bundle Branch Area Pacing: A Promising Strategy to Mitigate Pacing-Induced Cardiomyopathy

Tri Manh Ngo , Thang Viet Luong , Hai Nguyen Ngoc Dang , Tuan Van Le , Lam Viet Ngo , Phong Nguyen Vu , Tien Anh Hoang

Cardiovascular Innovations and Applications ›› 2026, Vol. 11 ›› Issue (1) : 972

PDF (922KB)
Cardiovascular Innovations and Applications ›› 2026, Vol. 11 ›› Issue (1) :972 DOI: 10.15212/CVIA.2026.0013
Original article
research-article
Left Bundle Branch Area Pacing: A Promising Strategy to Mitigate Pacing-Induced Cardiomyopathy
Author information +
History +
PDF (922KB)

Cite this article

Download citation ▾
Tri Manh Ngo, Thang Viet Luong, Hai Nguyen Ngoc Dang, Tuan Van Le, Lam Viet Ngo, Phong Nguyen Vu, Tien Anh Hoang. Left Bundle Branch Area Pacing: A Promising Strategy to Mitigate Pacing-Induced Cardiomyopathy. Cardiovascular Innovations and Applications, 2026, 11 (1) : 972 DOI:10.15212/CVIA.2026.0013

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, et al.. 2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2019. Vol. 74(7):e51-156

[2]

Khurshid S, Epstein AE, Verdino RJ, Lin D, Goldberg LR, Marchlinski FE, et al.. Incidence and predictors of right ventricular pacing-induced cardiomyopathy. Heart Rhythm. 2014. Vol. 11(9):1619-25

[3]

Khurshid S, Frankel DS. Pacing-induced cardiomyopathy. Cardiol Clin. 2023. Vol. 41(3):449-61

[4]

Huang W, Su L, Wu S, Xu L, Xiao F, Zhou X, et al.. A novel pacing strategy with low and stable output: pacing the left bundle branch immediately beyond the conduction block. Can J Cardiol. 2017. Vol. 33(12):1736.e1-3

[5]

Khurshid S, Obeng-Gyimah E, Supple GE, Schaller R, Lin D, Owens AT, et al.. Reversal of pacing-induced cardiomyopathy following cardiac resynchronization therapy. JACC Clin Electrophysiol. 2018. Vol. 4(2):168-77

[6]

Chung MK, Patton KK, Lau CP, Dal Forno ARJ, Al-Khatib SM, Arora V, et al.. 2023 HRS/APHRS/LAHRS guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure. Heart Rhythm. 2023. Vol. 20(9):e17-91

[7]

Burri H, Jastrzebski M, Cano Ó, Čurila K, de Pooter J, Huang W, et al.. EHRA clinical consensus statement on conduction system pacing implantation: endorsed by the Asia Pacific Heart Rhythm Society (APHRS), Canadian Heart Rhythm Society (CHRS), and Latin American Heart Rhythm Society (LAHRS). Europace. 2023. Vol. 25(4):1208-36

[8]

Tan ESJ, Soh R, Boey E, Lee JY, de Leon J, Chan SP, et al.. Comparison of pacing performance and clinical outcomes between left bundle branch and his bundle pacing. JACC Clin Electrophysiol. 2023. Vol. 9(8 Pt1):1393-403

[9]

Huang W, Chen X, Su L, Wu S, Xia X, Vijayaraman P. A beginner’s guide to permanent left bundle branch pacing. Heart Rhythm. 2019. Vol. 16(12):1791-6

[10]

Wu S, Chen X, Wang S, Xu L, Xiao F, Huang Z, et al.. Evaluation of the criteria to distinguish left bundle branch pacing from left ventricular septal pacing. JACC Clin Electrophysiol. 2021. Vol. 7(9):1166-77

[11]

Lakshman H, Chowdhury M, Ahmed A, Woods E, Flemengos G, Abdou C, et al.. Clinical and electrophysiological outcomes of left bundle area pacing compared to biventricular pacing: an updated meta-analysis. J Innov Card Rhythm Manag. 2024. Vol. 15(5):5858-65

[12]

Ahsan I, Hennawi HA, Bedi A, Khan MK, Duseja N, Ho RT. Left bundle branch area pacing versus right ventricular pacing in patients with atrioventricular block: a systematic review and meta-analysis. J Cardiovasc Electrophysiol. 2025. Vol. 36(2):501-11

[13]

Shroff JP, Raja DC, Abhilash SP, Mehta A, Abhayaratna WP, Vijayaraman P, et al.. Left bundle branch area pacing vs right ventricular pacing in preserved or mildly reduced ejection fraction: the PACE-HF trial. Eur Heart J. 2025. ehaf724

[14]

Jastrzębski M, Kiełbasa G, Cano O, Curila K, Zanon F, Pestrea C, et al.. Left bundle branch area pacing vs right ventricular pacing for atrioventricular block: the MELOS RELOADED study. Eur Heart J. 2026. Vol. 47(13):1541-50

[15]

Wang Y, Zhu H, Hou X, Wang Z, Zou F, Qian Z, et al.. Randomized trial of left bundle branch vs biventricular pacing for cardiac resynchronization therapy. J Am Coll Cardiol. 2022. Vol. 80(13):1205-16

[16]

Vijayaraman P, Sharma PS, Cano Ó, Ponnusamy SS, Herweg B, Zanon F, et al.. Comparison of left bundle branch area pacing and biventricular pacing in candidates for resynchronization therapy. J Am Coll Cardiol. 2023. Vol. 82(3):228-41

[17]

Yousaf A, Ahmad S, Peltz J, Ahsan MJ, Abbas KS, Muhammad S, et al.. Left bundle branch area pacing vs biventricular pacing for cardiac resynchronization: a systematic review and meta-analysis. Heart Rhythm O2. 2023. Vol. 4(11):671-80

[18]

Chen X, Liu X, Li R, Wang Z, Liang Y, Zhang L, et al.. Long-term outcomes of left bundle-branch pacing vs biventricular pacing in heart failure: the HeartSync-LBBP Randomized Clinical Trial. JAMA Cardiol. 2026. Vol. 11(4):352-9

[19]

Zimerman A, dal Forno A, Rohde LE, Ternes CM, Alves FD, Damiani LP, et al.. Conduction system vs biventricular pacing in heart failure: the PhysioSync-HF Randomized Clinical Trial. JAMA Cardiol. 2026. Vol. 11(4):360-8

[20]

Glikson M, Burri H, Abdin A, Cano O, Curila K, De Pooter J, et al.. European Society of Cardiology (ESC) clinical consensus statement on indications for conduction system pacing, with special contribution of the European Heart Rhythm Association of the ESC and endorsed by the Asia Pacific Heart Rhythm Society, the Canadian Heart Rhythm Society, the Heart Rhythm Society, and the Latin American Heart Rhythm Society. Europace. 2025. Vol. 27(4):euaf050

PDF (922KB)

0

Accesses

0

Citation

Detail

Sections
Recommended

/