Mesenchymal stem cells with an enhanced antioxidant capacity integrate as smoothmuscle cells in amodel of diabetic detrusor underactivity

Chae-Min Ryu; Yong Hwan Kim; Jung-Hyun Shin; Seungun Lee; Hyein Ju; Yun Ji Nam; Hyungu Kwon; Min-Young Jo; Jinah Lee; Hyun Jun Im; Min Gi Jang; Ki-Sung Hong; Hyung-Min Chung; Sang Hoon Song; Myung-Soo Choo; Seong Who Kim; Juhyun Park; Dong-Myung Shin

doi:10.1002/ctm2.70052

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (10) :e70052 DOI: 10.1002/ctm2.70052

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Mesenchymal stem cells with an enhanced antioxidant capacity integrate as smoothmuscle cells in amodel of diabetic detrusor underactivity

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¹. Center for Cell Therapy, Asan Medical Center, Seoul, South Korea

². Department of Cell and Genetic Engineering, Asan Medical Center, Brain Korea 21 Project, University of Ulsan College of Medicine, Seoul, South Korea

³. Department of Urology, Mokdong Hospital, Ewha Womans University, Seoul, South Korea

⁴. Department of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, South Korea

⁵. Mirae Cell Bio Co., Ltd., Seoul, South Korea

⁶. Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

⁷. Dr Joo Urology Clinic, Seoul, South Korea

⁸. Department of Biochemistry and Molecular Biology, Asan Medical Center, Brain Korea 21 Project, University of Ulsan College of Medicine, Seoul, South Korea

swhokim@amc.seoul.kr

urojpark@amc.seoul.kr

d0shin03@amc.seoul.kr

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Chae-Min Ryu, Yong Hwan Kim, Jung-Hyun Shin, Seungun Lee, Hyein Ju, Yun Ji Nam, Hyungu Kwon, Min-Young Jo, Jinah Lee, Hyun Jun Im, Min Gi Jang, Ki-Sung Hong, Hyung-Min Chung, Sang Hoon Song, Myung-Soo Choo, Seong Who Kim, Juhyun Park, Dong-Myung Shin. Mesenchymal stem cells with an enhanced antioxidant capacity integrate as smoothmuscle cells in amodel of diabetic detrusor underactivity. Clinical and Translational Medicine, 2024, 14(10): e70052 DOI:10.1002/ctm2.70052

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References

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[8]	Lim J, Heo J, Ju H, et al. Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway. Sci Adv. 2020; 6: eaba1334.

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2024 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.