CD81 promotes proliferation and predicts survival in lung squamous cell carcinoma

Ryu Kanzaki , Steven Reid , Paulina Bolivar , Sara Larsson , Yasushi Shintani , Kristian Pietras

Clinical and Translational Medicine ›› 2026, Vol. 16 ›› Issue (4) : e70672

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Clinical and Translational Medicine ›› 2026, Vol. 16 ›› Issue (4) :e70672 DOI: 10.1002/ctm2.70672
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CD81 promotes proliferation and predicts survival in lung squamous cell carcinoma
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CD81 / lung squamous cell carcinoma

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Ryu Kanzaki, Steven Reid, Paulina Bolivar, Sara Larsson, Yasushi Shintani, Kristian Pietras. CD81 promotes proliferation and predicts survival in lung squamous cell carcinoma. Clinical and Translational Medicine, 2026, 16 (4) : e70672 DOI:10.1002/ctm2.70672

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Ye X, Deng J, Dong C, Pan X, Lu Y. Characterization and verification of CD81 as a potential target in lung squamous cell carcinoma. Biochem Biophys Res Commun. 2024; 692:149344.

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Kanzaki R, Reid S, Bolivar P, et al. FHL2 expression by cancer-associated fibroblasts promotes metastasis and angiogenesis in lung adenocarcinoma. Int J Cancer. 2024; 156(2): 431-446.

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Ramos EK, Tsai CF, Jia Y, et al. Machine learning-assisted elucidation of CD81‒CD44 interactions in promoting cancer stemness and extracellular vesicle integrity. eLife. 2022; 11:e82669.

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Suwatthanarak T, Usuba K, Kuroha K, Tanaka M, Okochi M. Screening of EWI-2-derived peptides for targeting tetraspanin CD81 and their effect on cancer cell migration. Biomolecules. 2023; 13(3): 510.

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2026 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

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