Single-cell and spatial transcriptomics uncover neoadjuvant chemotherapy-resistant malignant cells with inhibitory signalling on B cells in gastric cancer

Pei-Yi Han , Xiang-Xi Ye , Xiao Yang , Lin Li , Xuan Zhao , Yan-Fei Shao , Jing Sun , Lu Zang , Ze-Guang Han , Min-Hua Zheng

Clinical and Translational Medicine ›› 2026, Vol. 16 ›› Issue (2) : e70600

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Clinical and Translational Medicine ›› 2026, Vol. 16 ›› Issue (2) :e70600 DOI: 10.1002/ctm2.70600
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Single-cell and spatial transcriptomics uncover neoadjuvant chemotherapy-resistant malignant cells with inhibitory signalling on B cells in gastric cancer
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Pei-Yi Han, Xiang-Xi Ye, Xiao Yang, Lin Li, Xuan Zhao, Yan-Fei Shao, Jing Sun, Lu Zang, Ze-Guang Han, Min-Hua Zheng. Single-cell and spatial transcriptomics uncover neoadjuvant chemotherapy-resistant malignant cells with inhibitory signalling on B cells in gastric cancer. Clinical and Translational Medicine, 2026, 16(2): e70600 DOI:10.1002/ctm2.70600

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2026 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

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