Liquid biopsy biomarkers for early detection of gastrointestinal cancers: Current landscape and emerging technologies

Muhammad Anees , Christopher Sherry , Hyun Y. Park , Erin E. Grayhack , Arul Goel , Alisha F. Khan , Ashten Omstead , David L. Bartlett , Ajay Goel , Neda Dadgar , Patrick L. Wagner , Ali H. Zaidi

Clinical and Translational Medicine ›› 2026, Vol. 16 ›› Issue (3) : e70594

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Clinical and Translational Medicine ›› 2026, Vol. 16 ›› Issue (3) :e70594 DOI: 10.1002/ctm2.70594
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Liquid biopsy biomarkers for early detection of gastrointestinal cancers: Current landscape and emerging technologies
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Abstract

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Keywords

cell-free DNA methylation / circulating tumour cells (CTCs) / circulating tumour DNA (ctDNA) / early cancer detection / extracellular vesicles/exosomes / fragmentomics / gastrointestinal cancers / liquid biopsy / multi-cancer early detection (MCED) / tumour-educated platelets (TEPs)

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Muhammad Anees, Christopher Sherry, Hyun Y. Park, Erin E. Grayhack, Arul Goel, Alisha F. Khan, Ashten Omstead, David L. Bartlett, Ajay Goel, Neda Dadgar, Patrick L. Wagner, Ali H. Zaidi. Liquid biopsy biomarkers for early detection of gastrointestinal cancers: Current landscape and emerging technologies. Clinical and Translational Medicine, 2026, 16 (3) : e70594 DOI:10.1002/ctm2.70594

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