Gene expression differences in differentially methylated sites associated with HIV status and cocaine use

Eric J. Earley; Bryan C. Quach; Fang Fang; Laura J. Bierut; M-J S. Milloy; Kanna Hayashi; Kora DeBeck; Dana B. Hancock; Bradley E. Aouizerat; Ke Xu; Eric Otto Johnson

doi:10.1002/ctm2.70466

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (9) : e70466 DOI: 10.1002/ctm2.70466

LETTER TO THE JOURNAL

Gene expression differences in differentially methylated sites associated with HIV status and cocaine use

Author information +

¹. GenOmics and Translational Research Center, RTI International, Durham, North Carolina, USA

². Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA

³. British Columbia Centre on Substance Use, Vancouver, British Columbia, Canada

⁴. Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

⁵. Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada

⁶. School of Public Policy, Simon Fraser University, Vancouver, British Columbia, Canada

⁷. Bluestone Center for Clinical Research, College of Dentistry, New York University, New York, New York, USA

⁸. Department of Oral and Maxillofacial Surgery, College of Dentistry, New York University, New York, New York, USA

⁹. Department of Psychiatry, School of Medicine, Yale University, New Haven, Connecticut, USA

¹⁰. VA Connecticut, Healthcare System, West Haven, Connecticut, USA

¹¹. RTI Fellow Program, RTI International, Durham, North Carolina, USA

ejohnson@rti.org

Show less

History +

PDF

Cite this article

Download citation ▾

Eric J. Earley, Bryan C. Quach, Fang Fang, Laura J. Bierut, M-J S. Milloy, Kanna Hayashi, Kora DeBeck, Dana B. Hancock, Bradley E. Aouizerat, Ke Xu, Eric Otto Johnson. Gene expression differences in differentially methylated sites associated with HIV status and cocaine use. Clinical and Translational Medicine, 2025, 15(9): e70466 DOI:10.1002/ctm2.70466

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Titanji BK, Gwinn M, Marconi VC, Sun YV. Epigenome-wide epidemiologic studies of human immunodeficiency virus infection, treatment, and disease progression. Clin Epigenetics. 2022; 14(1): 8.

[2]	Le Clerc S, Limou S, Zagury JF, Large-Scale “OMICS” Studies to explore the physiopatholgy of HIV-1 infection. Front Genet. 2019; 10: 799.

[3]	Hunt PW. HIV and inflammation: mechanisms and consequences. Curr HIV/AIDS Rep. 2012; 9(2): 139-147.

[4]	Shu C, Justice AC, Zhang X, et al. DNA methylation mediates the effect of cocaine use on HIV severity. Clin Epigenetics. 2020; 12(1): 140.

[5]	Gaddis N, Mathur R, Marks J, et al. Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. Sci Rep. 2022; 12(1): 16873.

[6]	Shu C, Jaffe AE, Sabunciyan S, et al. Epigenome-wide association scan identifies methylation sites associated with HIV infection. Epigenomics. 2020; 12(21): 1917-1927.

[7]	Liberzon A, Birger C, Thorvaldsdottir H, Ghandi M, Mesirov JP, Tamayo P. The Molecular Signatures Database (MSigDB) hallmark gene set collection. Cell Syst. 2015; 1(6): 417-425.

[8]	Meissner TB, Li A, Kobayashi KS. NLRC5: a newly discovered MHC class I transactivator (CITA). Microbes Infect. 2012; 14(6): 477-484.

[9]	Cui J, Zhu L, Xia X, et al. NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways. Cell. 2010; 141(3): 483-496.

[10]	Puré E, Cuff CA. A crucial role for CD44 in inflammation. Trends Mol Med. 2001; 7(5): 213-221.

RIGHTS & PERMISSIONS

2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.