Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma

Longyan Wang; Peng Tan; Fei Wang; Huiming Huang; Xuejiao Wei; Zhuguo Wang; Xinyu Qiu; Yufeng Gao; Ruoxin Zhang; Pengfei Tu; Jun Li; Zhongdong Hu

doi:10.1002/ctm2.70460

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (8) : e70460 DOI: 10.1002/ctm2.70460

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Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma

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Longyan Wang, Peng Tan, Fei Wang, Huiming Huang, Xuejiao Wei, Zhuguo Wang, Xinyu Qiu, Yufeng Gao, Ruoxin Zhang, Pengfei Tu, Jun Li, Zhongdong Hu. Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma. Clinical and Translational Medicine, 2025, 15(8): e70460 DOI:10.1002/ctm2.70460

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2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.