Glutamate as a therapeutic strategy to promote liver regeneration

María del Mar Rigual; Nabil Djouder

doi:10.1002/ctm2.70421

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (7) : e70421 DOI: 10.1002/ctm2.70421

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Glutamate as a therapeutic strategy to promote liver regeneration

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María del Mar Rigual, Nabil Djouder. Glutamate as a therapeutic strategy to promote liver regeneration. Clinical and Translational Medicine, 2025, 15(7): e70421 DOI:10.1002/ctm2.70421

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References

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[2]	Rigual MDM, Sanchez Sanchez P, Djouder N. Is liver regeneration key in hepatocellular carcinoma development? Trends Cancer. 2022; 9(2): 140-157.

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[5]	Rigual MDM, Angulo-Aguado M, Zagorac S, et al. Macrophages harness hepatocyte glutamate to boost liver regeneration. Nature. 2025; 641: 1005-1016.

[6]	Chaves-Pérez A, Thompson S, Djouder N. Roles and functions of the unconventional prefoldin URI. Adv Exp Med Biol. 2018; 1106: 95-108.

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[8]	Garrido A, Kim E, Teijeiro A, et al. Histone acetylation of bile acid transporter genes plays a critical role in cirrhosis. J Hepatol. 2022; 76(4): 850-861.

[9]	Chaves-Perez A, Santos-de-Frutos K, de la Rosa S, Herranz-Montoya I, Perna C, Djouder N. Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation. J Exp Med. 2022; 219(11): e20212405.

[10]	Chaves-Perez A, Yilmaz M, Perna C, de la Rosa S, Djouder N. URI is required to maintain intestinal architecture during ionizing radiation. Science. 2019; 364(6443): eaaq1165.

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2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.