DNA methylation profiles reveals STAB1-mediated endothelial cell and immune cell interactions in Moyamoya disease

Shihao He , Zhenyu Zhou , Rui Liang , Chengxu Lei , Yutong Liu , Jialong Yuan , Youjia Tang , Yuanli Zhao

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (6) : e70367

PDF
Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (6) : e70367 DOI: 10.1002/ctm2.70367
LETTER TO THE JOURNAL

DNA methylation profiles reveals STAB1-mediated endothelial cell and immune cell interactions in Moyamoya disease

Author information +
History +
PDF

Cite this article

Download citation ▾
Shihao He, Zhenyu Zhou, Rui Liang, Chengxu Lei, Yutong Liu, Jialong Yuan, Youjia Tang, Yuanli Zhao. DNA methylation profiles reveals STAB1-mediated endothelial cell and immune cell interactions in Moyamoya disease. Clinical and Translational Medicine, 2025, 15(6): e70367 DOI:10.1002/ctm2.70367

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Gonzalez NR, Amin-Hanjani S, Bang OY, et al. Adult Moyamoya disease and syndrome: current perspectives and future directions: a scientific statement from the American Heart Association/American Stroke Association. Stroke. 2023; 54: e465-e479.

[2]

Sung HY, Lee JY, Park AK, et al. Aberrant promoter hypomethylation of sortilin 1: a Moyamoya disease biomarker. J Stroke. 2018; 20: 350-361.

[3]

Tokairin K, Ito M, Lee AG, et al. Genome-wide DNA methylation profiling reveals low methylation variability in Moyamoya disease. Transl Stroke Res. 2024.

[4]

Matsuo M, Nadanaka S, Soga M, et al. Vulnerability to shear stress caused by altered peri-endothelial matrix is a key feature of Moyamoya disease. Sci Rep. 2021; 11.

[5]

Ye F, Niu X, Liang F, et al. RNF213 loss-of-function promotes pathological angiogenesis in Moyamoya disease via the Hippo pathway. Brain. 2023; 146: 4674-4689.

[6]

Adachi H, Tsujimoto M. FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities. J Biol Chem. 2002; 277: 34264-34270.

[7]

Salmi M, Koskinen K, Henttinen T, Elima K, Jalkanen S. CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium. Blood. 2004; 104: 3849-3857.

[8]

Lužnik Z, Anchouche S, Dana R, Yin J. Regulatory T cells in angiogenesis. J Immunol. 2020; 205: 2557-2565.

[9]

Weng L, Cao X, Han L, et al. Association of increased Treg and Th17 with pathogenesis of Moyamoya disease. Sci Rep. 2017; 7.

[10]

Li Z, Li M, Shi SX, et al. Brain transforms natural killer cells that exacerbate brain edema after intracerebral hemorrhage. J Exp Med. 2020; 217.

RIGHTS & PERMISSIONS

2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

AI Summary AI Mindmap
PDF

8

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/