Early molecular changes predict cancer cachexia in LKB1-deleted mouse models of NSCLC

Gloriana Ndembe; Andrea David Re Cecconi; Federica Palo; Dorina Belotti; Laura Sala; Selena Foroni; Eugenio Scanziani; Rosanna Piccirillo; Massimo Broggini; Mirko Marabese

doi:10.1002/ctm2.70360

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (7) : e70360 DOI: 10.1002/ctm2.70360

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Early molecular changes predict cancer cachexia in LKB1-deleted mouse models of NSCLC

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Gloriana Ndembe, Andrea David Re Cecconi, Federica Palo, Dorina Belotti, Laura Sala, Selena Foroni, Eugenio Scanziani, Rosanna Piccirillo, Massimo Broggini, Mirko Marabese. Early molecular changes predict cancer cachexia in LKB1-deleted mouse models of NSCLC. Clinical and Translational Medicine, 2025, 15(7): e70360 DOI:10.1002/ctm2.70360

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References

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[6]	Pretto F, Ghilardi C, Moschetta M, et al. Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle. Oncotarget. 2015; 6(5): 3043-3054.

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2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.