Imbalanced NK cell subpopulations and TIGIT expression limit cetuximab efficacy in colorectal cancer: A promising target for treatment enhancement

Carmen Navarrete-Sirvent , Ana Mantrana , Aurora Rivas-Crespo , Alejandra Díaz-Chacón , Nerea M. Herrera-Casanova , María Teresa Sánchez-Montero , Marta Toledano-Fonseca , María Victoria García-Ortiz , María José Ortiz-Morales , Gema Pulido , Mª Teresa Cano , Auxiliadora Gómez-España , Rafael González-Fernández , Lionel Le Bourhis , Silvia Guil-Luna , Antonio Rodríguez-Ariza , Enrique Aranda

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (6) : e70351

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Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (6) : e70351 DOI: 10.1002/ctm2.70351
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Imbalanced NK cell subpopulations and TIGIT expression limit cetuximab efficacy in colorectal cancer: A promising target for treatment enhancement

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Carmen Navarrete-Sirvent, Ana Mantrana, Aurora Rivas-Crespo, Alejandra Díaz-Chacón, Nerea M. Herrera-Casanova, María Teresa Sánchez-Montero, Marta Toledano-Fonseca, María Victoria García-Ortiz, María José Ortiz-Morales, Gema Pulido, Mª Teresa Cano, Auxiliadora Gómez-España, Rafael González-Fernández, Lionel Le Bourhis, Silvia Guil-Luna, Antonio Rodríguez-Ariza, Enrique Aranda. Imbalanced NK cell subpopulations and TIGIT expression limit cetuximab efficacy in colorectal cancer: A promising target for treatment enhancement. Clinical and Translational Medicine, 2025, 15(6): e70351 DOI:10.1002/ctm2.70351

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2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

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