Macrophage C1q contributes to pulmonary fibrosis by disturbing the metabolism of alveolar epithelial cells

Fenja Prüfer; Beatrix Steer; Eva Kaufmann; Peter Wolf; Barbara Adler; Martina Korfei; Andreas Günther; Melanie Königshoff; Heiko Adler

doi:10.1002/ctm2.70341

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (5) : e70341 DOI: 10.1002/ctm2.70341

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Macrophage C1q contributes to pulmonary fibrosis by disturbing the metabolism of alveolar epithelial cells

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¹. Comprehensive Pneumology Center, Research Unit Lung Repair and Regeneration, Helmholtz Zentrum München - German Research Center for Environmental Health, Munich, Germany

². University Hospital Grosshadern, Ludwig-Maximilians-University Munich, Munich, Germany

³. German Center for Lung Research (DZL/CPC-M), Munich, Germany

⁴. Institute of Asthma and Allergy Prevention, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

⁵. INCYTON GmbH, Planegg, Germany

⁶. Max von Pettenkofer Institute & Gene Center, Virology, Faculty of Medicine, Ludwig- Maximilians-University Munich, Munich, Germany

⁷. Department of Internal Medicine, Justus-Liebig-University Giessen, Giessen, Germany

⁸. German Center for Lung Research (DZL), Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany

⁹. Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

¹⁰. Walther Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-University Munich, Munich, Germany

heiko.adler@lrz.uni-muenchen.de

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Fenja Prüfer, Beatrix Steer, Eva Kaufmann, Peter Wolf, Barbara Adler, Martina Korfei, Andreas Günther, Melanie Königshoff, Heiko Adler. Macrophage C1q contributes to pulmonary fibrosis by disturbing the metabolism of alveolar epithelial cells. Clinical and Translational Medicine, 2025, 15(5): e70341 DOI:10.1002/ctm2.70341

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References

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2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.