Abnormal lineage differentiation of peri-implantation aneuploid embryos revealed by single-cell RNA sequencing

Xueyao Chen; Hanwen Yu; Yu Yin; Bing Cai; Gaohui shi; Yan Xu; Lujuan Rong; Xiu Yu; Boyan Wang; Canquan Zhou; Jichang Wang; Chenhui Ding; Tianqing Li; Yanwen Xu

doi:10.1002/ctm2.70326

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (5) : e70326 DOI: 10.1002/ctm2.70326

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Abnormal lineage differentiation of peri-implantation aneuploid embryos revealed by single-cell RNA sequencing

Xueyao Chen ¹^,²^,³
, Hanwen Yu ⁴^,⁵^,⁶
, Yu Yin ⁷
, Bing Cai ¹^,²^,³
, Gaohui shi ⁷
, Yan Xu ¹^,²^,³
, Lujuan Rong ⁶
, Xiu Yu ⁴^,⁵^,⁶
, Boyan Wang ¹^,²^,³
, Canquan Zhou ¹^,²^,³
, Jichang Wang ¹^,⁴^,⁵^,⁶
, Chenhui Ding ¹^,²^,³
, Tianqing Li ⁷
, Yanwen Xu ¹^,²^,³

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Xueyao Chen, Hanwen Yu, Yu Yin, Bing Cai, Gaohui shi, Yan Xu, Lujuan Rong, Xiu Yu, Boyan Wang, Canquan Zhou, Jichang Wang, Chenhui Ding, Tianqing Li, Yanwen Xu. Abnormal lineage differentiation of peri-implantation aneuploid embryos revealed by single-cell RNA sequencing. Clinical and Translational Medicine, 2025, 15(5): e70326 DOI:10.1002/ctm2.70326

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2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.