Interleukin 27 deficiency drives dilated cardiomyopathy by ferroptosis

References

[1] Harding D, Chong MHA, Lahoti N, Bigogno CM, Prema R, Mohiddin SA, et al. Dilated cardiomyopathy and chronic cardiac inflammation: pathogenesis, diagnosis and therapy. J Intern Med. 2023; 293(1): 23-47.

[2] Ye J, Wang Y, Wang Z, Liu L, Yang Z, Wang M, et al. Roles and mechanisms of interleukin-12 family members in cardiovascular diseases: opportunities and challenges. Front Pharmacol. 2020; 11: 129.

[3] Noutsias M, Rohde M, Göldner K, Block A, Blunert K, Hemaidan L, et al. Expression of functional T-cell markers and T-cell receptor Vbeta repertoire in endomyocardial biopsies from patients presenting with acute myocarditis and dilated cardiomyopathy. Eur J Heart Fail. 2011; 13(6): 611-618.

[4] Chen Y, Zhang R, Zeng L, Wei H, Chen Y, Zeng J. IL-27 genetic variation and susceptibility of dilated cardiomyopathy in Chinese Han population. Per Med. 2017; 14(5): 401-408.

[5] Zeng C, Duan F, Hu J, Luo B, Huang B, Lou X, et al. NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy. Redox Biol. 2020; 34: 101523.

[6] Haesen S, Jager MM, Brillouet A, de Laat I, Vastmans L, Verghote E, et al. Pyridoxamine limits cardiac dysfunction in a rat model of doxorubicin-induced cardiotoxicity. Antioxidants. 2024; 13(1): 112.

[7] Gao W, Wang X, Zhou Y, Wang X, Yu Y. Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy. Signal Transduct Target Ther. 2022; 7(1): 196.

[8] Mancias JD, Wang X, Gygi SP, Harper JW, Kimmelman AC. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature. 2014; 509(7498): 105-109.

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