Proteogenomic characterisation of primary oral cancer unveils extracellular matrix remodelling and immunosuppressive microenvironment linked to lymph node metastasis

Yu Liu; Zhenyu Yang; Jingya Jane Pu; Jie Zhong; Ui-Soon Khoo; Yu-Xiong Su; Gao Zhang

doi:10.1002/ctm2.70261

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (3) : e70261 DOI: 10.1002/ctm2.70261

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Proteogenomic characterisation of primary oral cancer unveils extracellular matrix remodelling and immunosuppressive microenvironment linked to lymph node metastasis

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lymph node metastasis / oral squamous cell carcinoma / single-cell analysis

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Yu Liu, Zhenyu Yang, Jingya Jane Pu, Jie Zhong, Ui-Soon Khoo, Yu-Xiong Su, Gao Zhang. Proteogenomic characterisation of primary oral cancer unveils extracellular matrix remodelling and immunosuppressive microenvironment linked to lymph node metastasis. Clinical and Translational Medicine, 2025, 15(3): e70261 DOI:10.1002/ctm2.70261

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2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.