Ferroptosis of T cell in inflammation and tumour immunity
Xueli Xia , Haisheng Wu , Yuxuan Chen , Huiyong Peng , Shengjun Wang
Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (3) : e70253
Ferroptosis of T cell in inflammation and tumour immunity
•Ferroptosis-related mechanisms significantly affect the biology of CD4+ T-cell subsets and are further involved in inflammatory diseases. | |
•Crosstalk between CD8+ T cells and tumour cells induces ferroptosis in the tumour microenvironment. | |
•Glutathione peroxidase 4 loss promotes regulatory T-cell ferroptosis to enhance anti-tumour immunity. |
CD4 + T cell / CD8 + T cell / ferroptosis / inflammation / tumour
2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.
/
| 〈 |
|
〉 |