EpCAM deficiency causes the premature ageing of intestinal stem cells via EGFR/SP1/mTORC1 pathway

Keying Li; Changlong Xu; Lulu Liu; Yunjuan Wang; Jun Chen; Chunyuan Li; Zitong Peng; Xiaoqian Li; Gang Chang; Zili Lei; Yanhong Yang

doi:10.1002/ctm2.70219

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (2) : e70219 DOI: 10.1002/ctm2.70219

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EpCAM deficiency causes the premature ageing of intestinal stem cells via EGFR/SP1/mTORC1 pathway

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Keying Li, Changlong Xu, Lulu Liu, Yunjuan Wang, Jun Chen, Chunyuan Li, Zitong Peng, Xiaoqian Li, Gang Chang, Zili Lei, Yanhong Yang. EpCAM deficiency causes the premature ageing of intestinal stem cells via EGFR/SP1/mTORC1 pathway. Clinical and Translational Medicine, 2025, 15(2): e70219 DOI:10.1002/ctm2.70219

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2025 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.