Mesoscopic connectome enters the new age of single-neuron projectome

Ning Li , Hua He , Chun Xu

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (1) : e70155

PDF
Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (1) : e70155 DOI: 10.1002/ctm2.70155
COMMENTARY

Mesoscopic connectome enters the new age of single-neuron projectome

Author information +
History +
PDF

Keywords

hippocampus / Mesoscopic connectome / single-neuron projectome

Cite this article

Download citation ▾
Ning Li, Hua He, Chun Xu. Mesoscopic connectome enters the new age of single-neuron projectome. Clinical and Translational Medicine, 2025, 15(1): e70155 DOI:10.1002/ctm2.70155

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Scoville WB, Milner B. Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychiatry. 1957;20:11-21.

[2]

O’Keefe J, Nadel L. The Hippocampus as a Cognitive Map. Oxford University Press; 1978.

[3]

Henke PG. Hippocampal pathway to the amygdala and stress ulcer development. Brain Res Bull. 1990;25:691-695.

[4]

Tottenham N, Sheridan MA. A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing. Front Hum Neurosci. 2009;3:68.

[5]

Andersen P, Bliss TV, Skrede KK. Lamellar organization of hippocampal pathways. Exp Brain Res. 1971;13:222-238.

[6]

Aggleton JP, Christiansen K. The subiculum: the heart of the extended hippocampal system. Prog Brain Res. 2015;219:65-82.

[7]

Fanselow MS, Dong HW. Are the dorsal and ventral hippocampus functionally distinct structures? Neuron. 2010;65:7-19.

[8]

Strange BA, Witter MP, Lein ES, Moser EI. Functional organization of the hippocampal longitudinal axis. Nat Rev Neurosci. 2014;15:655-669.

[9]

Swanson LW, Cowan WM. An autoradiographic study of the organization of the efferent connections of the hippocampal formation in the rat. J Comp Neurol. 1977;172:49-84.

[10]

Pitkanen A, Pikkarainen M, Nurminen N, Ylinen A. Reciprocal connections between the amygdala and the hippocampal formation, perirhinal cortex, and postrhinal cortex in rat. A review. Ann NY Acad Sci. 2000;911:369-391.

[11]

Zhou Y, Zhu H, Liu Z, et al. A ventral CA1 to nucleus accumbens core engram circuit mediates conditioned place preference for cocaine. Nat Neurosci. 2019;22:1986-1999.

[12]

Okuyama T, Kitamura T, Roy DS, Itohara S, Tonegawa S. Ventral CA1 neurons store social memory. Science. 2016;353:1536-1541.

[13]

Xu C, Krabbe S, Grundemann J, et al. Distinct hippocampal pathways mediate dissociable roles of context in memory retrieval. Cell. 2016;167:961-972. e916.

[14]

Sweeney P, Yang Y. An excitatory ventral hippocampus to lateral septum circuit that suppresses feeding. Nat Commun. 2015;6:10188.

[15]

Ciocchi S, Passecker J, Malagon-Vina H, Mikus N, Klausberger T. Brain computation. Selective information routing by ventral hippocampal CA1 projection neurons. Science. 2015;348:560-563.

[16]

Phillips ML, Robinson HA, Pozzo-Miller L. Ventral hippocampal projections to the medial prefrontal cortex regulate social memory. eLife. 2019;8:e44182.

[17]

Ito HT, Zhang SJ, Witter MP, Moser EI, Moser MB. A prefrontal-thalamo-hippocampal circuit for goal-directed spatial navigation. Nature 2015;522:50-55.

[18]

Jimenez JC, Su K, Goldberg AR, et al. Anxiety cells in a hippocampal-hypothalamic circuit. Neuron. 2018;97:670-683. e676.

[19]

Gergues MM, Han KJ, Choi HS, et al. Circuit and molecular architecture of a ventral hippocampal network. Nat Neurosci. 2020;23:1444-1452.

[20]

Jin J, Maren S. Fear renewal preferentially activates ventral hippocampal neurons projecting to both amygdala and prefrontal cortex in rats. Sci Rep. 2015;5:8388.

[21]

Chen HS, Zhang XL, Yang RR, et al. An intein-split transactivator for intersectional neural imaging and optogenetic manipulation. Nat Commun. 2022;13:3605.

[22]

de Jong JW, Afjei SA, Pollak Dorocic I, et al. A neural circuit mechanism for encoding aversive stimuli in the mesolimbic dopamine system. Neuron. 2019;101:133-151. e137.

[23]

Qiu S, Hu Y, Huang Y, et al. Whole-brain spatial organization of hippocampal single-neuron projectomes. Science. 2024;383:eadj9198.

RIGHTS & PERMISSIONS

2024 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

AI Summary AI Mindmap
PDF

119

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/