Concurrent DNA hypomethylation and epigenomic reprogramming driven by androgen receptor binding in bladder cancer oncogenesis

Yu Xiao; Lingao Ju; Wan Jin; Hongwei Peng; Zongning Zhou; Mengxue Yu; Zilin Xu; Gang Wang; Kaiyu Qian; Yi Zhang; Xinghuan Wang

doi:10.1002/ctm2.70153

Clinical and Translational Medicine ›› 2025, Vol. 15 ›› Issue (1) : e70153 DOI: 10.1002/ctm2.70153

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Concurrent DNA hypomethylation and epigenomic reprogramming driven by androgen receptor binding in bladder cancer oncogenesis

Yu Xiao ¹^,²
, Lingao Ju ²^,³
, Wan Jin ²^,⁴
, Hongwei Peng ²
, Zongning Zhou ²
, Mengxue Yu ²^,³
, Zilin Xu ²
, Gang Wang ¹^,²
, Kaiyu Qian ²^,³^,^†
, Yi Zhang ⁴^,⁵^,^†
, Xinghuan Wang ¹^,⁶^,⁷^,^†

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Yu Xiao, Lingao Ju, Wan Jin, Hongwei Peng, Zongning Zhou, Mengxue Yu, Zilin Xu, Gang Wang, Kaiyu Qian, Yi Zhang, Xinghuan Wang. Concurrent DNA hypomethylation and epigenomic reprogramming driven by androgen receptor binding in bladder cancer oncogenesis. Clinical and Translational Medicine, 2025, 15(1): e70153 DOI:10.1002/ctm2.70153

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2024 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.