The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome

Abstract

	•NLRP3 inflammasome activation is pivotal in mediating the excessive inflammatory response in ALI/ARDS.
	•Glycolytic reprogramming regulates NLRP3 inflammasome activation.
	•Therapeutic potential of targeting glycolytic reprogramming to inhibit NLRP3 inflammasome activation in ALI/ARDS.

Keywords

acute lung injury/acute respiratory distress syndrome / glycolytic reprogramming,macrophage / NLRP3 inflammasome

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