Disentangling the molecular mystery of tumour-microbiota interactions: Microbial metabolites

Yu-Fei Duan; Jia-Hao Dai; Ying-Qi Lu; Han Qiao; Na Liu

doi:10.1002/ctm2.70093

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (11) : e70093 DOI: 10.1002/ctm2.70093

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Disentangling the molecular mystery of tumour-microbiota interactions: Microbial metabolites

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Abstract

	•Metabolites derived from both gut and intratumoural microbiota play important roles in cancer initiation and progression.
	•The dual roles of microbial metabolites pose an obstacle for clinical translations.
	•Absolute quantification and tracing techniques of microbial metabolites are essential for addressing the gaps in studies on microbial metabolites.
	•Integrating microbial metabolomics with multi-omics transcends current research paradigms.

Keywords

cancer / functional mechanisms / microbial metabolites / microbial metabolomics

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Yu-Fei Duan, Jia-Hao Dai, Ying-Qi Lu, Han Qiao, Na Liu. Disentangling the molecular mystery of tumour-microbiota interactions: Microbial metabolites. Clinical and Translational Medicine, 2024, 14(11): e70093 DOI:10.1002/ctm2.70093

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2024 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.