A subtype of cancer-associated fibroblast expressing syndecan-2 (SDC2) predicts survival and immune checkpoint inhibitor response in gastric cancer

Ji-Yong Sung , Jae-Ho Cheong , Kihye Shin , Eui Tae Kim

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (12) : e70079

PDF
Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (12) : e70079 DOI: 10.1002/ctm2.70079
LETTER TO THE JOURNAL

A subtype of cancer-associated fibroblast expressing syndecan-2 (SDC2) predicts survival and immune checkpoint inhibitor response in gastric cancer

Author information +
History +
PDF

Cite this article

Download citation ▾
Ji-Yong Sung, Jae-Ho Cheong, Kihye Shin, Eui Tae Kim. A subtype of cancer-associated fibroblast expressing syndecan-2 (SDC2) predicts survival and immune checkpoint inhibitor response in gastric cancer. Clinical and Translational Medicine, 2024, 14(12): e70079 DOI:10.1002/ctm2.70079

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Lavie D, Ben-Shmuel A, Erez N, Scherz-Shouval R. Cancer-associated fibroblasts in the single-cell era. Nat Cancer. 2022; 3: 793-807.

[2]

Bader GD, Hogue CW. An automated method for finding molecular complexes in large protein interaction networks. BMC Bioinformatics. 2003; 4: 2.

[3]

Sung JY, Cheong JH. Prognosis-related gene signature is enriched in cancer-associated fibroblasts in the stem-like subtype of gastric cancer. Clin Transl Med. 2022; 12: e930.

[4]

Sung JY, Cheong JH. The Matrisome is associated with metabolic reprograming in stem-like phenotypes of gastric cancer. Cancers. 2022; 14(6): 1438.

[5]

Sung JY, Cheong JH. Gene signature related to cancer stem cells and fibroblasts of stem-like gastric cancer predicts immunotherapy response. Clin Transl Med. 2023; 13: e1347.

[6]

Jin S, Guerrero-Juarez CF, Zhang L, et al. Inference and analysis of cell-cell communication using CellChat. Nat Commun. 2021; 12: 1088.

[7]

Cheong JH, Yang HK, Kim H, et al. Predictive test for chemotherapy response in resectable gastric cancer: a multi-cohort, retrospective analysis. Lancet Oncol. 2018; 19: 629-638.

[8]

Pei L, Liu Y, Liu L, et al. Roles of cancer-associated fibroblasts (CAFs) in anti-PD-1/PD-L1 immunotherapy for solid cancers. Mol Cancer. 2023; 22: 29.

[9]

Sung JY, Cheong JH. Intercellular communications and metabolic reprogramming as new predictive markers for immunotherapy responses in gastric cancer. Cancer Commun (Lond). 2022; 42: 572-575.

[10]

Wang R, Song S, Qin J, et al. Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression. Cancer Cell. 2023; 41: 1407-1426.

RIGHTS & PERMISSIONS

2024 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

AI Summary AI Mindmap
PDF

128

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/