Confirmation of previously identified plasma microRNA ratios for breast cancer detection in a nested case-control study within a screening setting

Emir Sehovic; Ilaria Gregnanin; Maurizia Mello-Grand; Paola Ostano; Viviana Vergini; Andrea Ortale; Angela Amoruso; Elisabetta Favettini; Nereo Segnan; Giovanna Chiorino; Livia Giordano; Elisabetta Petracci

doi:10.1002/ctm2.70068

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (11) : e70068 DOI: 10.1002/ctm2.70068

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Confirmation of previously identified plasma microRNA ratios for breast cancer detection in a nested case-control study within a screening setting

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Emir Sehovic, Ilaria Gregnanin, Maurizia Mello-Grand, Paola Ostano, Viviana Vergini, Andrea Ortale, Angela Amoruso, Elisabetta Favettini, Nereo Segnan, Giovanna Chiorino, Livia Giordano, Elisabetta Petracci. Confirmation of previously identified plasma microRNA ratios for breast cancer detection in a nested case-control study within a screening setting. Clinical and Translational Medicine, 2024, 14(11): e70068 DOI:10.1002/ctm2.70068

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References

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[1]	Sehovic E, Urru S, Chiorino G, Doebler P. Meta-analysis of diagnostic cell-free circulating microRNAs for breast cancer detection. BMC Cancer. 2022;22:634.

[2]	Giordano L, Gallo F, Petracci E, Chiorino G, Segnan N, the Andromeda working group. The ANDROMEDA prospective cohort study: predictive value of combined criteria to tailor breast cancer screening and new opportunities from circulating markers: study protocol. BMC Cancer. 2017;17:785.

[3]	Chiorino G, Petracci E, Sehovic E, et al. Plasma microRNA ratios associated with breast cancer detection in a nested case-control study from a mammography screening cohort. Sci Rep. 2023;13:12040.

[4]	Koi Y, Tsutani Y, Nishiyama Y, et al. Predicting the presence of breast cancer using circulating small RNAs, including those in the extracellular vesicles. Cancer Sci. 2020;111:2104-2115.

[5]	Aggarwal V, Priyanka K, Tuli HS. Emergence of circulating MicroRNAs in breast cancer as diagnostic and therapeutic efficacy biomarkers. Mol Diagn Ther. 2020;24:153-173.

[6]	Deng Y, Zhu Y, Wang H, et al. Ratio-based method to identify true biomarkers by normalizing circulating ncRNA sequencing and quantitative PCR data. Anal Chem. 2019;91:6746-6753.

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2024 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.