Potential mechanisms of cancer stem-like progenitor T-cell bio-behaviours

Ling Ni

doi:10.1002/ctm2.1817

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (8) : e1817 DOI: 10.1002/ctm2.1817

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Potential mechanisms of cancer stem-like progenitor T-cell bio-behaviours

Ling Ni ^†

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Abstract

	•Tpex cells are located in lymph nodes and TLS.
	•Several pathways control the differentiation trajectories of Tpex cells, including epigenetic factors, transcription factors, cytokines, age, sex, etc.

Keywords

cancer / CD8 ⁺ T cells / immune checkpoint inhibitors / Tex-int cells / Tex-term cells / Tpex cells

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Ling Ni. Potential mechanisms of cancer stem-like progenitor T-cell bio-behaviours. Clinical and Translational Medicine, 2024, 14(8): e1817 DOI:10.1002/ctm2.1817

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2024 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.