Recent advances of PIWI-interacting RNA in cardiovascular diseases

Bo Li; Kai Wang; Wei Cheng; Bo Fang; Ying Hui Li; Su Min Yang; Mei Hua Zhang; Yun Hong Wang; Kun Wang

doi:10.1002/ctm2.1770

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (8) : e1770 DOI: 10.1002/ctm2.1770

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Recent advances of PIWI-interacting RNA in cardiovascular diseases

Bo Li ¹^,²
, Kai Wang ²
, Wei Cheng ³
, Bo Fang ²
, Ying Hui Li ²
, Su Min Yang ⁴
, Mei Hua Zhang ¹^,^†
, Yun Hong Wang ⁵^,^†
, Kun Wang ¹^,²^,^†

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Abstract

	•piRNA can be used as a potential therapeutic target and biomaker in CVDs.
	•piRNA influences apoptosis, inflammation and angiogenesis by regulating epigenetic modificaions.
	•Critical knowledge gaps remain in the unifying piRNA nomenclature and PIWI-independent function.

Keywords

biomarkers / CVDs / epigenetics / PIWI-interacting RNA

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Bo Li, Kai Wang, Wei Cheng, Bo Fang, Ying Hui Li, Su Min Yang, Mei Hua Zhang, Yun Hong Wang, Kun Wang. Recent advances of PIWI-interacting RNA in cardiovascular diseases. Clinical and Translational Medicine, 2024, 14(8): e1770 DOI:10.1002/ctm2.1770

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2024 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.