Plasma extrachromosomal circular DNA as a potential diagnostic biomarker for nodular thyroid disease

Meng Zhou; Wei Lv; Peng Han; Kai Sun; Ziqian Hao; Ling Gao; Yunyun Xu; Zhe Xu; Shanshan Shao; Shizhan Ma; Qingling Guo; Haiqing Zhang; Ke Liu; Fan Yang; Zhongshang Yuan; Guojun Wu; Changbin Yu; Yonglun Luo; Zhenyu Yao; Jiajun Zhao

doi:10.1002/ctm2.1740

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (6) : e1740 DOI: 10.1002/ctm2.1740

LETTER TO THE JOURNAL

Plasma extrachromosomal circular DNA as a potential diagnostic biomarker for nodular thyroid disease

Meng Zhou ¹^,²^,³
, Wei Lv ⁴
, Peng Han ⁵
, Kai Sun ⁶^,⁷^,⁸
, Ziqian Hao ⁶
, Ling Gao ¹^,²^,³
, Yunyun Xu ¹^,²^,³
, Zhe Xu ⁴
, Shanshan Shao ¹^,²^,³
, Shizhan Ma ¹^,²^,³
, Qingling Guo ¹^,²^,³
, Haiqing Zhang ¹^,²^,³
, Ke Liu ⁹
, Fan Yang ⁹
, Zhongshang Yuan ⁹
, Guojun Wu ¹⁰^,^†
, Changbin Yu ⁶^,^†
, Yonglun Luo ⁵^,^†
, Zhenyu Yao ¹^,²^,³^,^†
, Jiajun Zhao ¹^,²^,³^,^†

Author information +

¹. Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education, Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China

². Shandong Engineering Laboratory of Prevention and Control for Endocrine and Metabolic Diseases, Jinan, Shandong, China

³. Shandong Institute of Endocrine and Metabolic Disease, Jinan, Shandong, China

⁴. College of Life Sciences, University of Chinese Academy of Science, Beijing, China

⁵. Lars Bolund Institute of Regenerative Medicine, HIM-BGI Omics Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, China

⁶. College of Artificial Intelligence and Big Data for Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China

⁷. Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China

⁸. Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China

⁹. Department of Bio-statistics School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China

¹⁰. Department of Breast and Thyroid Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China

wuguojun@sdfmu.edu.cn

yu_lab@sdfmu.edu.cn

alun@biomed.au.dk

yaozhenyu@sdfmu.edu.cn

jjzhao@sdu.edu.cn

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Meng Zhou,Wei Lv,Peng Han,Kai Sun,Ziqian Hao,Ling Gao,Yunyun Xu,Zhe Xu,Shanshan Shao,Shizhan Ma,Qingling Guo,Haiqing Zhang,Ke Liu,Fan Yang,Zhongshang Yuan,Guojun Wu,Changbin Yu,Yonglun Luo,Zhenyu Yao,Jiajun Zhao. Plasma extrachromosomal circular DNA as a potential diagnostic biomarker for nodular thyroid disease. Clinical and Translational Medicine, 2024, 14(6): e1740 DOI:10.1002/ctm2.1740

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2024 The Author(s). Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.