Engineering exosomes to reshape the immune microenvironment in breast cancer: Molecular insights and therapeutic opportunities

Jilong Cao; Gang Lv; Fang Wei

doi:10.1002/ctm2.1645

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (4) : e1645 DOI: 10.1002/ctm2.1645

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Engineering exosomes to reshape the immune microenvironment in breast cancer: Molecular insights and therapeutic opportunities

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Abstract

Surface modification of exosomes can improve the targeting specificity.

The engineered exosome-loaded immunomodulatory cargo regulates the tumour immune microenvironment.

Engineered exosomes are involved in the immune regulation of breast cancer.

Keywords

breast cancer / engineered exosomes / immune microenvironment / immunomodulation / immunotherapy

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Jilong Cao,Gang Lv,Fang Wei. Engineering exosomes to reshape the immune microenvironment in breast cancer: Molecular insights and therapeutic opportunities. Clinical and Translational Medicine, 2024, 14(4): e1645 DOI:10.1002/ctm2.1645

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2024 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.