RNA methylation-related inhibitors: Biological basis and therapeutic potential for cancer therapy
Huanxiang Chen , Hongyang Liu , Chenxing Zhang , Nan Xiao , Yang Li , Xiangzhuan Zhao , Ruike Zhang , Huihui Gu , Qiaozhen Kang , Junhu Wan
Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (4) : e1644
RNA methylation-related inhibitors: Biological basis and therapeutic potential for cancer therapy
• In this paper, several important types of RNA modifications and their related regulatory factors are systematically summarised. • Several regulatory factors related to RNA modification types were associated with cancer progression, and their relationships with cancer cell migration, invasion, drug resistance and immune environment were summarised. • In this paper, the inhibitors targeting different regulators that have been proposed in recent studies are summarised in detail, which is of great significance for the development of RNA modification regulators and cancer treatment in the future.
cancer / drug resistance / inhibitor / RNA methylation
2024 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.
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