BCL11B promotes T-cell acute lymphoblastic leukaemia cell survival via the XRCC5/C11ORF21 axis

Xibao Yu; Yuchen Li; Pengyue Yang; Yan Wang; Xuan Liu; Letong Cai; Jing Lai; Yue Zhang; Xianfeng Zha; Grzegorz Krzysztof Przybylski; Ling Xu; Yangqiu Li

doi:10.1002/ctm2.1580

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (2) : e1580 DOI: 10.1002/ctm2.1580

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BCL11B promotes T-cell acute lymphoblastic leukaemia cell survival via the XRCC5/C11ORF21 axis

Xibao Yu ¹^,²^,³
, Yuchen Li ¹^,²
, Pengyue Yang ¹^,²
, Yan Wang ¹^,²
, Xuan Liu ¹^,²
, Letong Cai ¹^,²
, Jing Lai ¹
, Yue Zhang ¹
, Xianfeng Zha ⁴
, Grzegorz Krzysztof Przybylski ⁵
, Ling Xu ¹^,²^,^†
, Yangqiu Li ¹^,²^,^†

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Xibao Yu, Yuchen Li, Pengyue Yang, Yan Wang, Xuan Liu, Letong Cai, Jing Lai, Yue Zhang, Xianfeng Zha, Grzegorz Krzysztof Przybylski, Ling Xu, Yangqiu Li. BCL11B promotes T-cell acute lymphoblastic leukaemia cell survival via the XRCC5/C11ORF21 axis. Clinical and Translational Medicine, 2024, 14(2): e1580 DOI:10.1002/ctm2.1580

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References

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[1]	Longabaugh WJR, Zeng W, Zhang JA, et al. Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network. Proc Natl Acad Sci U S A. 2017;114:5800-5807.

[2]	Li P, Burke S, Wang J, et al. Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion. Science. 2010;329:85-89.

[3]	Li K, Chen C, Gao R, et al. Inhibition of BCL11B induces downregulation of PTK7 and results in growth retardation and apoptosis in T-cell acute lymphoblastic leukemia. Biomark Res. 2021;9:17.

[4]	Zhu H, Dong B, Zhang Y, et al. Integrated genomic analyses identify high-risk factors and actionable targets in T-cell acute lymphoblastic leukemia. Blood Sci. 2022;4:16-28.

[5]	Ma Q, Li P, Xu M, et al. Ku80 is highly expressed in lung adenocarcinoma and promotes cisplatin resistance. J Exp Clin Cancer Res. 2012;31:99.

[6]	Padella A, Luserna Di Rorà AG, Marconi G, Ghetti M, Martinelli G, Simonetti G. Targeting PARP proteins in acute leukemia: DNA damage response inhibition and therapeutic strategies. J Hematol Oncol. 2022;15:10.

[7]	Bhattacharjee S, Nandi S. Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer. Clin Transl Med. 2016;5:45.

[8]	Huang X, Chen S, Shen Q, et al. Down regulation of BCL11B expression inhibits proliferation and induces apoptosis in malignant T cells by BCL11B-935-siRNA. Hematology. 2011;16:236-242.

[9]	Zhu X, Higashimoto K, Soejima H, et al. C11orf21, a novel gene within the Beckwith-Wiedemann syndrome region in human chromosome 11p15.5. Gene. 2000;256:311-317.

[10]	Matsumoto A, Yoshida T, Shima T, et al. C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO. BBA Adv. 2022;2:100047.

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2024 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.