Rethinking nutritional villains: A trans-fatty acid identified to boost immunotherapy

Hao Fan , Freya Q. Zhang , Jing Chen

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (1) : e1537

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Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (1) : e1537 DOI: 10.1002/ctm2.1537
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Rethinking nutritional villains: A trans-fatty acid identified to boost immunotherapy

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CD8+ T cell / immunotherapy / trans-vaccenic acid

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Hao Fan, Freya Q. Zhang, Jing Chen. Rethinking nutritional villains: A trans-fatty acid identified to boost immunotherapy. Clinical and Translational Medicine, 2024, 14(1): e1537 DOI:10.1002/ctm2.1537

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References

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Fan H, Xia S, Xiang J, et al. Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity. Nature. 2023;623:1034-1043.

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Yakoob MY, Shi P, Willett WC, et al. Circulating biomarkers of dairy fat and risk of incident diabetes mellitus among men and women in the United States in two large prospective cohorts. Circulation. 2016;133:1645-1654.

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Kleber ME, Delgado GE, Lorkowski S, März Wvon Schacky C. Trans-fatty acids and mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health Study. Eur Heart J. 2016;37:1072-1078.

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Tian Z, Liu M, Zhang Y, Wang X. Bispecific T cell engagers: an emerging therapy for management of hematologic malignancies. J Hematol Oncol. 2021;14:75.

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2024 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

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