The rise of TIM-3: A promising immune target in diffuse midline gliomas

Iker Ausejo-Mauleon , Sara Nuin , Marta M. Alonso

Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (1) : e1536

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Clinical and Translational Medicine ›› 2024, Vol. 14 ›› Issue (1) : e1536 DOI: 10.1002/ctm2.1536
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The rise of TIM-3: A promising immune target in diffuse midline gliomas

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Iker Ausejo-Mauleon, Sara Nuin, Marta M. Alonso. The rise of TIM-3: A promising immune target in diffuse midline gliomas. Clinical and Translational Medicine, 2024, 14(1): e1536 DOI:10.1002/ctm2.1536

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References

[1]

Di Ruscio V, Del Baldo G, Fabozzi F, et al. Pediatric diffuse midline gliomas: an unfinished puzzle. Diagnostics. 2022;12(9):2064.

[2]

El-Khouly FE, Veldhuijzen van Zanten SEM, Santa-Maria LopezV, et al. Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand? J Neurooncol. 2019;145(1):177-184.

[3]

Ausejo-Mauleon I, Labiano S, de la Nava D, et al. TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory. Cancer Cell.41(11):1911-1926.e8.

[4]

Kline C, John-Liu S, Duriseti S, et al. Reirradiation and PD-1 inhibition with nivolumab for the tratment of recurrent diffuse intrinsic pontine glioma: a single-institution experience. J Neurooncol. 2018;140(3):629-638.

[5]

Persson ML, Douglas AM, Alvaro F, et al. The intrinsic and microenvironmental features of diffuse midline glioma: implications for the development of effective immunotherapeutic treatment strategies. Neuro Oncol. 2022;24(9):1408-1422.

[6]

Lieberman NAP, Degolier K, Kovar HM, et al. Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: implications for development of immunotherapy. Neuro Oncol. 2019;21(1):83-94.

[7]

Lin GL, Nagaraja S, Filbin MG, et al. Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma. Acta Neuropathol Commun. 2018;6(1):51.

[8]

Gállego Pérez-Larraya J, Garcia-Moure M, Labiano S, et al. Oncolytic DNX-2401 virus for pediatric diffuse intrinsic pontine glioma. N Engl J Med. 2022;386(26):2471-2481.

[9]

Laspidea V, Puigdelloses M, Labiano S, et al. Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas. JCI Insight. 2022;7(7):e154812.

[10]

Martínez-Vélez N, Garcia-Moure M, Marigil M, et al. The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models. Nat Commun. 2019;10(1):2235.

[11]

Majzner RG, Ramakrishna S, Yeom KW, et al. GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas. Nature. 2022;603(7903):934-941.

[12]

Mount CW, Majzner RG, Sundaresh S, et al. Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas letter. Nat Med. 2018;24(5):572-579.

[13]

Vitanza NA, Wilson AL, Huang W, et al. Intraventricular B7-H3 CAR T cells for diffuse intrinsic pontine glioma: preliminary first-in-2 human bioactivity and safety. Cancer Discov.13(1):114-131.

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2024 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

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