A case of multiple pulmonary nodules diagnosed as pulmonary melanoma without extra-pulmonary site

Yoshihiro Miyashita; Miyuki Kobayashi; Yumiko Kakizaki; Toshiharu Tsutsui; Takashi Kumagai; Hiroaki Kobayashi; Haruna Yamaki; Chisa Ohmori; Toshio Oyama

doi:10.5430/crim.v8n1p1

Case Reports in Internal Medicine ›› 2021, Vol. 8 ›› Issue (1) :1 -4. DOI: 10.5430/crim.v8n1p1

CASE REPORTS

research-article

A case of multiple pulmonary nodules diagnosed as pulmonary melanoma without extra-pulmonary site

Author information +

History +

PDF (354KB)

Abstract

A 67-year-old patient visited the hospital for the evaluation of pulmonary nodular lesions detected in his chest radiograph during an annual screening. He was asymptomatic and transbronchial tumor biopsy of the nodule in the right upper lobe revealed features of pulmonary sarcoma, which did not resemble any of the histolopathological categories of primary lung cancer. A positive immunological staining for both HMB-45 and Melan-A resulted in the final diagnosis of melanoma. It is important for a respiratory clinician to remind the possibility of a melanoma, when tumors cannot be histopathologically classified under any of the categories of primary lung cancer.

Keywords

Malignant melanoma / Pulmonary nodule / Metastatic

Cite this article

Download citation ▾

Yoshihiro Miyashita, Miyuki Kobayashi, Yumiko Kakizaki, Toshiharu Tsutsui, Takashi Kumagai, Hiroaki Kobayashi, Haruna Yamaki, Chisa Ohmori, Toshio Oyama. A case of multiple pulmonary nodules diagnosed as pulmonary melanoma without extra-pulmonary site. Case Reports in Internal Medicine, 2021, 8(1): 1-4 DOI:10.5430/crim.v8n1p1

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Dountsis A, Zisis C, Karagianni E, et al. Primary Malignant Melanoma of the Lung: A Case Report. World J Surg Oncol. 2003; 1(1): 26. PMid:14750982. https://doi.org/10.1186/1477-7819-1-26

[2]	Shi Y, Bing Z, Xu X, et al. Primary pulmonary malignant melanoma: Case report and literature review. Thorac Cancer. 2018; 9(9): 1185-1189. PMid:30062692. https://doi.org/10.1111/1759-7714.12798

[3]	Kyriakopoulos C, Zarkavelis G, Andrianopoulou A, et al. Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review. Case Rep Oncol Med. 2017; 2017: 8654326. PMid:28352484. https://doi.org/10.1155/2017/8654326

[4]	Seitelman E, Donenfeld P, Kay K, et al. Successful treatment of primary pulmonary melanoma. J Thorac Dis. 2011 ; 3(3): 207-208.

[5]	Tina T, Helle K, Krzysztof TD. Extensive screening for primary tumor is redundant in melanoma of unknown primary. J Surg Oncol. 2011; 104(7): 724-727. PMid:21721009. https://doi.org/10.1002/jso.21994

[6]	Yun S, Vincelette ND, Green MR, et al. Targeting immune checkpoints in unresectable metastatic cutaneous melanoma: a systematic review and meta-analysis of anti-CTLA-4 and anti-PD-1 agents trials. Cancer Med. 2016; 5(7): 1481-1491. PMid:27167347. https://doi.org/10.1002/cam4.732