Autoimmune polyendocrine syndrome type II: After adrenal crisis

Nuno Zarcos Palma; Mariana da Cruz; Lígia Rodrigues dos Santos; Margarida Cruz; Filipe Cunha; Vítor Fagundes; Lindora Pires; Mari Mesquita

doi:10.5430/crim.v7n2p3

Case Reports in Internal Medicine ›› 2020, Vol. 7 ›› Issue (2) :3 -6. DOI: 10.5430/crim.v7n2p3

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Autoimmune polyendocrine syndrome type II: After adrenal crisis

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Abstract

Autoimmune Polyendocrine Syndromes (APS) are rare autoimmune endocrinopathies, characterized by the association of two or more organ-specific disorders. Type II Autoimmune Polyendocrine Syndromes (APS II) comprises the association of Addison’s disease with thyroid autoimmune disease and/or type 1 diabetes mellitus. Although the classic presentation is symptomatic hypotension, it can manifest as an adrenal crisis - a life-threatening condition. We report a case of a 41-year-old woman with prolonged asthenia, cutaneous hyperpigmentation and symptomatic hypotension refractory to intravenous fluids. APS II was diagnosed with a presentation of an Addisonian crisis, resolved after the onset of hydrocortisone.

Keywords

Adrenal crisis / Addison’s disease / Autoimmune Polyendocrine Syndrome / Schmidt’s syndrome / Carpenter’s Syndrome

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Nuno Zarcos Palma, Mariana da Cruz, Lígia Rodrigues dos Santos, Margarida Cruz, Filipe Cunha, Vítor Fagundes, Lindora Pires, Mari Mesquita. Autoimmune polyendocrine syndrome type II: After adrenal crisis. Case Reports in Internal Medicine, 2020, 7(2): 3-6 DOI:10.5430/crim.v7n2p3

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