Lactate-Induced Liquid–Liquid Phase Separation of HIF-1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer

Chenhao Fu; Xiang Chen; Haoyu Huang; Lipeng Zhang; Haonan Huang; Fan Jiang; Fayang Lei; Honglong Yu; Jibiao Liu; Houping Zhang; Kan Dai; Zhixiong Wu; Huizi Li; Xi-jian Dai; Shengxun Mao

doi:10.1111/cpr.70212

Cell Proliferation ›› 2026, Vol. 59 ›› Issue (6) :e70212 DOI: 10.1111/cpr.70212

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Lactate-Induced Liquid–Liquid Phase Separation of HIF-1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer

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Chenhao Fu, Xiang Chen, Haoyu Huang, Lipeng Zhang, Haonan Huang, Fan Jiang, Fayang Lei, Honglong Yu, Jibiao Liu, Houping Zhang, Kan Dai, Zhixiong Wu, Huizi Li, Xi-jian Dai, Shengxun Mao. Lactate-Induced Liquid–Liquid Phase Separation of HIF-1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer. Cell Proliferation, 2026, 59 (6) : e70212 DOI:10.1111/cpr.70212

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References

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