MXene-Based Functional Platforms for Diabetes Prevention and Treatment

Abstract

In recent years, a class of 2D transition metal carbides, nitrides, and carbonitrides (MXenes) has demonstrated outstanding advantages in the field of diabetes treatment, particularly in constructing the functional platforms for optimal diabetes treatment, owing to their excellent electrical conductivity, abundant functional groups, large specific surface area, unique photothermal effect, and biocompatibility. This review summarizes the unique advantages and latest progress of MXene-based approaches for the prevention and treatment of diabetes. The significant assistance of MXenes in various therapeutic stages of diabetes, including their application in noninvasive blood glucose monitoring, as well as the implementation strategies of MXenes in wound healing and complication management for diabetic patients, is discussed in detail. Furthermore, the key clinical translational barriers and regulatory issues for advancing MXene-based diabetes treatment platforms are discussed. Finally, the existing challenges and future development directions of MXene materials in diabetes treatment are summarized and prospectively discussed.

Keywords

antidiabetic drugs/compounds / clinical transformation / functional effects / MXenes / nanobiomaterials

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