Research Progress on Radiation Volt-Effect Isotope Cells

Abstract

Radioisotope batteries, as a highly efficient and long-lasting micro-energy conversion technology, demonstrate unique advantages in fields, such as aerospace, medical devices, and power supply in extreme environments. This paper provides a systematic review of the research progress in radioisotope batteries, with a focus on analyzing the performance of different semiconductor materials in terms of energy conversion efficiency, radiation resistance, and application potential. The content covers optimization strategies and application prospects for traditional and wide/ultra-wide bandgap semiconductor materials (including silicon, gallium arsenide, silicon carbide, gallium nitride, titanium dioxide, zinc oxide, diamond, gallium oxide, and perovskite, among others). It also identifies current technical challenges, including low energy conversion efficiency, accelerated performance degradation of semiconductor materials under irradiation, and challenges related to the safe management of radioisotope. Finally, the article outlines future research directions, emphasizing the promotion of practical applications of radioisotope batteries through material innovation, structural design, and process optimization, with the aim of advancing academic innovation and engineering practices to address extreme environmental conditions and long-term energy demands.

Keywords

betavoltaic cell / energy conversion material / radioisotope batteries / wide bandgap semiconductor

References

[1] C. E. Munson, Q. Gaimard, K. Merghem, et al., “Modeling, Design, Fabrication and Experimentation of a GaN-based,63Ni Betavoltaic Battery,” Journal of Physics D: Applied Physics 51 (2018): 035101.

[2] F. Urbani, G. Squadrito, O. Barbera, G. Giacoppo, E. Passalacqua, and O. Zerbinati, “Polymer Electrolyte Fuel Cell Mini Power Unit for Portable Application,” Journal of Power Sources 169 (2007): 334–337.

[3] R. Deng, B. Ke, Y. Xie, et al., “All-solid-State Thin-Film Lithium-Sulfur Batteries,” NanomicroLetters 15, no. 1 (2023): 73.

[4] M. Saravanapavanantham, J. Mwaura, and V. Bulović, “Printed Organic Photovoltaic Modules on Transferable Ultra-Thin Substrates as Additive Power Sources,” Small Methods 7, no. 1 (2023): 2200940.

[5] P. Rappaport, “The Electron-Voltaic Effect in p−n Junctions Induced by Beta-Particle Bombardment,” Physical Review 93 (1954): 246–247.

[6] L. C. Olsen, “Betavoltaic Energy Conversion,” Energy Conversion 13 (1973): 117–127.

[7] H. Guo, H. Yang, and Y. Zhang, 2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS) (IEEE, 2007), 867–870.

[8] V. P. Khvostikov, V. S. Kalinovskii, S. V. Sorokina, O. A. Khvostikova, and V. M. Andreev, “Tritium Power Supply Sources Based on AlGaAs/GaAs Heterostructures,” Technical Physics Letters 45, no. 12 (2019): 1197–1199.

[9] M. V. S. Chandrashekhar, C. I. Thomas, H. Li, M. G. Spencer, and A. Lal, “Tritium Power Supply Sources Based on AlGaAs/GaAs Heterostructures,” Applied Physics Letters 88 (2006).

[10] H. Guo, Y. Shi, Y. Zhang, Y. Zhang, and J. Han, “ Demonstration of a 4H SiC Betavoltaic Cell,” in 2011 IEEE International Conference of Electron Devices and Solid-State Circuits (IEEE, 2011), 1–2.

[11] R. Gao, W. Ma, P. Wan, et al., “Fabrication of SiC Pin Betavoltaic Cell with 63 Ni Irradiation Source,” Energy & Environmental Materials 8 (2025).

[12] M. Lu, G. Zhang, K. Fu, G. Yu, D. Su, and J. Hu, “Gallium Nitride Schottky Betavoltaic Nuclear Batteries,” Energy Conversion and Management 52 (2011): 1955–1958.

[13] Z.-J. Cheng, H.-S. San, X.-Y. Chen, B. Liu, and Z.-H. Feng, “Demonstration of a High Open-Circuit Voltage GaN Betavoltaic Microbattery,” Chinese Physics Letters 28 (2011): 078401.

[14] C. E. Munson, M. Arif, J. Streque, et al., “Model of Ni-63 Battery With Realistic PIN Structure,” Journal of Applied Physics 118, no. 10 (2015): 105101.

[15] R. Gao, L. Liu, X. Xia, et al., “Isoelectronic Aluminum-Doped Gallium Nitride Alpha-Voltaic Cell With Efficiency Exceeding 4.5,” Communications Materials 4 (2023): 50.

[16] V. S. Bormashov, S. Y. Troschiev, S. A. Tarelkin, et al., “High Power Density Nuclear Battery Prototype Based on Diamond Schottky Diodes,” Diamond and Related Materials 84 (2018): 41–47.

[17] V. Bormashov, S. Troschiev, A. Volkov, et al., “Development of Nuclear Microbattery Prototype Based on Schottky Barrier Diamond Diodes,” Physica Status Solidi (a) 212 (2015): 2539–2547.

[18] X. Han, Z. Wang, F. Cao, P. Qu, P. Jin, and Z. Wang, “Diamond Schottky Barrier Diode Energy Converter Working Under~mA Output for Nuclear Batteries,” ACS Applied Electronic Materials 6, no. 12 (2024): 8849–8854.

[19] G. Li, C. Zhao, Y. Liu, et al., “High-Performance Perovskite Betavoltaics Employing High-Crystallinity MAPbBr₃ Films,” ACS Omega 6 (2021): 20015–20025.

[20] R. Gao, R. Chen, P. Wan, et al., “High Efficiency Formamidinium-Cesium Perovskite-Based Radio-Photovoltaic Cells,” Energy & Environmental Materials 7, no. 1 (2024): e12513.

[21] K. Li, C. Yan, J. Wang, et al., “Micronuclear Battery Based on a Coalescent Energy Transducer,” Nature 633, no. 8031 (2024): 811–815.

[22] F. K. Manasse, J. J. Pinajian, and A. N. Tse, “Schottky Barrier Betavoltaic Battery,” IEEE Transactions on Nuclear Science 23 (1976): 860–870.

[23] J. Yang, C. Fares, Y. Guan, et al., “10 MeV Proton Damage in β-Ga2O3 Schottky Rectifiers,” Journal of Vacuum Science & Technology B, Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena 36, no. 1 (2018): 011206.

[24] J. Kim, S. J. Pearton, C. Fares, et al., “Radiation Damage Effects in Ga₂O₃ Materials and Devices,” Journal of Materials Chemistry C 7 (2019): 10–24.

[25] A. R. Kirmani, T. A. Byers, Z. Ni, et al., “Unraveling Radiation Damage and Healing Mechanisms in Halide Perovskites Using Energy-Tuned Dual Irradiation Dosing,” Nature Communications 15 (2024): 696.

[26] D.-Y. Qiao, X.-J. Chen, Y. Ren, and W.-Z. Yuan, “A Micro Nuclear Battery Based on SiC Schottky Barrier Diode,” Journal of Microelectromechanical Systems 20 (2011): 685–690.

[27] N. F. Mott, “The Transition to the Metallic State,” Philosophical Magazine 6 (1961): 287–309.

[28] W. G. Pfann and W. Van Roosbroeck, “Radioactive and Photoelectricp-Njunction Power Sources,” Journal of Applied Physics 25 (1954): 1422–1434.

[29] M. Lewis and S. E. Seeman, “Performance Experience With Prototype Betacel Nuclear Batteries,” Nuclear Technology 17 (1973): 160–167.

[30] L. C. Olsen, Lewis Research Center, “ Review of Betavoltaic Energy Conversion,” in Proceedings of the 12th Space Photovoltaic Research and Technology Conference (SPRAT 12) (NASA, 1993), 256–267.

[31] P. Liu, Y. Chang, and J. Zhang, “Single-Walled Carbon Nanotube Film-Silicon Heterojunction Radioisotope Betavoltaic Microbatteries,” Journal of Micromechanics and Microengineering 24 (2014): 055026.

[32] X. Tang, D. Ding, Y. Liu, and D. Chen, “Optimization Design and Analysis of Si-⁶³Ni Betavoltaic Battery,” Science China: Technological Sciences 55 (2012): 990–996.

[33] K. Wu, C. Dai, and H. Guo, “ A theoretical Study on Silicon Betavoltaics Using Ni-63,” in 2011 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE, 2011), 724–727.

[34] J. Chu, “Research of Radioisotope Microbattery Based on β-radio-Voltaic Effect,” Journal of Micro/Nanolithography, MEMS, and MOEMS 8 (2009): 021180.

[35] J. Wang, P. Jin, P. L. Bishop, and F. Li, “Upgrade of Three Municipal Wastewater Treatment Lagoons Using a High Surface Area Media,” Frontiers of Environmental Science & Engineering 6 (2012): 288–293.

[36] L. Sun, W. Yuan, D. Qiao, and C. Qin, “Design and Simulation of a Novel Radioisotope Micro Battery Based on MEMS,” Chinese Journal of Sensors and Actuators 19 (2006): 997–1000.

[37] S. Deus, “ Tritium-Powered Betavoltaic Cells Based on Amorphous Silicon,” in Conference Record of the Twenty-Eighth IEEE Photovoltaic Specialists Conference-2000 (Cat. No.00CH37036), (IEEE, 2000), 1246–1249.

[38] J. Blanchard, D. Henderson, and A. Lal, Nuclear Microbattery for MEMS Devices, Nasa Sti/Recon Technical Report N (2001): 3.

[39] H. Guo and A. Lal, “TRANSDUCERS ’03,” in 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664), (IEEE, 2003), 36–39.

[40] J. Guo, X. Liu, J. Yu, et al., “An Overview of The Comprehensive Utilization of Silicon-Based Solid Waste Related to PV Industry,” Resources, Conservation and Recycling 169 (2021): 105450.

[41] L. Shen, S. Li, Y. Wang, et al., “Upcycling Photovoltaic Silicon Waste Into Cost-Effectiveness Si/C Anode Materials,” Carbon Energy 7, no. 7 (2025): e70004.

[42] J. Lu, J. Liu, X. Gong, et al., “Upcycling of Photovoltaic Silicon Waste Into Ultrahigh Areal-Loaded Silicon Nanowire Electrodes Through Electrothermal Shock,” Energy Storage Materials 46 (2022): 594–604.

[43] L. Shen, K. Sun, F. Xi, et al., “Conversion of Photovoltaic Waste Silicon Into Amorphous Silicon Nanowire Anodes,” Energy & Environmental Science 18 (2025): 4348–4361.

[44] J. Lu, S. Liu, J. Liu, et al., “Millisecond Conversion of Photovoltaic Silicon Waste to Binder-Free High Silicon Content Nanowires Electrodes,” Advanced Energy Materials 11, no. 40 (2021): 2102103.

[45] H. Flicker, J. J. Loferski, and T. S. Elleman, “Construction of a Promethium-147 Atomic Battery,” IEEE Transactions on Electron Devices 11 (1964): 2–8.

[46] G. N. Yakubova, Urbana (University of Illinois, 2010).

[47] H. Chen, L. Jiang, and X. Chen, “Design Optimization of GaAs Betavoltaic Batteries,” Journal of Physics D: Applied Physics 44 (2011): 215303.

[48] R. Zheng, J. Lu, Y. Wang, et al., “Enhanced Performance of GaAs-Based Betavoltaic Batteries by Using AlGaAs Hole/Electron Transport Layers,” Journal of Physics D: Applied Physics 55 (2022): 304002.

[49] M. V. Dorokhin, O. V. Vikhrova, P. B. Demina, et al., “GaAs Diodes for TiT₂-based Betavoltaic Cells,” Applied Radiation and Isotopes 179 (2022): 110030.

[50] D.-R. Li, L. Jiang, J.-H. Yin, Y.-Y. Tan, and N. Lin, “Betavoltaic Battery Conversion Efficiency Improvement Based on Interlayer Structures,” Chinese Physics Letters 29 (2012): 078102.

[51] S. Butera, G. Lioliou, and A. M. Barnett, “Temperature Effects on Gallium Arsenide 63 Ni Betavoltaic Cell,” Applied Radiation and Isotopes 125 (2017): 42–47.

[52] V. M. Andreev, A. G. Kevetsky, V. S. Kaiinovsky, et al., “ Tritium-Powered Betacells Based on Al_xGa₁-_xAs,” in Conference Record of the Twenty-Eighth IEEE Photovoltaic Specialists Conference-2000 (Cat. No.00CH37036) (IEEE, 2000), 1253–1256.

[53] L. Fu, J. Li, G. Wang, Y. Luan, and W. Dai, “Adsorption Behavior of Organic Pollutants on Microplastics,” Ecotoxicology and Environmental Safety 217 (2021): 112207.

[54] C. Qian, H. Guo, C. Han, H. Yuan, Y. Zhang, and Y. Zhang, “Design of High-Efficiency SiC Betavoltaic Battery Structures With Reduced Impact of Near-Surface Recombination Based on Accurate Modeling,” IEEE Transactions on Electron Devices 69 (2022): 7141–7146.

[55] X. Y. Li, Y. Ren, X. J. Chen, D. Y. Qiao, and W. Z. Yuan, “63Ni Schottky Barrier Nuclear Battery of 4H-SiC,” Journal of Radioanalytical and Nuclear Chemistry 287 (2011): 173–176.

[56] C. Thomas, S. Portnoff, and M. G. Spencer, “High Efficiency 4H-SiC Betavoltaic Power Sources Using Tritium Radioisotopes,” Applied Physics Letters 108, no. 1 (2016): 013505.

[57] R. Zheng, J. Lu, Y. Liu, et al., “Comparative Study of GaN Betavoltaic Battery Based on pn Junction and Schottky Barrier Diode,” Radiation Physics and Chemistry 168 (2020): 108595.

[58] M. G. Cheong, K. S. Kim, C. S. Oh, et al., “Conductive Layer Near the GaN/Sapphire Interface and Its Effect on Electron Transport in Unintentionally Doped n-Type GaN Epilayers,” Applied Physics Letters 77 (2000): 2557–2559.

[59] D. C. Look and R. J. Molnar, “Degenerate Layer at GaN/Sapphire Interface: Influence on Hall-Effect Measurements,” Applied Physics Letters 70 (1997): 3377–3379.

[60] Z. Cheng, X. Chen, H. San, Z. Feng, and B. Liu, “A High Open-Circuit Voltage Gallium Nitride Betavoltaic Microbattery,” Journal of Micromechanics and Microengineering 22 (2012): 074011.

[61] A. Toprak, D. Yılmaz, and E. Özbay, “A Study on GaN-Based Betavoltaic Batteries,” Semiconductor Science and Technology 37 (2022): 125005.

[62] M. T. Noman, M. A. Ashraf, and A. Ali, “Synthesis and Applications of nano-TiO₂: A Review,” Environmental Science and Pollution Research 26 (2019): 3262–3291.

[63] A. M. Ruiz, G. Sakai, A. Cornet, K. Shimanoe, J. R. Morante, and N. Yamazoe, “Microstructure Control of Thermally Stable TiO₂ Obtained by Hydrothermal Process for Gas Sensors,” Sensors and Actuators B: Chemical 103 (2004): 312–317.

[64] C. He, X. Z. Li, N. Graham, and Y. Wang, “Preparation of TiO₂/ITO and TiO₂/Ti Photoelectrodes by Magnetron Sputtering for Photocatalytic Application,” Applied Catalysis, A: General 305 (2006): 54–63.

[65] K. Lee, A. Mazare, and P. Schmuki, “One-Dimensional Titanium Dioxide Nanomaterials: Nanotubes,” Chemical Reviews 114 (2014): 9385–9454.

[66] N. Wang, Y. Ma, J. Chen, et al., “Defect-Induced Betavoltaic Enhancement in Black Titania Nanotube Arrays,” Nanoscale 10 (2018): 13028–13036.

[67] Y. Ma, N. Wang, J. Chen, et al., “Betavoltaic Enhancement Using Defect-Engineered TiO₂ Nanotube Arrays Through Electrochemical Reduction in Organic Electrolytes,” ACS Applied Materials & Interfaces 10 (2018): 22174–22181.

[68] J.-Y. Lee, J. Park, and J.-H. Cho, Applied Physics Letters 87, no. 1 (2005): 011904.

[69] E. L. Boytsova, L. A. Leonova, and V. F. Pichugin, “The Structure of Biocoats Based on TiO₂ Doped With Nitrogen Study,” IOP Conference Series: Materials Science and Engineering 347 (2018): 012025.

[70] C. Li, Y. Hsieh, W. Chiu, C. Liu, and C. Kao, “Study on Preparation and Photocatalytic Performance of Ag/TiO₂ and Pt/TiO₂ Photocatalysts,” Separation and Purification Technology 58 (2007): 148–151.

[71] Z. Ding, T.-X. Jiang, R.-R. Zheng, et al., “Quantitative Modeling, Optimization, and Verification of ⁶³Ni-Powered Betavoltaic Cells Based on Three-Dimensional ZnO Nanorod Arrays,” Nuclear Science and Techniques 33 (2022): 144.

[72] Z. Movahedian and H. Tavakoli-Anbaran, “Experimental and Theoretical Study of ⁹⁰Sr/⁹⁰Y-n-Si/ZnO Betavoltaic Battery and Theoretical Prediction of Homojunction Betavoltaic Cells Performance,” Materials Science in Semiconductor Processing 186 (2025): 109059.

[73] M. Maghsodi and H. Tavakoli-Anbaran, “ZnO Betavoltaic Batteries: Exploring Cylindrical Designs for Maximum Efficiency and Output,” Arabian Journal for Science and Engineering 50 (2025): 1–15.

[74] Z. Movahedian and H. Tavakoli-Anbaran, “Exploratory Study of Betavoltaic Nuclear Battery Using AlN PN Junction,” Journal of Energy Storage 72 (2023): 108485.

[75] B. Liu, K. Liu, V. Ralchenko, et al., “Effect of Americium-241 Source Activity on Total Conversion Efficiency of Diamond Alpha-Voltaic Battery,” International Journal of Energy Research 43 (2019): 6038–6044.

[76] B. Liu, K. Liu, J. Zhao, et al., “Enhanced Performance of Diamond Schottky Nuclear Batteries by Using ZnO as Electron Transport Layer,” Diamond and Related Materials 109 (2020): 108026.

[77] Shivani , D. Kaur, A. Ghosh, and M. Kumar, “A Strategic Review on Gallium Oxide Based Power Electronics: Recent Progress and Future Prospects,” Materials Today Communications 33 (2022): 104244.

[78] Z. Wang, G. Zhang, X. Zhang, et al., “Polarization-Sensitive Artificial Optoelectronic Synapse Based on Anisotropic β-Ga₂O₃ Single Crystal for Neuromorphic Vision Systems and Information Encryption,” Advanced Optical Materials 12, no. 29 (2024): 2401256.

[79] C. Wu, F. Wu, H. Hu, S. Wang, A. Liu, and D. Guo. “Review of Self-Powered Solar-Blind Photodetectors Based on Ga₂O₃,” Materials Today Physics 28 (2022): 100883.

[80] M. R. Lorenz, J. F. Woods, and R. J. Gambino, “Some Electrical Properties of the Semiconductor β-Ga₂O₃,” Journal of Physics and Chemistry of Solids 28 (1967): 403–404.

[81] N. Ma, N. Tanen, A. Verma, et al., “Intrinsic Electron Mobility Limits in β-Ga₂O₃,” Applied Physics Letters 109, no. 21 (2016): 212101.

[82] M. Higashiwaki, H. Murakami, Y. Kumagai, and A. Kuramata, “Current Status of Ga₂O₃ Power Devices,” Japanese Journal of Applied Physics 55 (2016): 1202A1.

[83] S. J. Pearton, J. Yang, P. H. Cary, et al., “A Review of Ga₂O₃ Materials, Processing, and Devices,” Applied Physics Review 5, no. 1 (2018): 011301.

[84] J. Zhang, J. Willis, Z. Yang, et al., “Direct Determination of Band-Gap Renormalization in Degenerately Doped Ultrawide Band Gap β-Ga₂O₃ Semiconductor,” Physical Review B 106 (2022): 205305.

[85] M. A. Mastro, A. Kuramata, J. Calkins, J. Kim, F. Ren, and S. J. Pearton, “Perspective—Opportunities and Future Directions for Ga₂O₃,” ECS Journal of Solid State Science and Technology 6 (2017): P356–P359.

[86] X. Liu, S. Lu, and M. Xia, “Advances in High-Energy Irradiation Stability and Damage Mechanisms of Perovskite Materials,” Chin J Lum 46 (2025): 642–657.

[87] W. Chen, Y. Liu, Z. Yuan, et al., “X-Ray Radioluminescence Effect of All-Inorganic Halide Perovskite CsPbBr₃ Quantum Dots,” Journal of Radioanalytical and Nuclear Chemistry 314 (2017): 2327–2337.

[88] W. Chen, X. Tang, Y. Liu, et al., “Novel Radioluminescent Nuclear Battery: Spectral Regulation of Perovskite Quantum Dots,” International Journal of Energy Research 42 (2018): 2507–2517.

[89] Z. Xu, X. Tang, Y. Liu, et al., “CsPbBr₃ Quantum Dot Films With High Luminescence Efficiency and Irradiation Stability for Radioluminescent Nuclear Battery Application,” ACS Applied Materials & Interfaces 11 (2019): 14191–14199.

[90] Z. Xu, Y. Liu, and X. Tang, “Radioluminescent Nuclear Battery Technology Development for Space Exploration,” Advances in Astronautics Science and Technology 3 (2020): 125–131.

[91] W. Xiong, W. Tang, G. Zhang, et al., “Controllable p- and n-Type Behaviours in Emissive Perovskite Semiconductors,” Nature 633 (2024): 344–350.

[92] V. Milotti, S. Cacovich, D. R. Ceratti, et al., “Degradation and Self-Healing of FAPbBr₃ Perovskite Under Soft-X-Ray Irradiation,” Small Methods 7, no. 9 (2023): 2300222.

[93] Z. Liao, Z. Xiao, M. Yang, et al., “Direct Imaging of Carrier Diffusion Length in Organic-Inorganic Perovskites,” Applied Physics Letters 115, no. 24 (2019): 242104.

[94] J. Ding, Z. Lian, Y. Li, S. Wang, and Q. Yan, “The Role of Surface Defects in Photoluminescence and Decay Dynamics of High-Quality Perovskite MAPbI₃ Single Crystals,” Journal of Physical Chemistry Letters 9 (2018): 4221–4226.

[95] R. Li, B. Li, X. Fang, et al., “Self-Structural Healing of Encapsulated Perovskite Microcrystals for Improved Optical and Thermal Stability,” Advanced Materials 33, no. 21 (2021): 2100466.

[96] Q. Li, Y. Zheng, H. Wang, et al., “Graphene-Polymer Reinforcement of Perovskite Lattices for Durable Solar Cells,” Science 387 (2025): 1069–1077.

[97] Y. Naghipour and M. Amirmazlaghani, “Graphene/Porous GaN Schottky Betacell,” Micro and Nanostructures 168 (2022): 207323.

[98] M. Amirmazlaghani, A. Rajabi, Z. Pour-mohammadi, and A. A. Sehat, “Betavoltaic Battery Based on Reduced-Graphene-Oxide/Si Heterojunction,” Superlattices and Microstructures 145 (2020): 106602.

[99] X. Wang, Y. Han, J. Zhang, et al., “The Design of a Direct Charge Nuclear Battery With High Energy Conversion Efficiency,” Applied Radiation and Isotopes 148 (2019): 147–151.

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