Metabolic mechanism of astaxanthin biosynthesis in Xanthophyllomyces dendrorhous in response to sodium citrate treatment

Abstract

•	Na-citrate treatment significantly increases biomass and astaxanthin yield in X. dendrorhous.
•	Na-citrate treatment enhances the glycolysis pathway in X. dendrorhous.
•	Na-citrate treatment downregulates TCA cycle-associated metabolites in X. dendrorhous.
•	Na-citrate treatment improves the transcription levels of key genes associated with astaxanthin biosynthesis.
•	Exogenous Na-citrate treatment is a potential regulatory model for astaxanthin biosynthesis in X. dendrorhous

Keywords

Xanthophyllomyces dendrorhous / Astaxanthin / Na-citrate / Metabolomics / Gene expression

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Funding

National Natural Science Foundation of China(32200047)

Key Program of Anhui Province Education Department(KJ2021A0711)

College of Agriculture Science and Natural Resources, Institute of Agriculture and Natural Resources(2020byzd025)