Ionic liquid-based multi-stage sugaring-out extraction of lactic acid from simulated broth and actual lignocellulosic fermentation broth

Xu Zhou , Yaqin Sun , Hongjun Zhan , Haijun Liu , Xiaoyan Wang , Yang Xu , Yi Li , Zhilong Xiu , Yi Tong

Bioresources and Bioprocessing ›› 2021, Vol. 8 ›› Issue (1) : 123

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Bioresources and Bioprocessing ›› 2021, Vol. 8 ›› Issue (1) : 123 DOI: 10.1186/s40643-021-00481-4
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Ionic liquid-based multi-stage sugaring-out extraction of lactic acid from simulated broth and actual lignocellulosic fermentation broth

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Abstract

IL-based sugaring-out extraction was applied to separate LA from fermentation broth

Different ILs and saccharides consisting systems were examined

The ability to form ATPS is in the order of [Hmim]BF4 ≈ [Bmim]BF4˃[Emim]BF4

The partition behaviors of LA, [Bmim]BF4, and saccharides were evaluated

LA recovery of 89.8% was obtained with removal of 68.4% cells and 65.4% pigments

Keywords

Ionic liquid / Sugaring-out extraction / Lactic acid / Multi-stage / Fermentation broth

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Xu Zhou, Yaqin Sun, Hongjun Zhan, Haijun Liu, Xiaoyan Wang, Yang Xu, Yi Li, Zhilong Xiu, Yi Tong. Ionic liquid-based multi-stage sugaring-out extraction of lactic acid from simulated broth and actual lignocellulosic fermentation broth. Bioresources and Bioprocessing, 2021, 8(1): 123 DOI:10.1186/s40643-021-00481-4

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Funding

National Natural Science Foundation of China(22078043)

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