Agro-industrial wastes and their utilization using solid state fermentation: a review

Abstract

Agricultural residues are rich in bioactive compounds. These residues can be used as an alternate source for the production of different products like biogas, biofuel, mushroom, and tempeh as the raw material in various researches and industries. The use of agro-industrial wastes as raw materials can help to reduce the production cost and also reduce the pollution load from the environment. Agro-industrial wastes are used for manufacturing of biofuels, enzymes, vitamins, antioxidants, animal feed, antibiotics, and other chemicals through solid state fermentation (SSF). A variety of microorganisms are used for the production of these valuable products through SSF processes. Therefore, SSF and their effect on the formation of value-added products are reviewed and discussed.

Keywords

Agro-industrial wastes / Oil cakes / Solid state fermentation / Bioactive compounds / Biotechnological approaches

References

[1] Adámez JD, Samino EG, Sánchez EV, González GD. In vitro estimation of the antibacterial activity and antioxidant capacity of aqueous extracts from grape-seeds (Vitis vinifera L.). Food Control, 2012, 24: 136-141.

[2] Akinyele JB, Fakoya S, Adetuyi CF. Anti-growth factors associated with Pleurotus ostreatus in a submerged liquid fermentation. Malays J Microbiol, 2012, 8: 135-140.

[3] Akpan I, Bankole MO, Adesemowo AM, Latunde DG. Production of amylase by A. niger in a cheap solid medium using rice bran and agricultural materials. Trop Sci, 1999, 39: 77-79.

[4] Asagbra AE, Sani AI, Oyewole OB. Solid state fermentation production of tetracycline by Streptomyces strains using some agricultural wastes as substrate. World J Microbiol Biotechnol, 2005, 21: 107-114.

[5] Avci A, Saha BC, Dien BS, Kennedy GJ, Cotta MA. Response surface optimization of corn stover pretreatment using dilute phosphoric acid for enzymatic hydrolysis and ethanol production. Biores Technol, 2013, 130: 603-612.

[6] Babu PD, Subhasree RS. Valuing the suitable agro-industrial wastes for cultivation of P. platypus and P. eous. Adv Biol Res, 2010, 4: 207-210.

[7] Belewu MA, Babalola FT. Nutrient enrichment of some waste agricultural residues after solid state fermentation using Rhizopus oligosporus. J Appl Biosci, 2009, 13: 695-699.

[8] Beuchat LR. Reddy NR, Pierson MD, Salunkhe DK. Oncom (fermented peanut presscake). Legume-based fermented foods, 1986, Boca Raton: CRC Press, 135-144.

[9] Bhargav S, Panda BP, Ali M, Javed S. Solid-state fermentation: an overview. Chem Biochem Eng, 2008, 22(1): 49-70.

[10] Bjerre AB, Olesen AB, Fernqvist T. Pretreatment of wheat straw using combined wet oxidation and alkaline hydrolysis resulting in convertible cellulose and hemicellulose. Biotechnol Bioeng, 1996, 49: 568-577.

[11] Bos A, Hamelinck C (2014) Greenhouse gas impact of marginal fossil fuel use. Project number: BIENL14773 2014

[12] Brendon RM (1957) Uganda Protectorate. Department of Veterinary Services and Animal Industry. Occasional Bulletin No. 1

[13] Buenrostro J, Ascacio A, Sepulveda L, De la Cruz R, Prado-Barragan A, Aguilar-Gonzalez MA, Rodriguez R, Aguilar CN. Potential use of different agro-industrial by products as supports for fungal ellagitannase production under solid state fermentation. Food Bioprod Process, 2013

[14] Cadoche L, Lopez GD. Assessment of size reduction as a preliminary step in the production of ethanol from lignocellulosic wastes. Biol Waste, 1989, 30: 153-157.

[15] Chang ST. The World Mushroom Industry: trends and technological development. Intern J Med Mushrooms, 2006, 8: 297-314.

[16] Chawla P, Bhandari L, Sadh PK, Kaushik R. Impact of solid state fermentation (Aspergillus oryzae) on functional properties and mineral bioavailability of black eyed pea (Vigna unguiculata) seed flour. Cereal Chem, 2017, 94(3): 437-442.

[17] Chiu SW, Moore D (2001) Threats to biodiversity caused by the traditional mushroom cultivation in China. In: Moore D, Nauta M, Rotheroe M (eds). Fungal conservation. The 21st Century issue Cambridge, pp 111–119

[18] Dharmendra KP. Production of lipase utilizing linseed oilcake as fermentation substrate. Intern J Sci Environ Technol, 2012, 1: 135-143.

[19] Duda-Chodak A, Tarko T. Antioxidant properties of different fruit seeds and peels. Acta Sci Pol Technol Aliment, 2007, 6: 29-36.

[20] Duhan JS, Bhardwaj M, Surekha. Free radical-scavenging and antimutagenic potential of acetone, chloroform and methanol extracts of leaves of Argemone maxicana. Intern J Pharma Biosci, 2011, 2(1): B455-B464.

[21] Duhan JS, Bhardwaj M, Surekha. Free radical-scavenging and antimutagenic potential of acetone, chloroform and methanol extracts of fruit of Argemone maxicana. Afr J Biotechnol, 2011, 10: 8654-8661.

[22] Duhan JS, Kumar A, Tanwar SK. Bioethanol production from starchy part of tuberous plant (potato) using Saccharomyces cerevisiae MTCC-170. Afr J Microbiol Res, 2013, 7: 5253-5260.

[23] Duhan JS, Mehta K, Sadh PK, Saharan P, Surekha. Bio-enrichment of phenolics and free radicals scavenging activity of wheat (WH-711) fractions by solid state fermentation with Aspergillus oryzae. Afr J Biochem Res, 2015, 10: 12-19.

[24] Duhan JS, Rana A, Sadh PK, Saharan P, Surekha. Antimicrobial and free radical scavenging activity of selective medicinal plants combination. World J Pharm Pharm Sci, 2015, 4: 1202-1216.

[25] Duhan JS, Bhardwaj M, Sadh PK, Surekha. In vitro antimicrobial efficacy, free radical scavenging activity and antimutagenic potential of stem extract of Capparis decidua. World J Pharma Pharm Sci, 2016, 5(10): 786-803.

[26] Ellaiah K, Adinarayana Y, Bhavani P, Padmaja B, Srinivasulu. Optimization of process parameters for glucoamylase production under solid-state fermentation by a new isolated Aspergillus species. Process Biochem, 2002, 38: 615-620.

[27] El-Tayeb TS, Abdelhafez AA, Ali SH, Ramadan EM. Effect of acid hydrolysis and fungal biotreatment on agro-industrial wastes for obtainment of free sugars for bioethanol production. Braz J Microbiol, 2012, 43(4): 1523-1535.

[28] Ewing WN. The feeds directory, 1997, Leicestershire England: Context Publications.

[29] Ezejiofor TIN, Duru CI, Asagbra AE, Ezejiofor AN, Orisakwe OE, Afonne JO, Obi E. Waste to wealth: production of oxytetracycline using streptomyces species from household kitchen wastes of agricultural produce. Afr J Biotechnol, 2012, 11: 10115-10124.

[30] Faisal PA, Hareesh ES, Priji P, Unni KN, Sajith S, Sreedevi S, Josh MS, Benjamin S. Optimization of parameters for the production of lipase from Pseudomonas sp. BUP6 by solid state fermentation. Adv Enzyme Res, 2014, 2: 125-133.

[31] Friesecke HK (1970) Final report. UNDP/SF Project No. 150 (IRQ/6)

[32] Gayen S, Ghosh U. Pectin methyl esterase production from mixed agro-wastes by Penicillium notatum NCIM 923 in solid state fermentation. J Bioremed Biodegrad, 2011, 2: 119.

[33] Gohl BI (1970) Animal feed from local products and by-products in the British Caribbean. Rome, FAO. AGA/Misc/70/25

[34] Graminha EBN, Goncalves AZL, Pirota RDPB, Balsalobre MAA, Silva R, Gomes E. Enzyme production by solid-state fermentation: application to animal nutrition. Anim Feed Sci Technol, 2008, 144: 1-22.

[35] Hegazy AE, Ibrahium MI. Antioxidant activities of orange peel extracts. World Appl Sci J, 2012, 18: 684-688.

[36] Ifudu ND (1986) Indigenous resources for antibiotic production, Nov/Dec. edn, Expansion Today Nigeria. African University Press Ltd, pp 52–53

[37] Ingale S, Joshi SJ, Gupte A. Production of bioethanol using agricultural waste: banana pseudo stem. Braz J Microbiol, 2014, 45(3): 885-892.

[38] Jacobs DR, Meyer KA, Kushi LH, Folsom AR. Is whole grain intake associated with reduced total and cause-specific death rates in older women? The Iowa women’s health study. Am J Pub Health, 1999, 89: 322-329.

[39] Jonathan SG, Babalola B (2013) Utilization of agro-industrial wastes for the cultivation of Pleurotus tuber-regium (Fries) Singer. Nigerian edible mushroom

[40] Jonathan SG, Fasidi IO, Ajayi AO, Adegeye A. Biodegradation of Nigerian wood wastes by Pleurotus tuber-regium (Fries) Singer. Bioresour Technol, 2008, 99: 807-811.

[41] Kalogeris E, Christakopoulos P, Katapodis P, Alexiou A, Vlachou S, Kekos D, Macris BJ. Production and characterization of cellulolytic enzymes from the thermophilic fungus Thermoascus aurantiacus under solid state cultivation of agricultural wastes. Process Biochem, 2003, 38: 1099-1104.

[42] Katalinic V, Mozina SS, Skroza D, Generalic I, Abramovic H, Milos M, Ljubenkov I, Piskernik S, Pezo I, Terpinc P, Boban M. Polyphenolic profile, antioxidant properties and antimicrobial activity of grape skin extracts of 14 Vitis vinifera varieties grown in dalmatia (Croatia). Food Chem, 2010, 119: 715-723.

[43] Kaur PS, Kaur S, Kaur H, Sharma A, Raj P, Panwar S. Solid substrate fermentation using agro industrial waste: new approach for amylase production by Bacillus licheniformis. Intern J Curr Microbiol Appl Sci, 2015, 4: 712-717.

[44] Kumar A, Duhan JS. Production and characterization of amylase enzyme isolated from Aspergillus niger MTCC-104 employing solid state fermentation. Intern J Pharam Biol Sci, 2011, 2: B250-B258.

[45] Kumar A, Duhan JS, Tanwar SK (2013a) Screening of Aspergillus spp. for extra cellular α-amylase activity. In: Khanna AK, Chopra G, Matta V, Singh, Bhutiani R (eds) Impact of global climate change on earth ecosystem. Biotech Books, New Delhi 205-214

[46] Kumar A, Duhan JS, Tanwar SK. Khanna AK, Chopra G, Matta V, Matta V, Singh, Bhutiani R. Screening of Aspergillus spp. for extra cellular α-amylase activity. Impact of global climate change on earth ecosystem, 2013, New Delhi: Biotech Books, 205-214.

[47] Kumar A, Duhan JS, Gahlawat SK, Surekha. Production of ethanol from tuberous plant (sweet potato) using Saccharomyces cerevisiae MTCC-170. Afr J Biotechnol, 2014, 13(28): 2874-2883.

[48] Kumar A, Sadh PK, Surekha, Duhan JS. Bio-ethanol production from sweet potato using co-culture of saccharolytic molds (Aspergillus spp.) and Saccharomyces cerevisiae MTCC170. J Adv Biotechnol, 2016, 6(1): 822-827.

[49] Kumhomkul T, Panich T. Lead accumulation in the straw mushroom, Volvariella volvacea, from lead contaminated rice straw and stubble. Bull Environ Contam Toxicol, 2013, 91: 231-234.

[50] Kuo LH. Animal feeding stu Vs compositional data of feeds and concentrates (part 3). Malays Agric J, 1967, 46: 63-70.

[51] Lakshmi S, Sornaraj R. Utilization of see food processing waste for cultivation of the edible mushroom Pleurotus flabellatus. Afr J Biotechnol, 2014, 17: 1779-1785.

[52] Lim G. Indigenous fermented foods in south east asia. ASEAN Food J, 1991, 6(3): 83-101.

[53] Limayema A, Ricke SC. Lignocellulosic biomass for bioethanol production: current perspectives, potential issues and future prospects. Prog Energy Combust Sci, 2012, 38: 449-467.

[54] Lina F, Ballesteros JA, Teixeira SI, Mussatto. Chemical, functional, and structural properties of spent coffee grounds and coffee silverskin. Food Bioprocess Technol, 2014, 7: 3493-3503.

[55] Mahalakshmi N, Jayalakshmi S. Amylase, cellulase and xylanase production from a novel bacterial isolate Achromobacter xylosoxidans isolated from marine environment. Intern J Adv Res Biol Sci, 2016, 3: 230-233.

[56] Maiti S, Sarma SJ, Brar SK, Le Bihan Y, Drogui P, Buelna G, Verma M. Agro-industrial wastes as feed stock for sustainable bio-production of butanol by Clostridium beijerinckii. Food Bioprod Process, 2016

[57] Mak ML (1986) Tempeh production from soybean milk wastes and soybeans by various Rhizopus strains. B.Sc. Hons thesis, Singapore National University Singapore

[58] Martin JGP, Porto E, Correa CB, Alencar SM, Gloria EM, Cabral ISR, Aquino LM. Antimicrobial potential and chemical composition of agro-industrial wastes. J Nat Prod, 2012, 5: 27-36.

[59] Maymone B, Battaglini A, Tiberio M. Ricerche sul valore nutritive della sansa d’olive. Alimentazione Animale Alimentazione Animale, 1961, 5: 219-250.

[60] Mehta K, Duhan JS. Production of invertase from Aspergillus niger using fruit peel waste as a substrate. Intern J Pharm Biol Sci, 2014, 5(2): B353-B360.

[61] Mondal AK, Sengupta S, Bhowal J, Bhattacharya DK. Utilization of fruit wastes in producing single cell protein. Intern J Sci Environ Technol, 2012, 1(5): 430-438.

[62] Motte JC, Trably E, Escudié R, Hamelin J, Steyer JP, Bernet N, Delgenes JP, Dumas C. Total solids content: a key parameter of metabolic pathways in dry anaerobic digestion. Biotechnol Biofuels, 2013, 6: 164.

[63] Murthy PS, Manonmani HK. Bioconversion of coffee industry wastes with white rot fungus Pleurotus florida. Res J Environ Sci, 2008, 2: 145-150.

[64] Mushimiyimana I, Tallapragada P. Bioethanol production from agro wastes by acid hydrolysis and fermentation process. J Sci Ind Res, 2016, 75: 383-388.

[65] Najafi G, Ghobadian B, Tavakoli T, Yusaf T. Potential of bioethanol production from agricultural wastes in Iran. Renew Sustain Energy Rev, 2009, 13: 1418-1427.

[66] Nascimento TP, Sales AE, Camila CS, Romero RMP, Takaki GMC, Teixeira JAC, Porto TS, Porto ALF. Production and characterization of new fibrinolytic protease from Mucor subtillissimus UCP 1262 in solid-state fermentation. Adv Enzyme Res, 2015, 3: 81-91.

[67] Negi S, Banerjee R. Optimization of extraction and purification of glucoamylase produced by A. awamori in solid state fermentation. Biotechnol Bioprocess Eng, 2009, 14: 60-66.

[68] Nguyen TAD, Kim KR, Han SJ, Cho HY, Kim JW, Park SM, Sim SJ. Pretreatment of rice straw with ammonia and ionic liquid for lignocelluloses conversion to fermentable sugars. Bioresour Technol, 2010, 101: 7432-7438.

[69] Nigam P, Singh D. Enzymes and microbial enzymes involved in starch processing enzymes. Enzyme Microbial Technol, 1995, 17: 770-778.

[70] Nigam PS, Gupta N, Anthwal A. Nigam PS, Pandey A. Pre-treatment of agro-industrial residues. Biotechnology for agro-industrial residues utilization, 2009, Heidelberg: Springer, 13-33.

[71] Okonko IO, Adeola OT, Aloysius FE, Damilola AO, Adewale OA. Utilization of food wastes for sustainable development. Electr J Environ Agric Food Chem, 2009, 8(4): 263-286.

[72] Oliveira F, Carlos ES, Peclat Veronica ROL, Salgado JM, Bernardo DR, Maria AZC, Armando V, Isabel B. Optimization of lipase production by Aspergillus ibericus from oil cakes and its application in esterification reactions. Food Bioprod Process, 2017

[73] Orzuaa MC, Mussattob SI, Contreras EJC, Rodrigueza R, Garzaa HTA, Aguilara CN. Exploitation of agro-industrial wastes as immobilization carrier for solid-state fermentation. Ind Crops Prod, 2009, 30: 24-27.

[74] Owusu K, Christensen DA, Owen BD. Nutritive value of some Ghanian feed-stu Vs. Can J Anim Sci, 1970, 50: 1-14.

[75] Paepatung N, Nopharatana A, Songkasiri W. Bio-methane potential of biological solid materials and agricultural wastes. Asian J Energy Env, 2009, 10: 19-27.

[76] Pandey A. Solid state fermentation. Biochem Eng J, 2003, 13: 81-84.

[77] Pandey A, Soccol CR, Mitchell D. New developments in solid state fermentation: I-bioprocesses and products. Process Biochem, 2000, 35: 1153-1169.

[78] Parashar S, Sharma H, Garg M. Antimicrobial and antioxidant activities of fruits and vegetable peels: a review. J Pharmcogn Phytochem, 2014, 3: 160-164.

[79] Rahman KHA, Yusof SJHM, Zakaria Z. Bioproteins production from palm oil agro-industrial wastes by Aspergillus terreus UniMAP AA-1 Pertanika. J Trop Agric Sci, 2016, 39: 29-39.

[80] Ramachandran S, Patel AK, Nampoothiri KM, Francis F, Nagy V, Szakacs G, Pandey A. Coconut oil cake—a potential raw material for the production of a-amylase. Bioresour Technol, 2004, 93: 169-174.

[81] Ramachandran S, Singh SK, Larroche C, Soccol CR, Pandey A. A oil cakes and their biotechnological applications—a review. Bioresour Technol, 2007, 98: 2000-2009.

[82] Rana A, Saharan P, Sadh PK, Surekha, Duhan JS. Free radical scavenging and antimicrobial potential of mixture of selective medicinal plants. Asian J Pharm Clinical Res, 2014, 7: 27-32.

[83] Randive SD. Cultivation and study of growth of oyster mushroom on different agricultural waste substrate and its nutrient analysis. Adv Appl Sci Res, 2012, 3: 1938-1949.

[84] Rashad MM, Mahmoud AE, Ali MM, Nooman MU, Al-Kashef AS. Antioxidant and anticancer agents produced from pineapple waste by solid state fermentation. Intern J Toxicol Pharmacol Res, 2015, 7(6): 287-296.

[85] Rekha KSS, Lakshmi C, Devi SV, Kumar MS. Production and optimization of lipase from Candida rugosa using groundnut oilcake under solid state fermentation. Intern J Res Eng Technol, 2012, 1: 571-577.

[86] Rivas B, Torrado A, Torre P, Converti A, Domínguez JM. Submerged citric acid fermentation on orange peel autohydrolysate. J Agric Food Chem, 2008, 56: 2380-2387.

[87] Rodríguez-Couto S. Exploitation of biological wastes for the production of value-added products under solid-state fermentation conditions. Biotechnol J, 2008, 3: 859-870.

[88] Rudra SG, Nishad J, Jakhar N, Kaur C. Food industry waste: mine of nutraceuticals. Intern J Sci Environ Technol, 2015, 4(1): 205-229.

[89] Sadh PK, Chawla P, Bhandari L, Kaushik R, Duhan JS. In vitro assessment of bio-augmented minerals from peanut oil cakes fermented by Aspergillus oryzae through Caco-2 cells. J Food Sci Techol, 2017, 54: 3640-3649.

[90] Sadh PK, Duhan JS, Surekha, Saharan P. Bio-augmentation of phenolics and antioxidant activity of Oryza sativa by solid state fermentation with Aspergillus spp. Intern Food Res J, 2017, 24(3): 1160-1166.

[91] Sadh PK, Saharan P, Duhan JS. Bio-augmentation of antioxidants and phenolic content of Lablab purpureus by solid state fermentation with GRAS filamentous fungi. Resour Effic Technol, 2017, 3: 285-292.

[92] Sadh PK, Saharan P, Duhan S, Duhan JS. Bio-enrichment of phenolics and antioxidant activity of combination of Oryza sativa and Lablab purpureus fermented with GRAS filamentous fungi. Resour Effic Technol, 2017, 3: 347-352.

[93] Sadh PK, Chawla P, Bhandari L, Duhan JS. Bio-enrichment of functional properties of peanut oil cakes by solid state fermentation using Aspergillus oryzae. J Food Meas Character, 2017

[94] Saharan P, Duhan JS (2013) Studies on antioxidant activity, total phenolic and flavanoid contents of leaf extracts of Thuja orientalis. In: Khanna DR, Chopra AK, Matta G, Singh V, Bhutiani R (eds) Impact of global climate change on earth ecosystem. Biotech Books, New Delhi, pp 193–203. ISBN 978-81-7622-271-6

[95] Saharan P, Duhan JS, Gahlawat SK, Surekha. Antioxidant potential of various extracts of stem of Thuja orientalis: in vitro study. Intern J Appl Biol Pharm Technol, 2012, 3: 264-271.

[96] Saharan P, Sadh PK, Duhan JS. Comparative assessment of effect of fermentation on phenolics, flavonoids and free radical scavenging activity of commonly used cereals. Biocatal Agric Biotechnol, 2017, 12: 236-240.

[97] Saini JK, Saini R, Tewari L. Lignocellulosic agriculture wastes as biomass feedstocks for second-generation bioethanol production: concepts and recent developments. 3. Biotech, 2014

[98] Saravanan V, Vijayakumar S. Production of biosurfactant by Pseudomonas aeruginosa PB3A using agro-industrial wastes as a carbon source. Malays J Microbiol, 2014, 10(1): 57-62.

[99] Sharanappa A, Wani KS, Pallavi P. Bioprocessing of food industrial waste for α-amylase production by solid state fermentation. Intern J Adv Biotechnol Res, 2011, 2: 473-480.

[100] Sindiri MK, Machavarapu M, Vangalapati M. Alfa-amylase production and purification using fermented orange peel in solid state fermentation by Aspergillus niger. Ind J Appl Res, 2013, 3: 49-51.

[101] Singh S, Genitha I. Extraction of antioxidants from fruit peels and its utilization in paneer. J Food Process Technol, 2014, 5: 7.

[102] Singhania RR, Patel AK, Soccol CR, Pandey A. Recent advances in solid-state fermentation. Biochem Engin J, 2009, 44: 13-18.

[103] Siqueira F, Martos E, Silva R, Dias E. Cultivation of Pleurotus sajor-caju on banana stalk and Bahia grass based substrates. Hortic Bras, 2011, 29: 199-204.

[104] Sodhi HK, Sharma K, Gupta JK, Soni SK. Production of a thermostable a-amylase from Bacillus sp. PS-7 by solid-state fermentation and its synergistic use in the hydrolysis of malt starch for alcohol production. Process Biochem, 2005, 40: 525-534.

[105] Steinkraus KH. Handbook of indigenous fermented foods, 1983, New York: M Dekker Inc.

[106] Suganthi R, Benazir JF, Santhi R, Kumar RV, Hari A, Meenakshi N, Nidhiya KA, Kavitha G, Lakshmi R. Amylase production by Aspergillus niger under solid state fermentation using agro-industrial wastes. Intern J Eng Sci Technol, 2011, 3: 1756-1763.

[107] Sukan A, Roy I, Keshavarz T. Agro-industrial waste materials as substrates for the production of poly (3-hydroxybutyric acid). J Biomater Nanobiotechnol, 2014, 5: 229-240.

[108] Thakur SA, Nemade SN, Sharanappa A. Solid state fermentation of overheated soybean meal (waste) for production of protease using Aspergillus oryzae. Inten J Innov Res Sci Eng Technol, 2015, 4: 18456-18461.

[109] Thomas L, Larroche C, Pandey A. Current developments in solid-state fermentation. Biochem Eng J, 2013, 81: 146-161.

[110] Topakas E, Kalogeris E, Kekos D, Macris BJ, Christakopoulos P. Production of phenolics from corn cabs by coupling enzymic treatment and solid state fermentation. Eng Life Sci, 2004, 4(3): 283-286.

[111] Tripathi KD. Antimicrobial drugs. Essentials of medical pharmacology, 2008, 6, New Delhi: Jaycee Brothers Medical Publishers Ltd, 710.

[112] Van Veen AG, Graham DCW, Steinkraus KH. Fermented peanut press cake. Cereal Sci Today, 1968, 13: 96-99.

[113] Vastrad BM, Neelagund SE. Optimization and production of neomycin from different agro industrial wastes in solid state fermentation. Intern J Pharma Sci Drug Res, 2011, 3: 104-111.

[114] Vastrad BM, Neelagund SE. Optimization of process parameters for rifamycin b production under solid state fermentation from Amycolatopsis mediterranean MTCC 14. Intern J Curr Pharm Res, 2011, 4: 101-108.

[115] Vidhyalakshmi R, Vallinachiyar C, Radhika R. Production of xanthan from agro-industrial waste. J Adv Sci Res, 2012, 3: 56-59.

[116] Wang L, Yang ST. Solid state fermentation and its applications. In bioprocessing for value-added products from renewable resources: new technologies and applications, 2007, Amsterdam: Elsevier, 465-489.

[117] Weshahy AA, Rao VA (2012) Potato peel as a source of important phytochemical antioxidant nutraceuticals and their role in human health—a review. Phytochemicals as nutraceuticals—Global approaches to their role in nutrition and health pp 207–224

[118] Win MM, Azizah AH, Bablishah BS, Farooq A, Mandumpal SC, Mohd PS. Phenolic compounds and antioxidant activity of peanut’s skin, hull, raw kernel and roasted kernel flour. Pak J Bot, 2011, 43: 1635-1642.

[119] Yang SS, Swei WJ. Cultural condition and oxytetracycline production by Streptomyces rimosus in solid state fermentation of corn cob. World J Microbiol Biotechnol, 1996, 12: 43-46.

[120] Zafar S (2014) Waste management, waste-to-energy.​ https://www.bioenergyconsult.com/tag/waste-to-energy