The continuous growth of global agribusiness stimulates the search for alternatives that can enhance the performance and quality of life of production animals. In swine production systems, multiple challenges arise during the post-weaning phase when piglets face substantial transitions, including diet changes, environmental shifts, and maternal separation. These stressors often lead to reduced feed intake and inadequate nutrient consumption, resulting in impaired growth and increased susceptibility to diseases, even mortality in extreme cases. To counter these challenges, the use of palatability enhancers has emerged as an essential strategy to stimulate feed consumption, ensuring sufficient nutrient intake and promoting the health and welfare of piglets. Considering the crucial role of taste perception and dietary preferences in pigs, this review explores the mechanisms behind taste perception, the impact of various palatability additives on feed intake, and highlights current advances in strategies designed to optimize the feeding of newly weaned piglets.
| [1] |
H. H. Stein and G. C. Shurson, “Board-Invited Review: The Use and Application of Distillers Dried Grains With Solubles in Swine Diets,” Journal of Animal Science 87, no. 4 (2009): 1292–1303, https://doi.org/10.2527/jas.2008-1290.
|
| [2] |
B. C. Zhao, T. H. Wang, J. Chen, B. H. Qiu, Y. R. Xu, and J. L. Li, “Essential Oils Improve Nursery Pigs' Performance and Appetite via Modulation of Intestinal Health and Microbiota,” Animal Nutrition 16 (2024): 174–188, https://doi.org/10.1016/j.aninu.2023.10.007.
|
| [3] |
L. Blavi, D. Solà-Oriol, P. Llonch, S. López-Vergé, S. M. Martín-Orúe, and J. F. Pérez, “Management and Feeding Strategies in Early Life to Improve Performance and Welfare of Piglets Around Weaning: A Review,” Animals 11, no. 2 (2021): 302, https://doi.org/10.3390/ani11020302.
|
| [4] |
Brazilian Association of Animal Protein (ABPA), Annual Report 2024 (São Paulo: ABPA, 2024), http://abpa-br.org/wp-content/uploads/2024/04/ABPA-Relatorio-Anual-2024_capa_frango.pdf.
|
| [5] |
K. McCrickerd and C. G. Forde, “Sensory Influences on Food Intake Control: Moving Beyond Palatability,” Obesity Reviews 17, no. 1 (2016): 18–29, https://doi.org/10.1111/obr.12340.
|
| [6] |
J. R. Pluske, D. L. Turpin, and J. C. Kim, “Gastrointestinal Tract (Gut) Health in the Young Pig,” Animal Nutrition 4, no. 2 (2018): 187–196, https://doi.org/10.1016/j.aninu.2017.12.004.
|
| [7] |
P. H. Hemsworth and G. J. Coleman, Human-Livestock Interactions: The Stockperson and the Productivity and Welfare of Intensively Farmed Animals, 2nd ed. (CABI, 2011).
|
| [8] |
S. A. Guzmán-Pino, C. Lazcano, V. De Luca, J. Figueroa, C. Valenzuela, and E. Roura, “Inclusion of Monosodium Glutamate in the Diet of Gestating and Lactating Sows Modifies Preference Thresholds and Sensory-Motivated Intake for Umami and Sweet Solutions in Post-Weaning Piglets,” Animals 9, no. 6 (2019): 336, https://doi.org/10.3390/ani9060336.
|
| [9] |
C. Clouard and D. Val-Laillet, “Impact of Sensory Feed Additives on Feed Intake, Feed Preferences, and Growth of Female Piglets During the Early Post-Weaning Period,” Journal of Animal Science 92, no. 5 (2014): 2133–2140, https://doi.org/10.2527/jas.2013-6809.
|
| [10] |
E. Roura, “Recent Studies on the Biology of Taste and Olfaction in Mammals,” in New Approaches in Pig Nutrition (Feed Additives Division, 2003), 14: Lucta SA.
|
| [11] |
G. K. Beauchamp, P. Jiang, and M. Nonaka, “Comparative Biology of Taste: Insights Into Mechanism and Function,” Flavour 4, no. 1 (2015): 1–3, https://doi.org/10.1186/2044-7248-4-1.
|
| [12] |
W. Wang, X. Zhou, and Y. Liu, “Characterization and Evaluation of Umami Taste: A Review,” Trends in Analytical Chemistry 127 (2020): 115876, https://doi.org/10.1016/j.trac.2020.115876.
|
| [13] |
H. D. B. Maluly, The Perception of Basic Tastes (Umami Portal – Scientific Studies, 2021).
|
| [14] |
Y. Toda, T. Nakagita, T. Hirokawa, et al., “Positive/Negative Allosteric Modulation Switching in an Umami Taste Receptor (T1R1/T1R3) by a Natural Flavor Compound, Methional,” Scientific Reports 8, no. 1 (2018): 11796, https://doi.org/10.1038/s41598-018-30315-x.
|
| [15] |
J. Figueroa, D. Frías, D. Solà-Oriol, et al., “Palatability in Pigs: The Pleasure of Consumption,” Journal of Animal Science 97, no. 5 (2019): 2165–2174, https://doi.org/10.1093/jas/skz085.
|
| [16] |
K. Ninomiya, “Umami: A Universal Taste,” Food Reviews International 18, no. 1 (2002): 23–38, https://doi.org/10.1081/fri-120003415.
|
| [17] |
J. M. Campbell, J. D. Crenshaw, and J. Polo, “The Biological Stress of Early-Weaned Piglets,” Journal of Animal Science and Biotechnology 4, no. 1 (2013): 19, https://doi.org/10.1186/2049-1891-4-19.
|
| [18] |
G. A. Santos, A. S. Silva, V. Ribeiro Junior, et al., “Impact of the Type of Weaning on Piglets: A Literature Review,” Brazilian Journal of Development 7, no. 9 (2021): 92351–92366, https://doi.org/10.34117/bjdv7n9-413.
|
| [19] |
A. J. Moeser, K. A. Ryan, P. K. Nighot, and A. T. Blikslager, “Gastrointestinal Dysfunction Induced by Early Weaning Is Attenuated by Delayed Weaning and Mast Cell Blockade in Pigs,” American Journal of Physiology—Gastrointestinal and Liver Physiology 293, no. 2 (2007): G413–G421, https://doi.org/10.1152/ajpgi.00304.2006.
|
| [20] |
D. Glaser, M. Wanner, J. M. Tinti, and C. Nofre, “Pig Responses to Taste Stimuli,” in Chemical Signals in Vertebrates, Vol. 9 (Springer, 2001), 423–431, https://doi.org/10.1007/978-1-4615-0671-3_58.
|
| [21] |
Q. Tang, T. Lan, C. Zhou, et al., “Nutrition Strategies to Control Post-Weaning Diarrhea of Piglets: From the Perspective of Feeds,” Animal Nutrition 17 (2024): 297–311, https://doi.org/10.1016/j.aninu.2024.03.006.
|
| [22] |
E. M. A. M. Bruininx, C. M. van der Peet-Schwering, J. W. Schrama, et al., “Individually Measured Feed Intake Characteristics and Growth Performance of Group-Housed Weanling Pigs: Effects of Sex, Initial Body Weight, and Body Weight Distribution Within Groups,” Journal of Animal Science 79, no. 2 (2001): 301–308, https://doi.org/10.2527/2001.792301x.
|
| [23] |
M. P. Walter, N. Biondo, P. E. Bennemann, D. Dallanora, and B. T. Marimon, “Factors Predisposing to the Occurrence of Diseases in Nursery Pigs,” in Swine and Poultry Production: From Basics to Precision Zootechnics (Editora Científica Digital, 2021), 193–202: Chapter 13.
|
| [24] |
C. L. Carvalho, M. M. Cavalcante, N. O. T. Camargo, and I. Andretta, “Animal Welfare in Swine,” in Swine and Poultry Production: From Basics to Precision Zootechnics (Editora Científica Digital, 2021), 90–115.
|
| [25] |
M. S. Dawkins, “Animal Welfare and Efficient Farming: Is Conflict Inevitable?,” Animal Production Science 57, no. 2 (2016): 201–208, https://doi.org/10.1071/AN15383.
|
| [26] |
L. Zheng, M. E. Duarte, A. Sevarolli Loftus, and S. W. Kim, “Intestinal Health of Pigs Upon Weaning: Challenges and Nutritional Intervention,” Frontiers in Veterinary Science 8 (2021): 628258, https://doi.org/10.3389/fvets.2021.628258.
|
| [27] |
L. Zhu, G. Wang, B. Dong, et al., “Effects of Sweetener Neotame on Diet Preference, Performance, and Hematological and Biochemical Parameters of Weaned Piglets,” Animal Feed Science and Technology 214 (2016): 86–94, https://doi.org/10.1016/j.anifeedsci.2016.02.01.
|
| [28] |
J. Borgo, L. C. Laurella, F. Martini, C. A. N. Catalán, and V. P. Sülsen, “Stevia Genus: Phytochemistry and Biological Activities Update,” Molecules 26, no. 9 (2021): 2733, https://doi.org/10.3390/molecules26092733.
|
| [29] |
M. R. Jansen and K. Kim, “Evaluating the Effects of Non-Nutritive Sweeteners on Pigs: A Systematic Review,” Animals 14, no. 20 (2024): 3032, https://doi.org/10.3390/ani14203032.
|
| [30] |
C. E. Riera, H. Vogel, S. A. Simon, and J. L. Coutre, “Artificial Sweeteners and Salts Producing a Metallic Taste Sensation Activate TRPV1 Receptors,” American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 293, no. 2 (2007): R626–R634, https://doi.org/10.1152/ajpregu.00286.2007.
|
| [31] |
F. E. L. Budiño, L. Lucchesi, and I. P. Otsuk, “Use of Sweetener as a Palatability Enhancer in the Diet of Weaned Piglets,” Boletim de Industria Animal 71, no. 1 (2014): 58–62, https://doi.org/10.17523/bia.v71n1p58.
|
| [32] |
S. A. Zhang and J. Xu, “Development Status and Forecast of the Pig Industry in China,” Advances in Economics, Management and Political Science 155 (2025): 21–26, https://doi.org/10.54254/2754-1169/2024.GA19627.
|
| [33] |
V. R. C. De Paula, M. L. P. Tse, P. V. A. Alvarenga, et al., “Sweeteners on Diet Preference of Weaned Piglets,” in Proceedings of the II International Symposium on Swine Production and Health (II Simpósio Internacional de Produção e Sanidade de Suínos) (UNESP, 2017).
|
| [34] |
B. Keimer, S. Kröger, I. Röhe, R. Pieper, A. Simon, and J. Zentek, “Effects of a Hydrolysed Yeast (Kluyveromyces fragilis) on Feed Intake and Zootechnical Performance in Weaned Piglets,” in Proceedings of the BOKU Symposium on Animal Nutrition (BOKU-symposium Tierernährung), (2016).
|
| [35] |
M. Duengelhoef, “Sensory Additives,” in Feed Intake and Food Preference of Domestic Animals, ed S. L. Vieira, Chapter 6, (2010), 290–314.
|
| [36] |
B. N. Paulino, A. Sales, L. Oliveira Felipe, G. M. Pastore, G. Molina, and J. L. Bicas, “Biotechnological Production of Non-Volatile Flavor Compounds,” Current Opinion in Food Science 41 (2021): 26–35, https://doi.org/10.1016/j.cofs.2021.02.002.
|
| [37] |
W. Boontiam, C. Bunchasak, Y. Y. Kim, S. Kitipongpysan, and J. Hong, “Hydrolyzed Yeast Supplementation to Newly Weaned Piglets: Growth Performance, Gut Health, and Microbial Fermentation,” Animals 12, no. 3 (2022): 350, https://doi.org/10.3390/ani12030350.
|
| [38] |
V. Sampath, K. Han, S. Sureshkumar, and I. H. Kim, “Impact of Yeast Hydrolysate (Saccharomyces cerevisiae) Supplementation on the Growth Performance, Nutrient Digestibility, Fecal Microflora, Noxious Gas Emission, Blood Profile, and Meat Quality of Finishing Pigs,” Canadian Journal of Animal Science 102, no. 1 (2021): 98–107, https://doi.org/10.1139/cjas-2021-0025.
|
| [39] |
J. L. Genova, I. F. Leal, P. E. Rupolo, L. E. dos Reis, and V. M. Barbosa, “Limiting Amino Acids in Swine Nutrition,” Nutritime Revista Eletrônica 14, no. 5 (2017): 7032–7045, ISSN: 1983–9006.
|
| [40] |
A. Vasilaki, E. Panagiotopoulou, T. Koupantsis, E. Katsanidis, and I. Mourtzinos, “Recent Insights into Flavor Enhancers: Definition, Mechanism of Action, Flavor-Enhancing Ingredients, Analytical Techniques, and Potential Uses,” Critical Reviews in Food Science and Nutrition 62, no. 32 (2021): 9036–9052, https://doi.org/10.1080/10408398.2021.1939264.
|
| [41] |
D. M. Hartl, O. Frank, V. S. Hänel, V. Heigl, C. Dawid, and T. F. Hofmann, “Isolation and Identification of Novel Taste-Modulating N2-Guanosine 5′-Monophosphate Derivatives Generated by Maillard-Type Reactions,” Journal of Agricultural and Food Chemistry 72, no. 25 (2024): 14284–14293, https://doi.org/10.1021/acs.jafc.4c03485.
|
| [42] |
Brazil. Ministry of Agriculture, Livestock and Supply, “Normative Instruction No. 110/2020: List of Raw Materials for Animal Feed,” Brasília: MAPA (2020): [Internet], http://www.gov.br/agricultura/pt-br/assuntos/insumos-agropecuarios/insumos-pecuarios/alimentacao-animal/arquivos-alimentacao-animal/copy2_of_IN1102020LISTADEMATERIASPRIMAS.pdf.
|
| [43] |
Brazil. Ministry of Agriculture, Livestock and Supply, “General List of Agricultural Inputs: Animal Feed,” Brasília: MAPA (2023): [Internet], https://www.gov.br/agricultura/pt-br/assuntos/insumos-agropecuarios/insumos-pecuarios/alimentacao-animal/listageral13032023.pdf.
|
| [44] |
C. S. Nunes, A. Kunamneni, V. Kumar, and H. M. Habte-Tsion, “Registration of Feed and Food Additives (Enzymes) in the United States, Canada, and China,” in Enzymes in Human and Animal Nutrition. 1st ed. (Elsevier, 2018), 457–480, https://doi.org/10.1016/b978-0-12-805419-2.00024-1.
|
| [45] |
European Union, “Council Directive 70/524/EEC Concerning Additives in Feeding-Stuffs,” Official Journal of the European Communities (November 1970).
|
| [46] |
J. Xu, “Development Status and Forecast of Pig Industry in China,” AEMPS (Advances in Economics, Management and Political Science) 155, no. 1 (2025): 21–26, https://doi.org/10.54254/2754-1169/2024.GA19627.
|
| [47] |
General Administration of Customs of China (GACC). (2021). Decree No. 249 on the Promulgation of the Measures for the Administration of Import and Export Food Safety of the People’s Republic of China, https://www.gov.br/agricultura/pt-br/assuntos/inspecao/produtos-vegetal/exportacao-dipov/DIPOV_4.2021.CHINA.5.1.1.71/decreto_n-_249_da_gacc-_pt-decreto-sobre-a-promulgacao-das-medidas-de-gestao-de-seguranca-dos-alimentos-importados-e-exportados-da-republica-popular-da-china.
|
| [48] |
United States Department of Agriculture (USDA), Standard for Food Additive Use – GB2760-2015, (2015), https://apps.fas.usda.gov/newgainapi/api/report/downloadreportbyfilename?filename=Standard%20for%20Food%20Additive%20Use%20-%20GB2760-2015_Beijing_China%20-%20Peoples%20Republic%20of_4-28-2015.pdf.
|
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