Human schistosomiasis: A living review of clinical and epidemiological concepts

Rodrigo Siqueira-Batista , Paulo Sérgio Balbino Miguel , Andréia Patrícia Gomes , Graziela Almeida Cupertino , Teresa Baptista-Fernandes , Ademir Nunes Ribeiro Júnior , Sávio Silva Santos

Asian Pacific Journal of Tropical Medicine ›› 2025, Vol. 18 ›› Issue (12) : 528 -540.

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Asian Pacific Journal of Tropical Medicine ›› 2025, Vol. 18 ›› Issue (12) :528 -540. DOI: 10.4103/apjtm.apjtm_323_25
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Human schistosomiasis: A living review of clinical and epidemiological concepts
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Abstract

Schistosomiasis, as a neglected tropical disease, presents a public health challenge, particularly in impoverished tropical and subtropical areas. This living review focuses on the key aspects of schistosomiasis, including its etiology, epidemiology, pathophysiology, clinical features, diagnosis, prophylaxis, treatment, and control. We also examine the key aspects of schistosomiasis caused by Schistosoma mekongi, Schistosoma bovis, and Schistosoma curassoni. To date, praziquantel is the main drug for treating and reducing the transmission of schistosomiasis. The development of vaccines remains an important scientific goal in the control of this neglected disease.

Keywords

Schistosomiasis / Katayama fever

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Rodrigo Siqueira-Batista, Paulo Sérgio Balbino Miguel, Andréia Patrícia Gomes, Graziela Almeida Cupertino, Teresa Baptista-Fernandes, Ademir Nunes Ribeiro Júnior, Sávio Silva Santos. Human schistosomiasis: A living review of clinical and epidemiological concepts. Asian Pacific Journal of Tropical Medicine, 2025, 18 (12) : 528-540 DOI:10.4103/apjtm.apjtm_323_25

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