Fluid-sparing hyperoncotic albumin in severe dengue: A retrospective case series

Quan Le , Hang Trinh , Nhan Vu

Asian Pacific Journal of Tropical Medicine ›› 2026, Vol. 19 ›› Issue (5) : 226 -230.

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Asian Pacific Journal of Tropical Medicine ›› 2026, Vol. 19 ›› Issue (5) :226 -230. DOI: 10.4103/apjtm.apjtm_142_26
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Fluid-sparing hyperoncotic albumin in severe dengue: A retrospective case series
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Quan Le, Hang Trinh, Nhan Vu. Fluid-sparing hyperoncotic albumin in severe dengue: A retrospective case series. Asian Pacific Journal of Tropical Medicine, 2026, 19 (5) : 226-230 DOI:10.4103/apjtm.apjtm_142_26

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Ethical approval and institutional review board approval

The study protocol was reviewed and approved by the Institutional Review Board (Ethics Committee) of Xuyen A General Hospital (Approval Number: 15/2026/QD-BVXA, dated February 2, 2026). The study was conducted in accordance with the Declaration of Helsinki.

Consent to participate

Patient consent was waived by the Institutional Review Board due to the retrospective, observational nature of this study. All patient data were fully anonymized and de-identified prior to analysis to ensure strict confidentiality.

Data availability statement

The datasets generated and analyzed during the current study are not publicly available to protect patient confidentiality but are available from the corresponding author on reasonable request.

Declaration of generative AI and AI-assisted technologies in the writing process

During the preparation of this work, the author used Google Gemini to translate parts of the initial draft from Vietnamese to English and to polish the academic language to meet publication standards. After using this tool/service, the author thoroughly reviewed and edited the content as needed and takes full responsibility for the accuracy, integrity, and originality of the final publication.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Author contributions’ statement

QL: Conceptualization, methodology, data curation, formal analysis, writing-original draft, writing-review & editing. HT: Data curation, validation, writing-review & editing. NV: Investigation, resources, validation.

Publisher’s note

The Publisher of the Journal remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Edited by Pan Y, Lei Y, Zhang Q

Acknowledgements

The authors would like to thank the medical and nursing staff at the Intensive Care Unit of Xuyen A General Hospital - Duc Hoa Branch for their dedicated patient care and support during data collection.

References

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Kaur A, Bhargava S, Dhooria GS, Pooni PA, Bhat D, Arora K, et al. Albumin infusion in children with fluid refractory severe dengue: A comparative study. Indian Pediatr 2025; 62(2): 102-108. doi: 10.1007/s13312-025-3372-8.

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Bur R, Suwarto S, Pohan HT, Prihartono J, Harahap AR, Dewi BE, et al. Early intervention of 5% albumin shown superior control of vascular integrity and function compared to ringer's lactatein hospitalized adult with grade I & II dengue hemorrhagic fever: A multicenter randomized controlled trial in Indonesia. Trop Dis Travel Med Vacc 2024; 10(1): 20. doi: 10.1186/s40794-024-00230-3.

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