5-Fluorouracil loaded nanogels attenuate hepatotoxicity by modulating PI3K/AKT, NF-κB, and METTL14 pathways

Gehan R. Abdel-Hamid , Ahmed Hammad , Hayam Mostafa , Dalia E. El-Nashar , Assmaa Fathi Abd Elkhalek , Eman S. Eldin , Monda M.M Badawy

Asian Pacific Journal of Tropical Biomedicine ›› 2026, Vol. 16 ›› Issue (7) : 306 -316.

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Asian Pacific Journal of Tropical Biomedicine ›› 2026, Vol. 16 ›› Issue (7) :306 -316. DOI: 10.4103/apjtb.apjtb_185_26
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5-Fluorouracil loaded nanogels attenuate hepatotoxicity by modulating PI3K/AKT, NF-κB, and METTL14 pathways
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5-Fluorouracil / Nanogel drug delivery / Hepatotoxicity / NF-κB signaling / PI3K/AKT/mTOR pathway / Network pharmacology

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Gehan R. Abdel-Hamid, Ahmed Hammad, Hayam Mostafa, Dalia E. El-Nashar, Assmaa Fathi Abd Elkhalek, Eman S. Eldin, Monda M.M Badawy. 5-Fluorouracil loaded nanogels attenuate hepatotoxicity by modulating PI3K/AKT, NF-κB, and METTL14 pathways. Asian Pacific Journal of Tropical Biomedicine, 2026, 16 (7) : 306-316 DOI:10.4103/apjtb.apjtb_185_26

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