Effects of SARS-CoV-2 infection on pregnancy outcome: An overview

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may have harmful effects on expectant moms, labor, and newborns born to infected mothers. There is a risk of the initiation of pregnancy with infection. Even if the gametes are non-infected, pregnancies could be exposed later for infection by coronavirus. Investigations of COVID-19 during pregnancy highlighted the non-transmission or surprising transmission of SARS-CoV-2 to the offspring. However, other studies have exhibited the potential mother-to-fetus transmission. In this way, unanswered concerns about SARS-CoV-2 fetal transmission and the particular interface(s) controlling its pathogenesis throughout pregnancy persist. This review focuses on the potential effects of SARS-CoV-2 on vertical transmission, as well as the influence of the virus on pregnancy and placenta.

Keywords

SARS-CoV-2 / Hazard effects / Pregnancy / Placenta

Conflict of interest statement

The author declares that he has no competing interests.

Funding

The study received no extramural funding.

Author's contributions

Yahia A. Amin conducted a literature search and wrote a rough draft. The study was conceptualized, planned, and conducted by Yahia A. Amin. He also created figures and edited and revised the article.

Publisher' s Note

The Publisher of the Journal remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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