The global analysis of the SEIR epidemic model with vaccination and population births
Zuoheng Chen , Youhui Su , Qian Wen , Feng-Lan Tu
Electronic Research Archive ›› 2025, Vol. 33 ›› Issue (12) : 7289 -7309.
This paper constructs a Susceptible-Exposed-Infectious-Recovered (SEIR) model that takes into account the dynamic changes in the birth population and includes both vaccinated and unvaccinated populations. The basic reproduction number R0 is derived, and its global stability is analyzed. It is proven that when R0 < 1, the disease-free equilibrium point is globally stable. When R0 > 1, there exist an unstable disease-free equilibrium and a unique endemic equilibrium. Subsequently, we conduct the numerical simulations to validate theoretical results and plot data visualizations for various scenarios. In addition, the parameter sensitivity analysis and the forward bifurcation of the model are performed to examine how each system parameter specifically affects disease transmission. Our results offer practical insights for public health planning, particularly in optimizing vaccination strategies in populations with high birth rates or waning immunity.
SEIR model / vaccination / bifurcation / global stability / basic reproduction number
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