Acupuncture for Crohn's disease: current status and future perspectives

Chunhui Bao , Jinrong Zhang , Huangan Wu

Acupuncture and Herbal Medicine ›› 2023, Vol. 3 ›› Issue (4) : 229 -231.

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Acupuncture and Herbal Medicine ›› 2023, Vol. 3 ›› Issue (4) : 229 -231. DOI: 10.1097/HM9.0000000000000081
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Acupuncture for Crohn's disease: current status and future perspectives

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Chunhui Bao, Jinrong Zhang, Huangan Wu. Acupuncture for Crohn's disease: current status and future perspectives. Acupuncture and Herbal Medicine, 2023, 3(4): 229-231 DOI:10.1097/HM9.0000000000000081

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Conflict of interest statement

The authors declare no conflict of interest.

Funding

This work was supported by the Natural Science Foundation of Shanghai (No. 22ZR1458300), Special Clinical Research Project in the Health Industry of Shanghai Municipal Health Commission (No. 202340036), and the Shanghai Rising-Star Program (19QA1408100).

Author contributions

Chunhui Bao drafted the manuscript. Jinrong Zhang revised the manuscript. Huangan Wu proposed revisions to the important intellectual content of the manuscript. All authors reviewed and approved the manuscript.

Ethical approval of studies and informed consent

Not applicable.

Acknowledgments

The authors would like to thank Prof. Xiaoming Jin at the Indiana University School of Medicine for his comments on the manuscript and language revisions.

Data availability

Not applicable.

References

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Song G, Fiocchi C, Achkar JP.Acupuncture in inflammatory bowel disease. Inflamm Bowel Dis. 2019;25(7):1129-1139.

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Bao CH, Wu LY, Wang D, et al.Acupuncture improves the symptoms, intestinal microbiota, and inflammation of patients with mild to moderate Crohn's disease: a randomized controlled trial. EClinicalMedicine. 2022;45:101300.

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Bao CH, Zhao JM, Liu HR, et al.Randomized controlled trial: moxibustion and acupuncture for the treatment of Crohn's disease. World J Gastroenterol. 2014;20(31):11000-11011.

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Bao CH, Wu LY, H R, et al. Acupuncture reduces clinical relapse in Crohn's disease: a randomized controlled trial J Gastroenterology 2023;164(6):S-1093.

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Han D, Liu HR, Wu HG, et al.Progression and reflection on the mechanism study of acupuncture and moxibustion in treatment of Crohn's disease. Acupunct Res. 2023;48(2):139-146.

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Bao CH, Wu LY, Wu HG, et al.Moxibustion inhibits apoptosis and tumor necrosis factor-alpha/tumor necrosis factor receptor 1 in the colonic epithelium of Crohn's disease model rats. Dig Dis Sci. 2012;57(9):2286-2295.

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Shi Y, Li T, Zhou J, et al.Herbs-partitioned moxibustion combined with acupuncture inhibits TGF-β1-Smad-Snail-induced intestinal epithelial mesenchymal transition in Crohn's disease model rats. Evid Based Complement Alternat Med. 2019;2019:8320250.

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Zhang J, Wang XJ, Wu LJ, et al.Herb-partitioned moxibustion alleviates colonic inflammation in Crohn's disease rats by inhibiting hyperactivation of the NLRP3 inflammasome via regulation of the P2X7R-Pannexin-1 signaling pathway. PLoS One. 2021;16(5):e0252334.

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Bao CH, Liu P, Liu HR, et al.Different brain responses to electro-acupuncture and moxibustion treatment in patients with Crohn's disease. Sci Rep. 2016;6:36636.

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Lu Y, Ding G, Zheng H, et al.Effect of herb-partitioned moxibustion on dopamine levels and dopamine receptor 1 expression in the colon and central nervous system in rats with Crohn's disease. J Tradit Chin Med. 2019;39(3):356-363.

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Wang J, Xia XH, Ye M, et al.Influence of different quantity of moxibustion on colon damage and serum IgG, IgA, IgM level in rats with Crohn's disease. J Tianjin Univ Trad Chinese Med. 2014;33(1):22-25.

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Cui X, Zhang W, Sun JH, et al.Correlation between referred pain distribution and acupoint sensitization in patients with intestinal diseases. Chinese Acupunct Moxibustion. 2019;39(11):1193-1198.

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