Metal-Organic Frameworks: A Potential Platform From Enzyme Immobilization to Mimetic Enzyme

Abstract

Metal-organic frameworks (MOFs) are a new class of organic-inorganic hybrid materials that have been widely studied in the past two decades for their potential in catalysis. (1) In this review, we comprehensively summarize the synthesis, application, and potential advancements of MOFs in enzyme immobilization and mimetic enzymes. (2) We also discuss the design principles behind various MOF-based biocatalysts, such as enzyme@MOF composites, and explore their utility in various reactions. (3) Additionally, we highlight the advantages of MOF materials as enzyme mimetics and provide a perspective on potential solutions to current challenges in MOF catalysis. (4) Ultimately, this review provides a general overview of the most recent advances in MOF-based catalyst platforms, including enzyme@MOF biocatalysts and MOF-based nanozymes, in various applications.

Keywords

catalysts / immobilized enzyme / metal-organic frameworks / mimetic enzyme

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