Developing Intermetallic Compound Nanomaterials for Electrocatalytic Oxidation of Organic Compounds to Value-Added Chemicals

Abstract

Electrocatalytic oxidation of organic compounds provides a green strategy to produce value-added chemicals from easily accessible molecules with low values at ambient conditions. The low overpotentials of these reactions also make them excellent alternatives to replace the conventional anodic oxygen evolution reaction in water splitting to reduce the electrical energy consumption of the electrolyser and simultaneously realize the co-production of fine chemicals and hydrogen. However, the electrocatalytic oxidation of organic compounds suffers from slow kinetics and complex reaction pathways, which lead to poor catalytic activity and selectivity, hindering its practical applications in green production of value-added chemicals. Recently, intermetallic compound (IMC) nanomaterials have shown great promise as catalysts for electrocatalytic oxidation of organic compounds. Their atomically ordered structures enable the precise control over the configurations of active sites, making it feasible to finely modulate the adsorption of reactants and intermediates on catalyst surface for achieving high electrocatalytic performance. This review provides a brief overview of the development of IMC nanomaterials as catalysts for electrocatalytic oxidation of organic compounds to produce value-added chemicals. The main strategies for preparing IMC nanomaterials are summarized, followed by an overview of their applications in electrocatalytic oxidation of furan compounds, glycerol, and plastic waste. Besides, the hybrid water splitting systems coupling electrocatalytic oxidation reactions with hydrogen evolution reaction utilizing IMC nanomaterials as catalysts are also highlighted. Finally, the existing challenges and future research opportunities in this research area are discussed.

Keywords

coupled electrolysers / electrocatalysis / electrocatalytic oxidation reactions / intermetallic compounds

References

[1] X. Wu, Y. Wang, and Z.-S. Wu, “Design Principle of Electrocatalysts for the Electrooxidation of Organics,” Chem 8 (2022): 2594–2629.

[2] C. Yang, L. Zhang, Y. Lu, Y. Zou, and S. Wang, “Designing Efficient Catalysts for Electrocatalytic Organic Synthesis: From Electronic Structure to Adsorption Behavior,” Matter 7 (2024): 456–474.

[3] P. De Luna, C. Hahn, D. Higgins, S. A. Jaffer, T. F. Jaramillo, and E. H. Sargent, “What Would It Take for Renewably Powered Electrosynthesis to Displace Petrochemical Processes?,” Science 364 (2019): eaav3506.

[4] C. Tang, Y. Zheng, M. Jaroniec, and S. Z. Qiao, “Electrocatalytic Refinery for Sustainable Production of Fuels and Chemicals,” Angewandte Chemie International Edition 60 (2021): 19572–19590.

[5] D. Li, “Frontiers in Catalytic Technologies for Carbon Neutrality: Advances and Prospects,” Chemical Research in Chinese Universities 41 (2025): 472–483.

[6] S. Furukawa, A. Suga, and T. Komatsu, “Mechanistic Study on Aerobic Oxidation of Amine over Intermetallic Pd₃Pb: Concerted Promotion Effects by Pb and Support Basicity,” ACS Catalysis 5 (2015): 1214–1222.

[7] P. Adamski, H. Zhang, S. Kaur, X. Chen, C. Liang, and M. Armbrüster, “Selective Hydrogenation of α,β-Unsaturated Aldehydes Over Intermetallic Compounds─a Critical Review,” Chemistry of Materials 36 (2024): 10383–10407.

[8] H. Liu, X. Chen, S. Liu, et al., “Catalysts Derived from Al–Ni Intermetallic Compounds for Efficient Selective Semihydrogenation of Phenylacetylene,” Industrial & Engineering Chemistry Research 63 (2024): 3608–3620.

[9] K. Li and Y. Sun, “Electrocatalytic Upgrading of Biomass-Derived Intermediate Compounds to Value-Added Products,” Chemistry—A European Journal 24 (2018): 18258–18270.

[10] M. Yang, Z. Yuan, R. Peng, S. Wang, and Y. Zou, “Recent Progress on Electrocatalytic Valorization of Biomass-Derived Organics,” Energy & Environmental Materials 5 (2022): 1117–1138.

[11] L. Guo, X. Zhang, L. Gan, et al., “Advances in Selective Electrochemical Oxidation of 5-Hydroxymethylfurfural to Produce High-Value Chemicals,” Advanced Science 10 (2023): 2205540.

[12] Y. Ren, W. Kong, Y. Li, et al., “Selective Electrooxidation of 5-hydroxymethylfurfural at Pilot Scale by Engineering a Solid Polymer Electrolyte Reactor,” Nature Catalysis 8 (2025): 771–783.

[13] J. Wu, X. Yang, and M. Gong, “Recent Advances in Glycerol Valorization via Electrooxidation: Catalyst, Mechanism and Device,” Chinese Journal of Catalysis 43 (2022): 2966–2986.

[14] S. Wang, Y. Lin, Y. Li, et al., “Nanoscale High-Entropy Surface Engineering Promotes Selective Glycerol Electro-Oxidation to Glycerate at High Current Density,” Nature Nanotechnology 20 (2025): 646–655.

[15] S. Yue, P. Wang, B. Yu, et al., “From Plastic Waste to Treasure: Selective Upcycling through Catalytic Technologies,” Advanced Energy Materials 13 (2023): 2302008.

[16] H. Zhou, Y. Ren, Z. Li, et al., “Electrocatalytic Upcycling of Polyethylene Terephthalate to Commodity Chemicals and H₂ Fuel,” Nature Communications 12 (2021): 4679.

[17] J. Chen, F. Zhang, M. Kuang, et al., “Unveiling Synergy of Strain and Ligand Effects in Metallic Aerogel for Electrocatalytic Polyethylene Terephthalate Upcycling,” Proceedings of the National Academy of Sciences of the United States of America 121 (2024): e2318853121.

[18] J. Li and H. Duan, “Recent Progress in Energy-Saving Hydrogen Production by Coupling with Value-Added Anodic Reactions,” Chem 10 (2024): 3008–3039.

[19] Y. Qin, Y. Wang, G. Jin, X. Tong, and N. Yang, “Construction and Progress of Small Molecule-Based Coupled Electrolyzers,” Advanced Energy Materials 14 (2024): 2402429.

[20] T. Li and D. A. Harrington, “An Overview of Glycerol Electrooxidation Mechanisms on Pt, Pd and Au,” ChemSusChem 14 (2021): 1472–1495.

[21] Y. Nakaya and S. Furukawa, “Catalysis of Alloys: Classification, Principles, and Design for a Variety of Materials and Reactions,” Chemical Reviews 123 (2022): 5859–5947.

[22] Y. Yan, J. S. Du, K. D. Gilroy, D. Yang, Y. Xia, and H. Zhang, “Intermetallic Nanocrystals: Syntheses and Catalytic Applications,” Advanced Materials 29 (2017): 1605997.

[23] Q. Mai, Y. Mai, Y. Zhong, et al., “Intermetallic Electrocatalysts for Small-Molecule Fuel Oxidation,” Advanced Energy Materials 15 (2025): 2500415.

[24] M. Song, Y. Wu, Z. Zhao, M. Zheng, C. Wang, and J. Lu, “Corrosion Engineering of Part-per-Million Single Atom Pt₁/Ni(OH)₂ Electrocatalyst for PET Upcycling at Ampere-Level Current Density,” Advanced Materials 36 (2024): 2403234.

[25] N.-Y. Huang, B. Chu, D. Chen, et al., “Rational Design of a Quasi-Metal–Organic Framework by Ligand Engineering for Efficient Biomass Upgrading,” Journal of the American Chemical Society 147 (2025): 8832–8840.

[26] C. Zhu, S. Fu, Q. Shi, D. Du, and Y. Lin, “Single-Atom Electrocatalysts,” Angewandte Chemie International Edition 56 (2017): 13944–13960.

[27] W. Wang, K. Yang, Q. Zhu, et al., “MOFs-Based Materials With Confined Space: Opportunities and Challenges for Energy and Catalytic Conversion,” Small 20 (2024): 2311449.

[28] M. Luo, Y. Sun, L. Wang, and S. Guo, “Tuning Multimetallic Ordered Intermetallic Nanocrystals for Efficient Energy Electrocatalysis,” Advanced Energy Materials 7 (2017): 1602073.

[29] J. Li and S. Sun, “Intermetallic Nanoparticles: Synthetic Control and Their Enhanced Electrocatalysis,” Accounts of Chemical Research 52 (2019): 2015–2025.

[30] M. Zhou, C. Li, and J. Fang, “Noble-Metal Based Random Alloy and Intermetallic Nanocrystals: Syntheses and Applications,” Chemical Reviews 121 (2020): 736–795.

[31] S. Han, C. He, Q. Yun, et al., “Pd-Based Intermetallic Nanocrystals: From Precise Synthesis to Electrocatalytic Applications in Fuel Cells,” Coordination Chemistry Reviews 445 (2021): 214085.

[32] F. Lin, M. Li, L. Zeng, M. Luo, and S. Guo, “Intermetallic Nanocrystals for Fuel-Cells-Based Electrocatalysis,” Chemical Reviews 123 (2023): 12507–12593.

[33] C.-L. Yang, L.-N. Wang, P. Yin, et al., “Sulfur-Anchoring Synthesis of Platinum Intermetallic Nanoparticle Catalysts for Fuel Cells,” Science 374 (2021): 459–464.

[34] H. Y. Kim, T. Kwon, Y. Ha, et al., “Intermetallic PtCu Nanoframes as Efficient Oxygen Reduction Electrocatalysts,” Nano Letters 20 (2020): 7413–7421.

[35] P. Wang, K. Chen, J. Chen, G. Wang, W. Pan, and Z. Wen, “Trifunctional Intermetallic PtZn-Based Electrocatalyst for Integrated Hybrid Acid/Alkali Electrochemical Cell Toward Glycerol Conversion and H₂ Generation,” Advanced Functional Materials 34 (2024): 2408267.

[36] G. Jiang, H. Zhu, X. Zhang, et al., “Core/Shell Face-Centered Tetragonal FePd/Pd Nanoparticles as an Efficient Non-Pt Catalyst for the Oxygen Reduction Reaction,” ACS Nano 9 (2015): 11014–11022.

[37] S. Bernal, J. Calvino, J. Gatica, C. Larese, C. López-Cartes, and J. Pérez-Omil, “Nanostructural Evolution of a Pt/CeO₂ Catalyst Reduced at Increasing Temperatures (473–1223 K): A HREM Study,” Journal of Catalysis 169 (1997): 510–515.

[38] C. Li, Y. Chen, S. Zhang, et al., “Ni–In Intermetallic Nanocrystals as Efficient Catalysts toward Unsaturated Aldehydes Hydrogenation,” Chemistry of Materials 25 (2013): 3888–3896.

[39] Z. Li, Z. Qi, S. Wang, et al., “In Situ Formed Pt₃Ti Nanoparticles on a Two-Dimensional Transition Metal Carbide (MXene) Used as Efficient Catalysts for Hydrogen Evolution Reactions,” Nano Letters 19 (2019): 5102–5108.

[40] Z. Li, L. Yu, C. Milligan, et al., “Two-Dimensional Transition Metal Carbides as Supports for Tuning the Chemistry of Catalytic Nanoparticles,” Nature Communications 9 (2018): 5258.

[41] S. Zhang, S. Guo, H. Zhu, D. Su, and S. Sun, “Structure-Induced Enhancement in Electrooxidation of Trimetallic FePtAu Nanoparticles,” Journal of the American Chemical Society 134 (2012): 5060–5063.

[42] H. Wang, Y. Li, X. Chen, et al., “Effect of Cu Doping on the Structure and Phase Transition of Directly Synthesized FePt Nanoparticles,” Journal of Magnetism and Magnetic Materials 422 (2017): 470–474.

[43] J. Liang, Y. Wan, H. Lv, et al., “Metal Bond Strength Regulation Enables Large-Scale Synthesis of Intermetallic Nanocrystals for Practical Fuel Cells,” Nature Materials 23 (2024): 1259–1267.

[44] L. Bu, N. Zhang, S. Guo, et al., “Biaxially Strained PtPb/Pt Core/Shell Nanoplate Boosts Oxygen Reduction Catalysis,” Science 354 (2016): 1410–1414.

[45] C. Roychowdhury, F. Matsumoto, V. B. Zeldovich, et al., “Synthesis, Characterization, and Electrocatalytic Activity of PtBi and PtPb Nanoparticles Prepared by Borohydride Reduction in Methanol,” Chemistry of Materials 18 (2006): 3365–3372.

[46] S. Maksimuk, S. Yang, Z. Peng, and H. Yang, “Synthesis and Characterization of Ordered Intermetallic PtPb Nanorods,” Journal of the American Chemical Society 129 (2007): 8684–8685.

[47] W. Lei, J. Xu, Y. Yu, W. Yang, Y. Hou, and D. Chen, “Halide Ion-Mediated Synthesis of L1₀-FePt Nanoparticles With Tunable Magnetic Properties,” Nano Letters 18 (2018): 7839–7844.

[48] A. L. Wang, L. Zhu, Q. Yun, et al., “Bromide Ions Triggered Synthesis of Noble Metal–Based Intermetallic Nanocrystals,” Small 16 (2020): 2003782.

[49] B. Huang, Y. Ge, A. Zhang, et al., “Seeded Synthesis of Hollow PdSn Intermetallic Nanomaterials for Highly Efficient Electrocatalytic Glycerol Oxidation,” Advanced Materials 35 (2023): 2302233.

[50] J. Yu, Y. Yin, and W. Huang, “Engineered Interfaces for Heterostructured Intermetallic Nanomaterials,” Nature Synthesis 2 (2023): 749–756.

[51] F. Feng, S. Han, Q. Lu, and Q. Yun, “Two-Dimensional Noble Metal-Based Intermetallics for Electrocatalysis,” Energy Materials and Devices 1 (2023): 9370008.

[52] L. Bu, S. Guo, X. Zhang, et al., “Surface Engineering of Hierarchical Platinum-Cobalt Nanowires for Efficient Electrocatalysis,” Nature Communications 7 (2016): 11850.

[53] Q. Yun, Q. Lu, C. Li, et al., “Synthesis of PdM (M = Zn, Cd, ZnCd) Nanosheets with an Unconventional Face-Centered Tetragonal Phase as Highly Efficient Electrocatalysts for Ethanol Oxidation,” ACS Nano 13 (2019): 14329–14336.

[54] J. Yan, W. Yu, Z. Wang, L. Wu, Y. Wang, and T. Xu, “Review on High-Performance Polymeric Bipolar Membrane Design and Novel Electrochemical Applications,” Aggregate 5 (2024): e527.

[55] J. Liu, G. Fu, Y. Liao, et al., “Electrochemical Conversion of Small Organic Molecules to Value-Added Chemicals and Hydrogen/Electricity Without CO₂ Emission: Electrocatalysts, Devices and Mechanisms,” eScience 5 (2025): 100267.

[56] S. Sun, Z. Liu, Z. J. Xu, and T. Wu, “Opportunities and Challenges in Biomass Electrocatalysis and Valorization,” Applied Catalysis B: Environment and Energy 358 (2024): 124404.

[57] C.-Y. Wang, Z.-Y. Yu, G. Li, et al., “Intermetallic PtBi Nanoplates with High Catalytic Activity Towards Electro-Oxidation of Formic Acid and Glycerol,” ChemElectroChem 7 (2020): 239–245.

[58] Y. Jing, Y. Guo, Q. Xia, X. Liu, and Y. Wang, “Catalytic Production of Value-Added Chemicals and Liquid Fuels from Lignocellulosic Biomass,” Chem 5 (2019): 2520–2546.

[59] Y. Ren, S. Fan, X. Yu, et al., “Advances in the Energy-Saving Electro-Oxidation of 5-Hydroxymethylfurfural to 2,5-Furandicarboxylic Acid,” Advanced Sustainable Systems 9 (2025): 2400959.

[60] Y. Yang and T. Mu, “Electrochemical Oxidation of Biomass Derived 5-hydroxymethylfurfural (HMF): Pathway, Mechanism, Catalysts and Coupling Reactions,” Green Chemistry 23 (2021): 4228–4254.

[61] Z. Zheng, K. Li, L. Lin, Z. Jiang, Y. Wang, and K. Yan, “Recent Advances on the Electrocatalytic Oxidation of Biomass-Derived Aldehydes,” Green Energy & Environment 10 (2025): 898–916.

[62] L. Shi, W. Cai, F. Zhang, et al., “Engineering Oxygen Intermediates Adsorption on Amorphous NiFe Alloys for Highly Active and Selective Electrochemical Biomass Conversion,” Angewandte Chemie International Edition 64 (2025): e202424345.

[63] X. Liu, J. Tang, Y. Chen, et al., “Refining Electrocatalyst Design for 5-Hydroxymethylfurfural Oxidation: Insights into Electrooxidation Mechanisms, Structure–Property Correlations, and Optimization Strategies,” ACS Catalysis 15 (2025): 7308–7339.

[64] J. Lei, H. Zhang, J. Yang, et al., “Structural Designs and Mechanism Insights into Electrocatalytic Oxidation of 5-hydroxymethylfurfural,” Journal of Energy Chemistry 100 (2025): 792–814.

[65] D. J. Chadderdon, L. Xin, J. Qi, et al., “Electrocatalytic Oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic Acid on Supported Au and Pd Bimetallic Nanoparticles,” Green Chemistry 16 (2014): 3778–3786.

[66] M. Park, M. Gu, and B.-S. Kim, “Tailorable Electrocatalytic 5-Hydroxymethylfurfural Oxidation and H₂ Production: Architecture–Performance Relationship in Bifunctional Multilayer Electrodes,” ACS Nano 14 (2020): 6812–6822.

[67] X. Y. Zhang, S.-S. Yu, J.-J. Chen, K. Gao, H.-Q. Yu, and Y. Yu, “Electrocatalytic Biomass Oxidation via Acid-Induced In Situ Surface Reconstruction of Multivalent State Coexistence in Metal Foams,” Advanced Materials 37 (2025): 2419050.

[68] Z. Liu, T. Xiao, X. Wu, et al., “Cu-induced Ni³⁺-O Active Sites in Prussian Blue Analogues Enable Nearly 100 % Selective Electrooxidation of 5-hydroxymethylfurfural to Produce Kilogram-scale 2,5-furandicarboxylic Acid,” Applied Catalysis B: Environment and Energy 378 (2025): 125601.

[69] C. Gong, H. Chen, J. Zeng, Q. Liu, C. Li, and J. He, “Typical Metal Catalysts for Electro-oxidation of 5-Hydroxymethylfurfural (HMF),” Inorganic Chemistry Communications 177 (2025): 114356.

[70] B. Chakraborty, R. Beltrán-Suito, J. N. Hausmann, S. Garai, M. Driess, and P. W. Menezes, “Enabling Iron-Based Highly Effective Electrochemical Water-Splitting and Selective Oxygenation of Organic Substrates through In Situ Surface Modification of Intermetallic Iron Stannide Precatalyst,” Advanced Energy Materials 10 (2020): 2001377.

[71] J. N. Hausmann, R. Beltrán-Suito, S. Mebs, et al., “Evolving Highly Active Oxidic Iron(III) Phase from Corrosion of Intermetallic Iron Silicide to Master Efficient Electrocatalytic Water Oxidation and Selective Oxygenation of 5-Hydroxymethylfurfural,” Advanced Materials 33 (2021): 2008823.

[72] T. Attarbachi, M. D. Kingsley, and V. Spallina, “New Trends on Crude Glycerol Purification: A Review,” Fuel 340 (2023): 127485.

[73] H. Ye, S. Favero, H. Tyrrell, et al., “Progress and Challenges in Electrochemical Glycerol Oxidation: The Importance of Benchmark Methods and Protocols,” ChemCatChem 17 (2025): e00152.

[74] D. Wu, S. Liu, Y. Nie, et al., “Electrocatalytic Upgrading of Glycerol into High-Value Products: Catalyst Design, Process Engineering, and Economic Assessment,” Chemical Engineering Journal 518 (2025): 164511.

[75] J. Li, Y. Pan, H. Yan, et al., “Recent Advances in Pt-Based Ordered Intermetallic Catalysts for Glycerol Oxidation,” Industrial & Engineering Chemistry Research 64 (2025): 5099–5113.

[76] Y. Li, X. Wei, R. Pan, et al., “PtAu Alloying-Modulated Hydroxyl and Substrate Adsorption for Glycerol Electrooxidation to C₃ Products,” Energy & Environmental Science 17 (2024): 4205–4215.

[77] J. Li, Y. Zhang, L. Zhang, et al., “Facilitating OH* Generation on Atomic Pd–Cu Dual Sites towards Efficient Glycerol Electrooxidation to Formate,” Angewandte Chemie International Edition 64 (2025): e202425006.

[78] H. Chen, R.-T. Gao, K. Su, Z. Li, L. Wu, and L. Wang, “Re and Ru Co-Doped Transition Metal Alloy as a Bifunctional Catalyst for Electrooxidation of Glycerol to Formate Coupled with H₂ Production,” Angewandte Chemie International Edition 64 (2025): e202501766.

[79] C. Li, T. Azam, S. Li, et al., “Electrooxidation of Glycerol to Formic Acid: From Catalyst Design Strategies to Key Coupled Systems,” ChemSusChem 18 (2025): e202500220.

[80] X. Hu, J. Lu, Y. Liu, L. Chen, X. Zhang, and H. Wang, “Sustainable Catalytic Oxidation of Glycerol: A Review,” Environmental Chemistry Letters 21 (2023): 2825–2861.

[81] K. M. Naik, K. Hashisake, T. Hamada, E. Higuchi, and H. Inoue, “Intermetallic PdZn Nanoparticles Loaded on Deficient TiO₂ Nanosheets as a Support: A Bifunctional Electrocatalyst for Oxygen Reduction in PEMFCs and the Glycerol Oxidation Reactions,” Journal of Materials Chemistry A 10 (2022): 13987–13997.

[82] X. Zhang, X. Sun, M. Li, et al., “Ordered Pt₃ Mn Intermetallic Setting the Maximum Threshold Activity of Disordered Variants for Glycerol Electrolysis,” ACS Nano 19 (2025): 7154–7167.

[83] N. Lyu, Y. Chen, A. Guan, et al., “Electrocatalytic Glycerol Upgrading into Glyceric Acid on Ni₃Sn Intermetallic Compound,” Small 20 (2024): 2401872.

[84] A. A. Ahmed, M. Alyami, A. AlArjani, et al., “Recent Progress on Recycling and Upcycling of PET Plastic Waste into High-Value-Added Materials for Versatile Applications,” Journal of Environmental Chemical Engineering 13 (2025): 116678.

[85] S. Han, J. Wang, Y. Li, C. Wang, Y. Wu, and B. Liu, “Strategies for Electrochemical Recycling of Plastic Polyethylene Terephthalate-Derived Ethylene Glycol Into High-Value Chemicals,” Advanced Energy Materials 15 (2025): 2502368.

[86] X. Yang, Q. Yuan, T. Sheng, and X. Wang, “Mesoporous Mo-Doped PtBi Intermetallic Metallene Superstructures to Enable the Complete Electrooxidation of Ethylene Glycol,” Chemical Science 15 (2024): 4349–4357.

[87] X. Yang, K. Yao, J. Y. Ye, et al., “Interface-Rich Three-Dimensional Au-Doped PtBi Intermetallics as Highly Effective Anode Catalysts for Application in Alkaline Ethylene Glycol Fuel Cells,” Advanced Functional Materials 31 (2021): 2103671.

[88] J. Chen, J. Li, and Z. Wei, “Recent Advances in the Preparation of Glycolic Acid by Selective Electrocatalytic Oxidation of Ethylene Glycol,” Chinese Journal of Catalysis 73 (2025): 79–98.

[89] Y. Lin, Y. Chen, H. Ren, et al., “Inspiration of Bimetallic Peroxide for Controllable Electrooxidizing Ethylene Glycol Through Modulating Surficial Intermediates,” Advanced Functional Materials 34 (2024): 2404594.

[90] C. He, Y. Yan, Y. Fu, et al., “Incorporating Ordered Indium Sites into Rhodium for Ultra-Low Potential Electrocatalytic Conversion of Ethylene Glycol to Glycolic Acid,” Advanced Materials 37 (2025): 2418959.

[91] F. Feng, S. Han, C. Ma, et al., “Thiol-Modulation-Induced Mesoporous Nanosheets with an Alloy/Intermetallic Heterophase for Efficient Electrochemical Ethylene Glycol-Assisted Water Splitting,” Advanced Functional Materials 35 (2025): 2506541.

[92] J. Hao, T. Wang, J. Cai, et al., “Suppression of Structural Heterogeneity in High-Entropy Intermetallics for Electrocatalytic Upgrading of Waste Plastics,” Angewandte Chemie International Edition 64 (2025): e202419369.

[93] W. Zhang, M. Liu, X. Gu, Y. Shi, Z. Deng, and N. Cai, “Water Electrolysis toward Elevated Temperature: Advances, Challenges and Frontiers,” Chemical Reviews 123 (2023): 7119–7192.

[94] P. Wang, J. Zheng, X. Xu, et al., “Unlocking Efficient Hydrogen Production: Nucleophilic Oxidation Reactions Coupled With Water Splitting,” Advanced Materials 36 (2024): 2404806.

[95] J. Cheng, Y. Xiang, X. Huang, and Z. Wei, “Reducing Energy Costs During Hydrogen Production from Water Electrolysis by Coupling Small Molecule Oxidation: From Molecular Catalysis to Industrial Exploration,” Precision Chemistry 2 (2024): 447–470.

[96] J. Li, Y. Ma, X. Mu, et al., “Recent Advances and Perspectives on Coupled Water Electrolysis for Energy-Saving Hydrogen Production,” Advanced Science 12 (2025): 2411964.

[97] W. Gao, C. Wang, W. Wen, et al., “Electrochemical Hydrogen Production Coupling with the Upgrading of Organic and Inorganic Chemicals,” Advanced Materials 37 (2025): 2503198.

[98] X. Li, J. Sun, H. Ma, et al., “Efficient Metallic Ni as a Bifunctional Electrocatalyst for Integrating Continuous PET Plastic Upcycling with Hydrogen Production,” Applied Catalysis B: Environment and Energy 371 (2025): 125211.

[99] L. Quan, H. Jiang, G. Mei, Y. Sun, and B. You, “Bifunctional Electrocatalysts for Overall and Hybrid Water Splitting,” Chemical Reviews 124 (2024): 3694–3812.

[100] Y. Xu, J. Xie, Y. Sheng, et al., “Strong p–d Orbital Hybridization in Atomically Ordered Intermetallic Pd₃Bi Metallene Enables Energy-Efficient Simultaneous Electrosynthesis of a Nylon-6 Precursor and Glycolic Acid,” ACS Catalysis 15 (2025): 6606–6617.

[101] Z. Zhang, J. Li, S. Yang, and T. E. C. Peng, “Advances in Paired Electrolysis for Furfural Conversion: From Design Principle, Mechanisms to Perspectives,” Green Chemistry 27 (2025): 6967–6988.

[102] Q. Yun, Y. Ge, Z. Shi, et al., “Recent Progress on Phase Engineering of Nanomaterials,” Chemical Reviews 123 (2023): 13489–13692.

[103] C. Ma, L. Zheng, G. Wang, et al., “Phase Engineering of Metal-Organic Frameworks,” Aggregate 3 (2022): e145.

[104] F. Feng, C. Ma, S. Han, et al., “Breaking Highly Ordered PtPbBi Intermetallic with Disordered Amorphous Phase for Boosting Electrocatalytic Hydrogen Evolution and Alcohol Oxidation,” Angewandte Chemie International Edition 63 (2024): e202405173.

[105] H. Zhang, C. Ma, Y. C. Wang, et al., “Transition Metal-Gallium Intermetallic Compounds with Tailored Active Site Configurations for Electrochemical Ammonia Synthesis,” Angewandte Chemie International Edition 63 (2024): e202409515.

[106] Y. Chen, J. Liu, Q. Yun, et al., “Phase Engineering of Nanomaterials: Metal Nanomaterials,” Chemical Research in Chinese Universities 41 (2025): 370–413.

[107] W. Chen, S. Luo, M. Sun, et al., “High-Entropy Intermetallic PtRhBiSnSb Nanoplates for Highly Efficient Alcohol Oxidation Electrocatalysis,” Advanced Materials 34 (2022): 2206276.

[108] S. N. Alam, P. Shrivastava, D. Panda, B. Gunale, K. Susmitha, and P. Pola, “Synthesis of Al₂Cu Intermetallic Compound by Mechanical Alloying,” Materials Today Communications 31 (2022): 103267.

[109] H. Wu, F. Xiao, J. Wang, M. Gu, and M. Shao, “Highly Active and Durable Core-Shell Electrocatalysts for Proton Exchange Membrane Fuel Cells,” Nano Research 17 (2024): 8772–8784.

[110] Y. Zhou, W. Xiao, D. Wang, et al., “Highly Printable, Strong, and Ductile Ordered Intermetallic Alloy,” Nature Communications 16 (2025): 1036.

[111] B. Zhang, L. Zhang, H. Yang, et al., “Gram-Scale Synthesis of Small-Sized PtM Intermetallics as High-Performance Catalysts for the Hydrogen Evolution Reaction,” Chemical Communications 60 (2024): 5290–5293.

[112] B. Dasgupta, D. Bagchi, T. Sontheimer, M. Driess, and P. W. Menezes, “Dynamics in Electrochemical Organic Oxidation Reactions from In Situ and Operando Techniques,” Nature Reviews Chemistry 9 (2025): 766–789.

[113] J. Sun, Y. Lv, H. Chang, H. Ou, Y. Li, and G. Yang, “Modeling of Three-Dimensional Flow Cell Reactor with Serpentine Channel for Nitrate Electroreduction to Ammonia,” Chemical Engineering Science 315 (2025): 121845.

[114] N. Weber, M. Möntmann, M. Wessling, and R. Keller, “A Continuous Flow Reactor for Tubular Gas Diffusion Electrodes,” Chemical Engineering Journal 486 (2024): 150031.

[115] Z. Peng, Y. Gu, and Y. Sun, “Stacked Multi-Membrane Electrochemical System Achieving Simultaneous Salt Recovery and Organics Degradation in High Salinity Wastewaters,” Chemical Engineering Journal 515 (2025): 163408.

[116] Y. Liu, X. Chang, and B. Xu, “An Atom-Efficient Electrosynthesis Strategy for Organic Halides,” Chinese Journal of Catalysis 78 (2025): 170–181.

[117] Y. Ji, C. Liu, T. Zheng, and C. Xia, “Plastic Waste Upcycling through Electrocatalysis,” Current Opinion in Electrochemistry 52 (2025): 101712.

[118] X. Wang, Y. Chen, F. Li, et al., “Site-Selective Protonation Enables Efficient Carbon Monoxide Electroreduction to Acetate,” Nature Communications 15 (2024): 616.

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