Advanced Biotechnology journal publishes Article, Review, Protocol, Letter, Methodology and Case Study.
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Authors wishing to include figures, tables, or text passages that have already been published elsewhere are required to obtain permission from the copyright owner(s) for both the print and online format and to include evidence that such permission has been granted when submitting their papers. Any material received without such evidence will be assumed to originate from the authors.
Please follow the hyperlink “Submit manuscript” on the right and upload all of your manuscript files following the instructions given on the screen.
Please ensure you provide all relevant editable source files. Failing to submit these source files might cause unnecessary delays in the review and production process.
Please make sure your title page contains the following information.
Title
The title should be concise and informative.
Author information
If address information is provided with the affiliation(s) it will also be published.
For authors that are (temporarily) unaffiliated we will only capture their city and country of residence, not their e-mail address unless specifically requested.
Large Language Models (LLMs), such as ChatGPT, do not currently satisfy our authorship criteria. Notably an attribution of authorship carries with it accountability for the work, which cannot be effectively applied to LLMs. Use of an LLM should be properly documented in the Methods section (and if a Methods section is not available, in a suitable alternative part) of the manuscript. The use of an LLM (or other AI-tool) for "AI assisted copy editing" purposes does not need to be declared. In this context, we define the term "AI assisted copy editing" as AI-assisted improvements to human-generated texts for readability and style, and to ensure that the texts are free of errors in grammar, spelling, punctuation and tone. These AI-assisted improvements may include wording and formatting changes to the texts, but do not include generative editorial work and autonomous content creation. In all cases, there must be human accountability for the final version of the text and agreement from the authors that the edits reflect their original work.
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The following statements should be included under the heading "Statements and Declarations" for inclusion in the published paper. Please note that submissions that do not include relevant declarations will be returned as incomplete.
Please see the relevant sections in the submission guidelines for further information as well as various examples of wording. Please revise/customize the sample statements according to your own needs.
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Footnotes to the text are numbered consecutively; those to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data). Footnotes to the title or the authors of the article are not given reference symbols.
Always use footnotes instead of endnotes.
Acknowledgments of people, grants, funds, etc. should be placed in a separate section on the title page. The names of funding organizations should be written in full.
Cite references in the text by name and year in parentheses. Some examples:
1. Negotiation research spans many disciplines (Thompson 1990).
2. This result was later contradicted by Becker and Seligman (1996).
3. This effect has been widely studied (Abbott 1991; Barakat et al. 1995; Kelso and Smith 1998; Medvec et al. 1999).
The list of references should only include works that are cited in the text and that have been published or accepted for publication. Personal communications and unpublished works should only be mentioned in the text.Do not use footnotes or endnotes as a substitute for a reference list.
Reference list entries should be alphabetized by the last names of the first author of each work.
Smith JJ. The world of science. Am J Sci. 1999; 36:234–5.
Slifka MK, Whitton JL. Clinical implications of dysregulated cytokine production. J Mol Med. 2000;https://doi.org/10.1007/s001090000086
Blenkinsopp A, Paxton P. Symptoms in the pharmacy: a guide to the management of common illness. 3rded. Oxford: Blackwell Science; 1998.
Wyllie AH, Kerr JFR, Currie AR. Cell death: the significance of apoptosis. In: Bourne GH, Danielli JF, Jeon KW, editors. International review of cytology. London: Academic; 1980. pp. 251–306.
Doe J. Title of subordinate document. In: The dictionary of substances and their effects. Royal Society of Chemistry. 1999. http://www.rsc.org/dose/title of subordinate document. Accessed 15 Jan 1999.
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This journal follows Springer Nature research data policy. Sharing of all relevant research data is strongly encouraged and authors must add a Data Availability Statement to original research articles.
Research data includes a wide range of types, including spreadsheets, images, textual extracts, archival documents, video or audio, interview notes or any specialist formats generated during research.
All original research must include a data availability statement. This statement should explain how to access data supporting the results and analysis in the article, including links/citations to publicly archived datasets analysed or generated during the study. Please see our full policy here.
If it is not possible to share research data publicly, for instance when individual privacy could be compromised, this statement should describe how data can be accessed and any conditions for reuse. Participant consent should be obtained and documented prior to data collection. See our guidance on sensitive data for more information.
When creating a data availability statement, authors are encouraged to consider the minimal dataset that would be necessary to interpret, replicate and build upon the findings reported in the article.
Further guidance on writing a data availability statement, including examples, is available at:
Authors are strongly encouraged to deposit their supporting data in a publicly available repository. Sharing your data in a repository promotes the integrity, discovery and reuse of your research, making it easier for the research community to build on and credit your work.
See our data repository guidance for information on finding a suitable repository.
We recommend the use of discipline-specific repositories where available. For a number of data types, submission to specific public repositories is mandatory.
See our list of mandated data types.
The journal encourages making research data available under open licences that permit reuse. The journal does not enforce use of particular licences in third party repositories. You should ensure you have necessary rights to share any data that you deposit in a repository.
The journal recommends that authors cite any publicly available data on which the conclusions of the paper rely. This includes data the authors are sharing alongside their publication and any secondary data the authors have reused. Data citations should include a persistent identifier (such as a DOI), should be included in the reference list using the minimum information recommended by DataCite (Dataset Creator, Dataset Title, Publisher [repository], Publication Year, Identifier [e.g. DOI, Handle, Accession or ARK]) and follow journal style.
See our further guidance on citing datasets.
If the journal that you are submitting to uses double-anonymous peer review and you are providing reviewers with access to your data (for example via a repository link, supplementary information or data on request), it is strongly suggested that the authorship in the data is also anonymised. There are data repositories that can assist with this and/or will create a link to mask the authorship of your data.
Authors who need help understanding our data sharing policy, finding a suitable data repository, or organising and sharing research data can consult our Research Data Helpdesk for guidance.
See our FAQ page for more information on Springer Nature's research data policy.
This journal is committed to upholding the integrity of the scientific record. As a member of the Committee on Publication Ethics (COPE) the journal will follow the COPE guidelines on how to deal with potential acts of misconduct.
Authors should refrain from misrepresenting research results which could damage the trust in the journal, the professionalism of scientific authorship, and ultimately the entire scientific endeavour. Maintaining integrity of the research and its presentation is helped by following the rules of good scientific practice, which include*:
Important note: the journal may use software to screen for plagiarism.
*All of the above are guidelines and authors need to make sure to respect third parties rights such as copyright and/or moral rights.
Upon request authors should be prepared to send relevant documentation or data in order to verify the validity of the results presented. This could be in the form of raw data, samples, records, etc. Sensitive information in the form of confidential or proprietary data is excluded.
If there is suspicion of misbehavior or alleged fraud the Journal and/or Publisher will carry out an investigation following COPE guidelines. If, after investigation, there are valid concerns, the author(s) concerned will be contacted under their given e-mail address and given an opportunity to address the issue. Depending on the situation, this may result in the Journal’s and/or Publisher’s implementation of the following measures, including, but not limited to:
- an erratum/correction may be placed with the article
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- or in severe cases retraction of the article may occur.
The reason will be given in the published erratum/correction, expression of concern or retraction note. Please note that retraction means that the article is maintained on the platform, watermarked “retracted” and the explanation for the retraction is provided in a note linked to the watermarked article.
Authors have an obligation to correct mistakes once they discover a significant error or inaccuracy in their published article. The author(s) is/are requested to contact the journal and explain in what sense the error is impacting the article. A decision on how to correct the literature will depend on the nature of the error. This may be a correction or retraction. The retraction note should provide transparency which parts of the article are impacted by the error.
Authors are welcome to suggest suitable reviewers and/or request the exclusion of certain individuals when they submit their manuscripts. When suggesting reviewers, authors should make sure they are totally independent and not connected to the work in any way. It is strongly recommended to suggest a mix of reviewers from different countries and different institutions. When suggesting reviewers, the Corresponding Author must provide an institutional email address for each suggested reviewer, or, if this is not possible to include other means of verifying the identity such as a link to a personal homepage, a link to the publication record or a researcher or author ID in the submission letter. Please note that the Journal may not use the suggestions, but suggestions are appreciated and may help facilitate the peer review process.
Authors are requested to disclose interests that are directly or indirectly related to the work submitted for publication. Interests within the last 3 years of beginning the work (conducting the research and preparing the work for submission) should be reported. Interests outside the 3-year time frame must be disclosed if they could reasonably be perceived as influencing the submitted work. Disclosure of interests provides a complete and transparent process and helps readers form their own judgments of potential bias. This is not meant to imply that a financial relationship with an organization that sponsored the research or compensation received for consultancy work is inappropriate.
Editorial Board Members and Editors are required to declare any competing interests and may be excluded from the peer review process if a competing interest exists. In addition, they should exclude themselves from handling manuscripts in cases where there is a competing interest. This may include – but is not limited to – having previously published with one or more of the authors, and sharing the same institution as one or more of the authors. Where an Editor or Editorial Board Member is on the author list we recommend they declare this in the competing interests section on the submitted manuscript. If they are an author or have any other competing interest regarding a specific manuscript, another Editor or member of the Editorial Board will be assigned to assume responsibility for overseeing peer review. These submissions are subject to the exact same review process as any other manuscript. Editorial Board Members are welcome to submit papers to the journal. These submissions are not given any priority over other manuscripts, and Editorial Board Member status has no bearing on editorial consideration.
Interests that should be considered and disclosed but are not limited to the following:
Funding: Research grants from funding agencies (please give the research funder and the grant number) and/or research support (including salaries, equipment, supplies, reimbursement for attending symposia, and other expenses) by organizations that may gain or lose financially through publication of this manuscript.
Employment: Recent (while engaged in the research project), present or anticipated employment by any organization that may gain or lose financially through publication of this manuscript. This includes multiple affiliations (if applicable).
Financial interests: Stocks or shares in companies (including holdings of spouse and/or children) that may gain or lose financially through publication of this manuscript; consultation fees or other forms of remuneration from organizations that may gain or lose financially; patents or patent applications whose value may be affected by publication of this manuscript.
It is difficult to specify a threshold at which a financial interest becomes significant, any such figure is necessarily arbitrary, so one possible practical guideline is the following: "Any undeclared financial interest that could embarrass the author were it to become publicly known after the work was published."
Non-financial interests: In addition, authors are requested to disclose interests that go beyond financial interests that could impart bias on the work submitted for publication such as professional interests, personal relationships or personal beliefs (amongst others). Examples include, but are not limited to: position on editorial board, advisory board or board of directors or other type of management relationships; writing and/or consulting for educational purposes; expert witness; mentoring relations; and so forth.
Primary research articles require a disclosure statement. Review articles present an expert synthesis of evidence and may be treated as an authoritative work on a subject. Review articles therefore require a disclosure statement. Other article types such as editorials, book reviews, comments (amongst others) may, dependent on their content, require a disclosure statement. If you are unclear whether your article type requires a disclosure statement, please contact the Editor-in-Chief.
Please note that, in addition to the above requirements, funding information (given that funding is a potential competing interest (as mentioned above)) needs to be disclosed upon submission of the manuscript in the peer review system. This information will automatically be added to the Record of CrossMark, however it is not added to the manuscript itself. Under ‘summary of requirements’ (see below) funding information should be included in the ‘Declarations’ section.
The above should be summarized in a statement and placed in a ‘Declarations’ section before the reference list under a heading of ‘Funding’ and/or ‘Competing interests’. Other declarations include Ethics approval, Consent, Data, Material and/or Code availability and Authors’ contribution statements.
Please see the various examples of wording below and revise/customize the sample statements according to your own needs.
When all authors have the same (or no) conflicts and/or funding it is sufficient to use one blanket statement.
Examples of statements to be used when funding has been received:
Examples of statements to be used when there is no funding:
Examples of statements to be used when there are interests to declare:
Non-financial interests: Author C is an unpaid member of committee Z.
Non-financial interests: Author A is on the board of directors of Y and receives no compensation as member of the board of directors.
Non-financial interests: none.
Non-financial interests: Author D has served on advisory boards for Company M, Company N and Company O.
Examples of statements to be used when authors have nothing to declare:
Authors are responsible for correctness of the statements provided in the manuscript. See also Authorship Principles. The Editor-in-Chief reserves the right to reject submissions that do not meet the guidelines described in this section.
The welfare of animals (vertebrate and higher invertebrate) used for research, education and testing must be respected. Authors should supply detailed information on the ethical treatment of their animals in their submission. For that purpose they may use the ARRIVE checklist which is designed to be used when submitting manuscripts describing animal research.
For studies involving client-owned animals, authors must also document informed consent from the client or owner and adherence to a high standard (best practice) of veterinary care.
Authors are recommended to comply with:
• The International Union for Conservation of Nature (IUCN) Policy Statement on Research Involving Species at Risk of Extinction and consult the IUCN red list index of threatened species.
• Convention on the Trade in Endangered Species of Wild Fauna and Flora
When reporting results authors should indicate:
• … that the studies have been approved by a research ethics committee at the institution or practice at which the studies were conducted. Please provide the name of ethics committee and relevant permit number;
• … whether the legal requirements or guidelines in the country and/or state or province for the care and use of animals have been followed.
Researchers from countries without any legal requirements or guidelines voluntarily should refer to the following sites for guidance:
– The Basel Declaration describes fundamental principles of using animals in biomedical research
– The International Council for Laboratory Animal Science (ICLAS) provides ethical guidelines for researchers as well as editors and reviewers
– The Association for the study of Animal Behaviour describes ethical guidelines for the treatment of animals in research and teaching
– The International Association of Veterinary Editors’ Consensus Author Guidelines on Animal Ethics provide guidelines for authors on animal ethics and welfare
Researchers may wish to consult the most recent (ethical) guidelines available from relevant taxon-oriented professional societies.
If a study was granted exemption or did not require ethics approval, this should also be detailed in the manuscript.
The above should be summarized in a statement and placed in a ‘Declarations’ section before the reference list under a heading of ‘Ethics approval’.
Please see the various examples of wording below and revise/customize the sample statements according to your own needs.
Examples of statements to be used when ethics approval has been obtained:
• All procedures involving animals were in compliance with the European Community Council Directive of 24 November 1986, and ethical approval was granted by the Kocaeli University Ethics Committee (No. 29 12 2014, Kocaeli, Turkey).
• All procedures performed in the study were in accordance with the ARVO Statement for Use of Animals in Ophthalmic Vision and Research. The ethical principles established by the National Institutes of Health Guide for the Care and Use of Laboratory Animals (NIH Publications No. 8523, revised 2011) were followed. The research protocol was approved by the Ethics Committee on Animal Use (Protocol No. 06174/14) of FCAV/Unesp, Jaboticabal.
• This study involved a questionnaire-based survey of farmers as well as blood sampling from their animals. The study protocol was assessed and approved by Haramaya University, research and extension office. Participants provided their verbal informed consent for animal blood sampling as well as for the related survey questions. Collection of blood samples was carried out by veterinarians adhering to the regulations and guidelines on animal husbandry and welfare.
• All brown bear captures and handling were approved by the Ethical Committee on Animal Experiments, Uppsala, Sweden (Application C18/15) and the Swedish Environmental Protection Agency in compliance with Swedish laws and regulations.
• The ethics governing the use and conduct of experiments on animals were strictly observed, and the experimental protocol was approved by the University of Maiduguri Senate committee on Medical Research ethics. Proper permit and consent were obtained from the Maiduguri abattoir management, before the faecal samples of the cattle and camels slaughtered in this abattoir were used for this experiment.
Examples of statements to be used when no ethical approval is required/exemption granted:
• No approval of research ethics committees was required to accomplish the goals of this study because experimental work was conducted with an unregulated invertebrate species.
• As the trappings of small mammals were conducted as part of regular pest control measures in accordance with the NATO Standardized Agreement 2048 "Deployment Pest and Vector Surveillance and Control ", no approval by an ethics committee was required.
• All experiments have been conducted as per the guidelines of the Institutional Animal Ethics Committee, Department of Zoology, Utkal University, Bhubaneswar, Odisha, India. However, the insect species used in this study is reared for commercial production of raw silk materials, as a part of agro-based industry. Therefore, use of this animal in research does not require ethical clearance. We have obtained permission from the office of Research officer sericulture, Baripada, Orissa, India for the provision of infrastructure and support for rearing of silkworm both in indoor and outdoor conditions related to our study to promote sericulture practices.
Authors are responsible for correctness of the statements provided in the manuscript. See also Authorship Principles. The Editor-in-Chief reserves the right to reject submissions that do not meet the guidelines described in this section.
These guidelines describe authorship principles and good authorship practices to which prospective authors should adhere to.
The Journal and Publisher assume all authors agreed with the content and that all gave explicit consent to submit and that they obtained consent from the responsible authorities at the institute/organization where the work has been carried out, before the work is submitted.
The Publisher does not prescribe the kinds of contributions that warrant authorship. It is recommended that authors adhere to the guidelines for authorship that are applicable in their specific research field. In absence of specific guidelines it is recommended to adhere to the following guidelines*:
All authors whose names appear on the submission
1) made substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data; or the creation of new software used in the work;
2) drafted the work or revised it critically for important intellectual content;
3) approved the version to be published; and
4) agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
* Based on/adapted from:
ICMJE, Defining the Role of Authors and Contributors,
All authors are requested to include information regarding sources of funding, financial or non-financial interests, study-specific approval by the appropriate ethics committee for research involving humans and/or animals, informed consent if the research involved human participants, and a statement on welfare of animals if the research involved animals (as appropriate).
The decision whether such information should be included is not only dependent on the scope of the journal, but also the scope of the article. Work submitted for publication may have implications for public health or general welfare and in those cases it is the responsibility of all authors to include the appropriate disclosures and declarations.
All authors are requested to make sure that all data and materials as well as software application or custom code support their published claims and comply with field standards. Please note that journals may have individual policies on (sharing) research data in concordance with disciplinary norms and expectations.
One author is assigned as Corresponding Author and acts on behalf of all co-authors and ensures that questions related to the accuracy or integrity of any part of the work are appropriately addressed.
The Corresponding Author is responsible for the following requirements:
* The requirement of managing all communication between the journal and all co-authors during submission and proofing may be delegated to a Contact or Submitting Author. In this case please make sure the Corresponding Author is clearly indicated in the manuscript.
In absence of specific instructions and in research fields where it is possible to describe discrete efforts, the Publisher recommends authors to include contribution statements in the work that specifies the contribution of every author in order to promote transparency. These contributions should be listed at the separate title page.
Examples of such statement(s) are shown below:
• Free text:
All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by [full name], [full name] and [full name]. The first draft of the manuscript was written by [full name] and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
• Conceptualization: [full name], …; Methodology: [full name], …; Formal analysis and investigation: [full name], …; Writing - original draft preparation: [full name, …]; Writing - review and editing: [full name], …; Funding acquisition: [full name], …; Resources: [full name], …; Supervision: [full name],….
For review articles where discrete statements are less applicable a statement should be included who had the idea for the article, who performed the literature search and data analysis, and who drafted and/or critically revised the work.
For articles that are based primarily on the student’s dissertation or thesis, it is recommended that the student is usually listed as principal author:
The primary affiliation for each author should be the institution where the majority of their work was done. If an author has subsequently moved, the current address may additionally be stated. Addresses will not be updated or changed after publication of the article.
Authors are strongly advised to ensure the correct author group, the Corresponding Author, and the order of authors at submission. Changes of authorship by adding or deleting authors, and/or changes in Corresponding Author, and/or changes in the sequence of authors are not accepted after acceptance of a manuscript.
Please make sure that the names of all authors are present and correctly spelled, and that addresses and affiliations are current.
Adding and/or deleting authors at revision stage are generally not permitted, but in some cases it may be warranted. Reasons for these changes in authorship should be explained. Approval of the change during revision is at the discretion of the Editor-in-Chief. Please note that journals may have individual policies on adding and/or deleting authors during revision stage.
Authors are recommended to use their ORCID ID when submitting an article for consideration or acquire an ORCID ID via the submission process.
For cases in which a co-author dies or is incapacitated during the writing, submission, or peer-review process, and the co-authors feel it is appropriate to include the author, co-authors should obtain approval from a (legal) representative which could be a direct relative.
In the case of an authorship dispute during peer review or after acceptance and publication, the Journal will not be in a position to investigate or adjudicate. Authors will be asked to resolve the dispute themselves. If they are unable the Journal reserves the right to withdraw a manuscript from the editorial process or in case of a published paper raise the issue with the authors’ institution(s) and abide by its guidelines.
Authors should treat all communication with the Journal as confidential which includes correspondence with direct representatives from the Journal such as Editors-in-Chief and/or Handling Editors and reviewers’ reports unless explicit consent has been received to share information.
Manuscripts that report experiments involving the use of human embryos and gametes, human embryonic stem cells and related materials, and clinical applications of stem cells must include confirmation that all experiments were performed in accordance with relevant guidelines and regulations (See also Research involving human participants, their data or biological material.
The manuscript should include an ethics statement identifying the institutional and/or national research ethics committee (including the name of the ethics committee) approving the experiments and describing any relevant details. Authors should confirm that informed consent (See also Informed Consent) was obtained from all recipients and/or donors of cells or tissues, where necessary, and describe the conditions of donation of materials for research, such as human embryos or gametes. Copies of approval and redacted consent documents may be requested by the Journal.
We encourage authors to follow the principles laid out in the ISSCR Guidelines for Stem Cell Research and Clinical Translation.
In deciding whether to publish papers describing modifications of the human germline, the Journal is guided by safety considerations, compliance with applicable regulations, as well as the status of the societal debate on the implications of such modifications for future generations. In case of concerns regarding a particular type of study the Journal may seek the advice from the Springer Nature Research Integrity Group.
The decision to publish a paper is the responsibility of the Editor-in-Chief of the Journal.
This journal values stewardship, transparency, and adhering to governance with regards to collecting and utilizing specimens and conducting experiments and/or field studies. Therefore the journal sets out the following guidelines:
Field studies involving genetically engineered plants must be conducted in accordance with national or local legislation and, if applicable, the manuscript needs to include a statement specifying the appropriate permissions and/or licences.
Authors utilizing genetic plant resources received via local suppliers/collectors, such as species collected from protected areas or endangered species with medical importance, must conduct their experiments following the Nagoya Protocol (as part of the Convention on Biological Diversity).
Authors whose research is focusing on quarantine organisms (i.e. harmful or pest organisms, including plant pathogens) should adhere to national legislation and notify the relevant National Plant Protection Organization of new findings before publication. More information can be found via the International Plant Protection Convention.
In principle, it is recommended that authors comply with:
Voucher specimens ensure that the identity of organisms studied in the field or in laboratory experiments can be verified, and ensure that new species concepts can be applied to past research. Voucher specimens documenting all investigated accessions (for population samples at least one specimen per population) are to be deposited in a public herbarium, for example: Index Herbariorum, or other public collection providing access to deposited material. Information on the voucher specimen and who identified it must be included in the manuscript such as Genus name, species name, author, and year of publication.
Manuscripts containing new taxon names or other nomenclatural acts must follow the guidelines set by the International Code of Nomenclature for algae, fungi, and plants.
Authors describing new fungal taxa should register the names with a recognized repository, such as Mycobank, and request a unique digital identifier which should be included in the published article.
This journal follows a single-blind reviewing procedure.
This journal also publishes special/guest-edited issues. The peer review process for these articles is the same as the peer review process of the journal in general.
Additionally, if a guest editor authors an article in their issue/collection, they will not handle the peer review process.
Peer-review is the system used to assess the quality of a manuscript before it is published. Independent researchers in the relevant research area assess submitted manuscripts for originality, validity and significance to help editors determine whether the manuscript should be published in their journal. The journal operates a single-blind peer-review system, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript. Submitted manuscripts will generally be reviewed by two or more experts who will be asked to evaluate whether the manuscript is scientifically sound and coherent, whether it duplicates already published work, and whether or not the manuscript is sufficiently clear for publication. The Editors will reach a decision based on these reports and, where necessary, they will consult with members of the Editorial Board.
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